Week 2 Gastrointestinal Drugs

Question 1

generic for Colace

Answer 1

docusate

Question 2

generic for Miralax

Answer 2

polyethylene glycol

Question 3

generic for Senokot

Answer 3

senna

Question 4

generic for Pepcid AC

Answer 4

famotidine

Question 5

generic for Nexium

Answer 5

esomeprazole

Question 6

generic for Prilosec

Answer 6

omeprazole

Question 7

generic for Protonix

Answer 7

pantoprazole

Question 8

generic for Carafate

Answer 8

sucralfate

Question 9

generic for Zofran

Answer 9

ondansetron

Question 10

generic for Phenergan

Answer 10

promethazine

Question 11

generic for Bentyl

Answer 11

dicyclomine

Question 12

pharmacologic class for docusate

Answer 12

stool softener

Question 13

FDA indication(s) for docusate

Answer 13

constipation

Question 14

contraindication(s) for docusate

Answer 14

Avoid OTC use in patient’s experiencing symptoms consistent with bowel obstruction

Question 15

adverse effects for docusate

Answer 15

abdominal cramps and diarrhea

Question 16

monitoring for docusate

Answer 16

bowel movements

Question 17

pharmacologic class for polyethylene glycol

Answer 17

osmotic laxative

Question 18

FDA indication(s) for polyethylene glycol

Answer 18

constipation

Question 19

contraindication(s) for polyethylene glycol

Answer 19

bowel obstruction

Question 20

adverse effects of polyethylene glycol

Answer 20

diarrhea, flatulence, nausea, abdominal pain, electrolyte imbalance (long-term or frequent use)

Question 21

monitoring for polyethylene glycol

Answer 21

bowel movements

Question 22

pharmacologic class for senna

Answer 22

stimulant laxative

Question 23

FDA indication(s) for senna

Answer 23

constipation

Question 24

contraindication(s) for senna

Answer 24

bowel obstruction, GI bleeding

Question 25

adverse effects of senna

Answer 25

Abdominal cramps, diarrhea, nausea, vomiting

Question 26

monitoring for senna

Answer 26

bowel movements

Question 27

pharmacologic class for famotidine

Answer 27

Histamine H2 Antagonist (H2 blocker)

Question 28

FDA indication(s) for famotidine

Answer 28

heartburn, GERD

Question 29

adverse effects of famotidine

Answer 29

Agitation (pediatric), headache, diarrhea, constipation

Question 30

monitoring for famotidine

Answer 30

heartburn

Question 31

pharmacologic class for esomeprazole

Answer 31

Proton pump inhibitor (PPI)

Question 32

FDA indication(s) for esomeprazole

Answer 32

Heartburn, GERD, Peptic Ulcer Disease, NSAID-induced Ulcer Prophylaxis

Question 33

adverse effects of esomeprazole

Answer 33

Abdominal pain, constipation, diarrhea, headache, vitamin B12 deficiency (long-term AE), hypomagnesemia (long-term AE), increased risk C. difficile infection

Question 34

monitoring for esomeprazole

Answer 34

Symptoms, vitamin B12 & magnesium with long term use

Question 35

pharmacologic class for omeprazole

Answer 35

Proton pump inhibitor (PPI)

Question 36

FDA indication(s) for omeprazole

Answer 36

Heartburn, GERD, Zollinger-Ellizon Syndrome (hypersecretory condition)

Question 37

adverse effects of omeprazole

Answer 37

Abdominal pain, constipation, diarrhea, headache, vitamin B12 deficiency (long-term AE), hypomagnesemia (long-term AE), increased risk C. difficile infection

Question 38

monitoring for omeprazole

Answer 38

Symptoms, vitamin B12 & magnesium with long term use

Question 39

pharmacologic class for pantoprazole

Answer 39

Proton pump inhibitor (PPI)

Question 40

FDA indication(s) for pantoprazole

Answer 40

GERD, Zollinger-Ellison Syndrome (hypersecretory condition)

Question 41

adverse effects of pantoprazole

Answer 41

Abdominal pain, constipation, diarrhea, headache, vitamin B12 deficiency (long-term AE), hypomagnesemia (long-term AE), increased risk C. difficile infection

Question 42

monitoring for pantoprazole

Answer 42

Symptoms, vitamin B12 & magnesium with long term use

Question 43

pharmacologic class for sucralfate

Answer 43

gastrointestinal agent

Question 44

FDA indication(s) for sucralfate

Answer 44

Ulcer Treatment & Prophylaxis

Question 45

adverse effects of sucralfate

Answer 45

Constipation, Aluminum accumulation in patients with renal failure or on dialysis

Question 46

pharmacologic class for ondansetron

Answer 46

Serotonin (5HT3) Receptor Antagonist

Question 47

FDA indication(s) for ondansetron

Answer 47

Cancer chemotherapy-induced nausea and vomiting, postoperative nausea and vomiting, radiotherapy-associated nausea and vomiting

Question 48

adverse effects of ondansetron

Answer 48

Headache, fatigue, constipation, QT prolongation, Serotonin Syndrome

Question 49

pharmacologic class for promethazine

Answer 49

First Generation Histamine Antagonist

Question 50

FDA indication(s) for promethazine

Answer 50

Allergic conditions, nausea and vomiting, motion sickness, sedation

Question 51

contraindication(s) for promethazine

Answer 51

Concomitant use with MAO inhibitors, Asthma, Use in children under <2 due to respiratory depression

Question 51

black box warning for promethazine

Answer 51

Risk of fatal respiratory depression in pediatric patients < 2 years of age. Injectable promethazine can cause severe chemical irritation and damage to tisses.

Question 52

adverse effects of promethazine

Answer 52

Orthostatic hypotension, akathisia, drowsiness, photosensitivity, anticholinergic effects, extrapyramidal symptoms

Question 53

monitoring for promethazine

Answer 53

Signs/symptoms of abnormal movements, signs/symptoms of excessive sedation and/or respiratory depression

Question 54

pharmacologic class of dicyclomine

Answer 54

anticholinergic agent

Question 55

FDA indication(s) for dicyclomine

Answer 55

Irritable Bowel Syndrome (IBS)

Question 56

contraindication(s) for dicyclomine

Answer 56

GI obstruction, Glaucoma, Age <6 months

Question 57

adverse effects of dicyclomine

Answer 57

Dizziness, xerostomia, nausea, blurred vision, drowsiness, nervousness

Question 58

monitoring for dicyclomine

Answer 58

Signs/symptoms of muscle weakness