Week 3 (3)

Question 1

What syndrome involves excess cortisol?

Answer 1

Cushings syndrome also excess mineralcorticoid and androgen

Question 2

What is characterised by thin skin, proximal myipathy, frontal balding in women, conjunctival oedema and osteoporosis?

Answer 2

Cushing ssyndrome (lemon on match sticks_

Question 3

How do you test for cushings?

Answer 3

Exogenous oral high dose dexamethasone - low serum cortisol (overnight 1mg dexamethasone suppression test)

Question 4

If ACTH is less than 300 what diagnosis is the cushings syndrome?

Answer 4

Pituitary - if over 300 uts ectopic

Question 5

Name three drugs used to treat cushings syndrome?

Answer 5

Metyrapone
Ketoconazole
Pasieeotide

Question 6

Does TB cause hypopituitarism?

Answer 6

Yes

Question 7

Name a cause of posterior hypopituitarism?

Answer 7

Diabetes Insipidus

Question 8

Give three risks of testosterone replacement?

Answer 8

Prostate enlargement
Polycuthaemia
Hepatitis

Question 9

How do you diagnose cranial diabetes insipidus?

Answer 9

Water deprivation test