Week 2: Anthillpemic/ Antianginal drugs

Question 1

The most potent drug available for reducing plasma lipid concentrations.

Answer 1

Statin’s are used to reduce plasma lipid concentrations

Question 2

How long does it take Statin’s to start working?

Answer 2

Statins usually take 6-8 weeks to have their optimal effect on the body

Question 3

What is the action of Statin drugs?

Answer 3

Statin drugs help lower the amount of cholesterol in the body by decreasing its production in the liver

Question 4

What specific enzyme does Statin inhibit?

Answer 4

Statin inhibits the HMG-CoA reductase, which is a hepatic enzyme responsible for cholesterol production

Question 5

What is the action of bile acid sequenstrants?

Answer 5

bile acid sequenstrants lower the body cholesterol by increasing volumes of bile acid production

Question 6

What are common side effects of bile acid sequenstrants?

Answer 6

A common side effect of bile acid sequenstrants is gastric upset

Question 7

What is the action of Fibric Acid Derivatives (Fibrates)?

Answer 7

Fibric acid derivatives, or Fibrates, primarily effect body triglyceride levels, they also lower cholesterol.

Question 8

What are the three main types of drugs used to treat angina?

Answer 8

The three main types of drugs to treat angina are:

Nitrates
Beta blockers
Calcium channel blockers

Question 9

This classification of drugs inhibit platelet aggregation by inhibiting cyclooxyrgenase for duration of platelet lifespan and formation of TXA2

Answer 9

anti platelet agents (ASA/aspirin)

Question 10

This classification of drugs promote vasodilation as a result of relaxing smooth muscle cells in the wall structure of veins and arteries, decreased preload and after load

Answer 10

short acting nitrates

Question 11

This classification of drugs alter/inhibit platelet membrane receptors so it can no longer receive the fibrinogen signal to aggregate and form clots

Answer 11

adenosine diphosphate inhibitor

Question 12

This classification of drug lower the rate of cholesterol production in the liver

Answer 12

antiilpemic drugs

Question 13

This classification of drug blocks receptor sites sensitive to epinephrine in heart conduction system and myocardium, decreases energy demand on heart, reduces heart rate

Answer 13

beta blockers

Question 14

This classification of drug prevents calcium into entry into the heart excitation-contraction coupling process

Answer 14

calcium channel blocking agents

Question 15

What are the nursing considerations for antilipemic drugs?

Answer 15

• cause transient GI disturbances, rashes, headaches
• constpiation

take in evening with meal and water to minimize GI upset

Question 16

Concurrent use of nitrates with these drugs can be serious and potential hypotension.

Answer 16

viagra
tadalafil
vardenafil
phosphodiesterase type 5 inhibitor (used for erectile dysfunction)