Week 2 GI workbook part 1 Flashcards
where does the foregut run from and to?
esophagus to the duodenum
where does the midgut run from and to?
runs from the liver bud to the junction between the right two thirds and left third of the transverse colon
where does the hindgut run to and from?
left third of transverse colon to the cloacal membrane .
what does the small intestine include?
duodenum, jejunum, ileum
what does the large intestine include?
caecum, appendix and the colon (ascending, transverse, descending, sigmoid)
how long is the muscular tube of the oesophagus?
25cm long
how long is the abdominal part of the oesophagus?
1.25cm
what are the three constrictions of the oesophagus?
cervical, thoracic and diaphragmatic
in which mediasteinum is the oesophagus located?
superior mediasteinum
what is the vertebral level of the oesophageal opening?
T10
what are the structures that pass through the diaphragm at the oesophageal opening?
Oesophagus
IVC
vagus nerves
descending aorta
blood supply of the abdominal oesophagus?
left gastric artery (branch of the celiac trunk) and left inferior phrenic artery
what is the venous drainage of the abdominal oesophagus?
mixed drainage via two roots;
to portal circulation via left gastric vein
to systemic circulation via azygous vein
forms a portosystemic anastomosis
what is the lymphatic drainage of the abdominal oesophagus?
The lymphatic drainage of the oesophagus is divided into thirds:
Superior third – deep cervical lymph nodes.
Middle third – superior and posterior mediastinal nodes.
Lower third – left gastric and celiac nodes.
what occurs to portosystemic anastomoses in portal hypertension?
the anastomoses open and forms venous dilatations called oesophageal varices, their rupture causes severe and dangerous haematemesis
what is the stomach?
muscular bag forming the widest and most distensible part of the digestive tube.
where does the lesser omentum extend from and to?
from lesser curvature to the liver
where does the greater omentum spread from and to?
greater curvature to transverse colon
What is the pyloric sphincter?
Movement of partially digested food (chyme) through the pyloric orifice is controlled by a valve, the pyloric sphincter.
what is the pyloric orifice?
The distal opening of the stomach, into the small intestine, is called the pyloric orifice.
what is the function of the pyloric sphincter?
The pyloric sphincter is formed by a thick circular layer of smooth muscle. Its activity is under autonomic nervous system control. Relaxation of the pyloric sphincter to allow emptying of the stomach contents into the duodenum occurs by action of the parasympathetic nervous system (Cranial nerve 10: Vagus nerve). Constriction of the pylorus and its sphincter is controlled by sympathetic innervation from the celiac ganglion (greater and lesser splanchnic nerves).
what is pyloric stenosis?
narrowing of the opening from the stomach to the first part of the small intestine (pylorus)
symptoms include projectile vomiting without the presence of bile
What are the gastric folds/rugae formed from?
The mucosa has a wrinkled aspect, consisting of ridges called gastric folds, or rugae. During distension of the organ, the gastric folds disappear. Along the lesser curvature of the stomach, a temporary, continuous furrow called gastric canal is formed between the gastric folds. This facilitates the passage of saliva and fluids during swallowing.
In which parts of the stomach are gastric folds/rugae most apparent?
greater curvature
what are the three branches of the celiac trunk?
left gastric, splenic, common hepatic arteries , ,
where does the left gastric vein drain into?
hepatic portal vein
where does the right gastric vein drain into?
hepatic portal vein
where does the left gastriepiploic vein drain into?
first the splennic vein then the hepatic portal vein
where does the right gastroepiploic vein drain to?
superior mesenteric vein then to hepatic portal vein
where does all the lymph fluid from the greater and lesser curvatures of the stomach travel to?
Lymph fluid drains into the gastric and gastro-omental lymph nodes found at the curvatures.
Efferent lymphatic vessels from these nodes connect to the coeliac lymph nodes, located on the posterior abdominal wall.
what lymph nodes drain the cardia of the stomach?
The cardia of the stomach is drained by the juxtacardial lymph nodes,
what lymph nodes drain the fundus of the stomach?
the fundus by the short gastric nodes
what lymph nodes drain the pyloric part of the stomach?
pyloric part by the pyloric lymph nodes (suprapyloric, retropyloric, subpyloric nodes).
where do all the respective lymph nodes of the stomach drain to?
Subsequently, lymph from these nodes empties into the celiac lymph nodes (located around the celiac trunk), which then flows through the intestinal lymphatic trunk into the thoracic duct via the cisterna chyli.
where does the parasympathetic nerve supply of the stomach come from?
Parasympathetic nerve supply arises from the anterior and posterior vagal trunks, derived from the vagus nerve.
where does the sympathetic nerve supply of the stomach come from?
Sympathetic nerve supply arises from the T6-T9 spinal cord segments and passes to the coeliac plexus via the greater splanchnic nerve. It also carries some pain transmitting fibres.
what is the effect of increased vagal stimulation on the pylorus and gastric secretion?
Vagus nerve stimulation significantly accelerated gastric emptying by promoting the relaxation of the pyloric sphincter
what procedure is used to treat over-active acid secretion?
vagotomy
what does a vagotomy do?
denervates the fundus and body, decreasing secretion while the supply to the antrum remains so preserving essential gastric motility
what is the duodenum?
The duodenum is the C shaped structure which continues from the pyloric sphincter of the stomach. The duodenum is the first part of the small intestine. It runs from the pylorus of the stomach to the duodenojejunal junction
how many parts does the duodenum have?
superior, descending, inferior and ascending
What organ sits within the C shape of the duodenum?
head of the pancreas
How is the duodenum peritonised?
Initial 3cm of the superior duodenum is covered anteriorly and posteriorly by visceral peritoneum, with the remainder retroperitoneal (only covered anteriorly)
There is a small opening in the duodenum where pancreatic and bile fluids enter the gut tube. What is this opening called?
major duodenal papilla (papilla of Vater)
What two structures come together at this opening (papilla of Vater)?
common bile duct
pancreatic duct
What is the sphincter that controls the opening (papilla of vater) called?
sphincter of oddi
describe the first section of the duodenum?
D1 – Superior (Spinal level L1)
The first section of the duodenum is known as ‘the cap’. It ascends upwards from the pylorus of the stomach, and is connected to the liver by the hepatoduodenal ligament. This area is most common site of duodenal ulceration.
The initial 3cm of the superior duodenum is covered anteriorly and posteriorly by visceral peritoneum, with the remainder retroperitoneal (only covered anteriorly).
describe the second portion of the duodenum?
D2 – Descending (L1-L3)
The descending portion curves inferiorly around the head of the pancreas. It lies posteriorly to the transverse colon, and anterior to the right kidney.
Internally, the descending duodenum is marked by the major duodenal papilla – the opening at which bile and pancreatic secretions to enter from the ampulla of Vater (hepatopancreatic ampulla).
describe the third portion of the duodenum?
D3 – Inferior (L3)
The inferior duodenum travels laterally to the left, crossing over the inferior vena cava and aorta. It is located inferiorly to the pancreas, and posteriorly to the superior mesenteric artery and vein
describe the fourth portion of the duodenum?
D4 – Ascending (L3-L2)
After the duodenum crosses the aorta, it ascends and curves anteriorly to join the jejunum at a sharp turn known as the duodenojejunal flexure.
Located at the duodenojejunal junction is a slip of muscle called the suspensory muscle of the duodenum. Contraction of this muscle widens the angle of the flexure, and aids movement of the intestinal contents into the jejunum.
what is the minor papillae?
opening for the accessory pancreatic duct. It consists of: the accessory pancreatic duct; pancreatic tissue of the dorsal pancreas, which penetrate the muscularis propria of the duodenum; and the surrounding fibrous connective tissue.