WEEK 2 Scheme Flashcards

1
Q

what is a leukopenia

A

a reduced white cell count

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2
Q

what is the normal WBC count

A

4-10 wc/ml (most are neutrophils)

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3
Q

what is it called when the wbc count is higher than 10

A

leukocytosis

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4
Q

what is it called when the wbc count is less than 10

A

leukopenia

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5
Q

what are the 2 main categories of leukopenia

A
neutropenia = decreased # neutrophils
Lymphopenia = decreased # of lymphocytes
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6
Q

when circulating neutrophils are less than 1500 aka less than 1.5 neutrophils / mL what does that mean

A

neutropenia

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7
Q

What are the common causes of neutropenia?

A

bacterial or fungal infections

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8
Q

What are common caues of lymphopenia

A

viral infections

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9
Q

what does lymphopenia mean

A

circulating lymphocytes are less than 1500

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10
Q

what does leukocytosis mean

A

circulating neutrophils are higher than 7000. The increased number of neutrophils is due to infection of inflammation

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11
Q

what does leukemoid reaction mean

A

the degree of wbc is so high that it starts to look like a leukemia, but it is not an actual leukemia

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12
Q

clonal elevations in wbc’s are called

A

leukemias

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13
Q

acute leukemias involve what kind of cells

A

blasts (immature cells) they affect children and the elderly and have short and drastic life course

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14
Q

what kind of cells are involved in chronic forms of leukemia

A

proliferation of mature cells, affect people in mid life and have a longer less devastating course

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15
Q

what can increased basophils on blood smear indicate

A

chronic myeloid leukemia

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16
Q

the risk of infection increases when the absolute neutrophil count is less than…

A

1000

17
Q

what is benign essential neutropenia

A

affects 40% of people of African origin . mild neutropenia without any symptoms

18
Q

a person has a leukocytosis with mostly neutrophils what is likely they cause of the infection

A

bacterial infection or corticosteroid therapy this is known as a left shift

19
Q

a person has a leukocytosis with mostly lymphocytes what is likely they cause of the infection

A

viral

20
Q

a person has a leukocytosis with mostly eosinophils what is likely the cause of the infection

A

fungal infections

21
Q

why is neutrophilia accompanied by fever

A

due to the release of leukocyte pyrogens

22
Q

what is a characteristic feature of reactive neutrophilia

A

shift to the left

23
Q

anytime basophilia is present, what leukemia should we consider?

A

chronic myloid leukimia