Week 2 Flashcards

1
Q

Is the heat response vasoconstriction or vasodilation?

A

Vasodilatoin

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2
Q

Is the cold response vasoconstriction or vasodilation?

A

Vasoconstriction; decreased sweating, shivering

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3
Q

What skin disorder is caused by Chediak-Higashi Syndrome?

A

Albinism (tyrosine mutation)

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4
Q

Pemphigus Vulgaris: IgG autoantibodies against ____

A

Desmoglein 3

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5
Q

Where does fluid accumulate in pemphigus vulgaris?

A

Above basal layer

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6
Q

Bullous Pemphiogoid: IgG autoantibodies against _____

A

Hemidesmosomes

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7
Q

Where does fluid accumulate in Bullous Pemphigoid?

A

Between epidermis and basement membrane

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8
Q

Nikolsky sign is positive in ___ and negative in ____.

A

P. vulgaris; b. pemphigoid

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9
Q

Which skin disorder is associated with celiac disease?

A

Dermatitis Herpetiformis

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10
Q

Guarnieri bodies are associated with _____.

A

Smallpox (variola)

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11
Q

A “pearl-like” skin lesion is most likely referring to which disease?

A

Molluscum contagiosum

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12
Q

What are Tzanck smears used for?

A

Diagnosing active herpes infection

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13
Q

Fifth Disease is associated with ______

A

Parvo B19 virus

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14
Q

Which disease is this: after fever, rash starts on trunks then spreads to extremities

A

Roseola

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15
Q

Hand, foot, and mouth disease is caused by which virus

A

Cocksackievirus (Picornavirus – enterovirus (naked +ssRNA)

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16
Q

A rash commonly appears on hands and soles of feet in ______.

A

Treponema Pallidum

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17
Q
Name the disease: Centripetal rash -appears first on
the wrists and ankles, often
spreading within hours
proximally to the trunk and
distally to the palms and soles
A

Rocky Mountain Spotted Fever

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18
Q

What is the most common cervical radiculopathy?

A

C7 radiculopathy

19
Q

C4 dermatome:

A

skin over the shoulder tip

20
Q

C5 dermatome:

A

upper lateral arm

21
Q

C6 dermatome:

A

thumb

22
Q

C7 dermatome:

A

index finger

23
Q

C8 dermatome:

A

little finger

24
Q

T1 dermatome

A

medial elbow

25
Q

T2 dermatome

A

skin of axilla

26
Q

C5 myotome:

A

shoulder abduction

27
Q

C6 myotome:

A

elbox flexion

28
Q

C7 myotome:

A

elbow extension

29
Q

C8 myotome:

A

flexion of fingers

30
Q

T1 myotome:

A

abduction and adduction of fingers

31
Q

what are the terminal branches of the brachial plexus?

A

Musculocutaneous nerve, axillary nerve, radial nerve, median nerve, ulnar nerve

32
Q

Describe Erb-Duchenne paralysis (waiter’s tip)

A

adducted shoulder, extended elbow, internally rotated arm)

33
Q

which nerves are affected in Erb-Duchenne paralysis?

A

axillary (deltoid abduction), musculocutaneous (biceps flexion), suprascapular nerve (infraspinatus external rotation)

34
Q

which nerves are involved in Klumpke paralysis?

A

radial and ulnar

35
Q

In Pemphigus Vulgaris, Abs are directed against _______.

A

Desmoglein 3

36
Q

In Kawasaki Disease, Abs are directed against _____.

A

Blood vessels

37
Q

In immune-mediated thrombocytopenia, Abs are directed against

A

platelets.

38
Q

Kawaski disease most commonly occurs after _____ in _____ children.

A

infection; genetically disposed

39
Q

Serum sickness: deposition of immune complexes in _____.

A

tissue

40
Q

Arthus reaction: deposition of immune complexes in ______.

A

skin

41
Q

morbiliform rash on the face is likely due to _____

A

Steven Johnsons

42
Q

morbiliform rash on the trunk is likely due to ______

A

DRESS syndrome

43
Q

white dots or lines known as Wickham striae are seen in which condition?

A

lichen planus