week 2: Angle closure Flashcards

1
Q

T/F: the iris rests on the lens?

A

False, there is about a 5 um space bw them

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2
Q

what is relative pupillary block?

A

flow of aqueous from the posterior chamber through the pupil is impeded (blockage in path bw iris and lens) and obstruction creates a pressure gradient between the posterior and anterior chambers, causing the peripheral iris to bow forward against the trabecular meshwork

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3
Q

Risk factors for relative pupillary block? (or just angle closure?)

A

1) older age:60-70
2) women (have shallower ACs)-except for african americans
3) fam hx
4) hyperopic eyes
5) small cornea and winter (low light)

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4
Q

avg adult eye chamber depth:

A
  1. 15 mm

* at risk for closure if 2.0 mm or less

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5
Q

T/F: pupillary block can frequently happen not immediately after dilation but later when drops are wearing off and the pupil is mid dilation

A

true

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6
Q

4 categories of angle closure:

A

1) primary angle closure suspect
2) primary angle closure
3) primary angle closure glaucoma
4) acute angle crisis glaucoma

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7
Q

what classifies someone as primary angle closure suspect:

A

180 degrees or more of iridotrabecular contact on gonio in primary gaze (IOP is normal, optic nerve normal, no PAS)

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8
Q

what classifies someone as primary angle closure vs just a suspect:

A

180 degrees or more of iridotrabecular contact on gonio in primary gaze but there is harm being done to eye normal nerves and field but PAS and or elevated IOP

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9
Q

what classifies someone as primary angle closure glaucoma vs just a PAC:

A

180 degrees or more of iridotrabecular contact on gonio in primary gaze but there is harm being done to eye: glaucomatous fields and nerves

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10
Q

outcome so far of ZAP study:

A

LPI done in one eye is effective but only for about 6 months (but still better than no LPI in fellow eye)

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11
Q

in acute angle closure glaucoma, pupils will be:

A

mid dilated

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12
Q

describe the AC depth, angle depth and bilaterality of Pupil Block

A

narrow angle, shallow axial depth, bilateral, iris bombe (bows)

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13
Q

describe the AC depth, angle depth and bilaterality of plateau iris:

A

narrow angle, depth relatively normal, bilateral, plateau appearance on gonio

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14
Q

describe the AC depth, angle depth and bilaterality of malignant

A

flat chamber, narrow angle, unilateral

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15
Q

which laser do you use for LPI?

A

YAG works better for light eyes, but most docs just do both (argon then YAG)

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16
Q

what 3 gtts do you give pre LPI?

A

proparacaine
pilo
apraclonidine or brimonidine (to avoid IOP spike after)

17
Q

what gtt do you give after LPI?

A

pred forte 4X a day for several days (+glaucoma meds if they need or take them)

18
Q

what is glaukomflecken?

A

infarction of ant lens epithelium from high IOP

19
Q

name 3 examples in the eye that indicate previous angle closure attacks:

A

1) peripheral ant synechiae
2) glaukomflecken
3) iris atrophy

20
Q

what is subacute angle closure glaucoma?

A

older classification: subacute/intermittent
Recurrent attacks- small
Dim lighting leads to pupil dilation and block
-PAS, particularly superiorly
-IOP often normal in office but angle very narrow

21
Q

what kind of questions should you ask someone you suspect has subacute angle closure?

A

Blurred vision, halos around lights, eye pain, HA, eye redness

22
Q

most common type of primary angle closure?

23
Q

what symptoms do you get with chronic primary angle closure?

A

asymptomatic

24
Q

2 types of plateau iris:

A

1) plateau iris configuration

2) plateau iris syndrome

25
T/F: having an LPI makes you more prone to cataract?
true: After LPI about 1/3 of patients develop a cataract
26
plateau iris configuration:
anteriorly displaced peripheral iris compromising the angle (anatomic) DESPITE deep AC
27
plateau iris syndrome:
development of angle closure either spontaneously or after dilation in patent LPI
28
iris bombe:
apposition of the iris to the lens or anterior vitreous, preventing aqueous from flowing from the posterior to the anterior chamber
29
plateau iris more common in:
women
30
how do you treat someone with plateau iris?
only tx if high IOP, maybe miotics (at night), gonioplasty
31
what is gonioplasty?
- used to constrict the peripheral iris pulling it away from the angle - go to the stroma and NOT all the way through - small holes in iris near limbus
32
complications of gonioplasty/iridoplasty?
o Corneal burns o Marked anterior chamber inflammation o Corneal endothelial cell damage
33
what is happening in malignant glaucoma?
lens, ciliary body, iris all move forward - ciliary-lenticular blockage causing the CB to move toward the lens causing aqueous to become trapped in vitreous increasing vitreous volume - choroidal swelling
34
Name some associated causes of malignant glaucoma
``` CB swelling (scleritis), CRVO, S/P PRP, Sulfa drugs, cataract surgery -Tobramax/Topiramate- medicine used that can cause bilateral malignant glaucoma ```
35
how to tx malignant glaucoma
atropine, steroids, aqueous suppressors d/c meds that caused it maybe try LPI
36
list a few causes of NVI
CRVO ocular ischemia diabteic ret (prolif)
37
tx of NVI
PRP and anti VEGF