Week 2 Flashcards
Is the heat response vasoconstriction or vasodilation?
Vasodilatoin
Is the cold response vasoconstriction or vasodilation?
Vasoconstriction; decreased sweating, shivering
What skin disorder is caused by Chediak-Higashi Syndrome?
Albinism (tyrosine mutation)
Pemphigus Vulgaris: IgG autoantibodies against ____
Desmoglein 3
Where does fluid accumulate in pemphigus vulgaris?
Above basal layer
Bullous Pemphiogoid: IgG autoantibodies against _____
Hemidesmosomes
Where does fluid accumulate in Bullous Pemphigoid?
Between epidermis and basement membrane
Nikolsky sign is positive in ___ and negative in ____.
P. vulgaris; b. pemphigoid
Which skin disorder is associated with celiac disease?
Dermatitis Herpetiformis
Guarnieri bodies are associated with _____.
Smallpox (variola)
A “pearl-like” skin lesion is most likely referring to which disease?
Molluscum contagiosum
What are Tzanck smears used for?
Diagnosing active herpes infection
Fifth Disease is associated with ______
Parvo B19 virus
Which disease is this: after fever, rash starts on trunks then spreads to extremities
Roseola
Hand, foot, and mouth disease is caused by which virus
Cocksackievirus (Picornavirus – enterovirus (naked +ssRNA)
A rash commonly appears on hands and soles of feet in ______.
Treponema Pallidum
Name the disease: Centripetal rash -appears first on the wrists and ankles, often spreading within hours proximally to the trunk and distally to the palms and soles
Rocky Mountain Spotted Fever