Week 202 - Stroke Flashcards
What will telencephalon form?
Cerebrum
What will diencephalon form?
Thalamus, Hypothalamus
What will mesencephalon form?
Midbrain
What will metencephalon form?
cerebellum and pons
What artery is formed when the vertebral arteries form?
Basilar artery
What nerves pass through the cavernous sinus?
Abducent nerve (VI)
What nerves pass lateral to cavernous sinus?
Oculomotor nerve (III) Trochlear nerve (IV) Opthalmic nerve (V1) Maxillary nerve (V2)
What is the basic set of investigations after stroke?
FBC BP, ECG CXR CT +/- MR Lipids Glucose
What is lacunar infarct?
Small Infarct (<1cm diameter) Blockage of perforating vessels
Where is the most common place for a haemorrhage stroke to occur?
basal ganglia, cerebellum, pons
Increasingly important cause is cerebral amyloid antipathy (deposition of amyloid peptide)
Why are watershed zones particularly vulnerable to stroke?
Regions between arterial territories
What is the blood supply to the cerebellum?
Superior cerebellar artery (SCA) -from basilar
Anterior inferior cerebellar artery (AICA) -from basilar
Posterior inferior cerebellar artery (PICA) - from vertebral artery
What are the FOUR types of brain haemorrhage?
Primary brain haemorrhage
Extradural haemorrhage
Subdural haemorrhage
Subarachnoid haemorrhage
A lesion in which part of the brain may cause hemispatial neglect and sensory inattention?
Pariental Lobe
A damage to which area would give speech of robotic type?
Wernicke’s area
What is the definition of a STROKE?
Neurological deficit related to an atraumatic vascular event
What assessment is carried out for TIAs?
ABCD2
High risk pts (6-7) have a 8% two day reccurent stroke risk
What areas does the Anterior Cerebral Artery supply?
Medial and Superior aspects of frontal and parietal lobes
What areas does the Middle Cerebral Artery supply?
Lateral aspects of frontal, parietal & temporal lobes
What areas does the Posterior Cerebral Artery supply?
Occipital lobe
Inferior aspect of temporal lobe
What blood vessels “boost” the spinal arteries?
Radiculospinal branches (from vertebral and intercostal arteries)
What is the basic set of investigations in Stroke?
FBC BP ECG CXR CT Lipids, Glucose
What are the conditions for rTPA use in Stroke?
Thrombotic type
<3 hrs
no factors to ↑ICH
What medications are available for post-stroke prophylaxis?
Antiplatelet drugs: ASA+dipyridamole+clopidogrel
Anticoagulants: Warfarin (C/E stroke + CVST)
What are the most susceptible neurons in the brain to ischaemia?
Pyramidal cells of hippocampus & cortex
Purkinje cells of cerebellum
What are the conditions of brain perfusion?
Arterial BP > ICP
What is haemosiderosis?
Iron-overload
a complication of aneurysmal rupture
