Week 2 Sleep Flashcards
Purpose of sleep
Neurons used in the day shut down and repair themselves; cells reduce in size and allow for cleaning
Glymphatic systems
the brain’s unique waste disposal system; cerebral spinal fluid is pumped through the tissue and flushed into the circulatory system (then goes to the blood circulation system and to the liver).
Microsleeps
(Generally occurs when there is a cumulative sleep debt, during pre-dawn and/or mid-afternoon) some part of the brain effectively falls asleep while the rest is awake
Sleep Deprivation
Hippocampus loss, gray matter loss, and decreased activity in the frontal and temporal lobe; attention, vigilance, higher order decision making and mood difficulties
Sleep Cycles
Usually lasts 90 minutes, 4 distinct stages (wakefulness-REM)
Stage I
Less alpha waves and predominantly theta waves (like relaxation or meditation), serotonin and norepinephrine are released
calm and focused
Stage II
Light sleep; delta and theta waves- mostly theta, 50% of sleep
REM sleep
“sawtooth waves”, similar to being awake; serotonin and norepinephrine switch off, acetylcholine is released (twice as much as when awake) and dopamine- helps with learning and memory; entire nervous system increases activity, blood flow to brain increases
circadian rhythm
Body temp is a common marker, controlled by SCN located in hypothalamus
Caffeine
Binds up adenosine triphosphate (ATP), caffeine interferes with sleep for up to 10 hours,
Insomnia
difficulty initiating or maintaining sleep; treated with: ambien (activates GABA), benzodiazepine (GABA, risk of tolerance),