Week 2 Flashcards
How many alcohol related deaths are there per year?
3 million. 6 deaths a minute
What percentage of deaths are related to alcohol
5.3%
How many disease conditions is alcohol a causal factor in?
200
What is the Volstead Act?
Implemented the 18th amendment which prohibited the manufacture and sale of alcoholic beverages.
What is the 21st Amendment
Repealed the 18th amendment
What is the FDA
They are the food and drug administration. They are the regulatory authority of the safety of the food and drug industry.
What is the DEA
Drug Enforcement Agency. They enforce the controlled substance laws and regulations in the US.
What is the Harrison Act 1914
Restricted the sale of Opium and Cocaine to those who were licensed. Treatment for addiction was declared outside of scope using these drugs.
Schedule 1 Drugs
High potential for abuse. No accepted medical use. lack of accepted safety for use.
What drugs are in schedule 1
heroin, hallucinogens (LSD, Ibogaine, peyote), Marijuana.
What is schedule 2
High potential for abuse but has a current accepted medical use in the US or medical use with severe restrictions. abuse may lead to dependence.
What drugs are in schedule 2
fentanyl, hydrocodone, oxycodone, methadone, morphine, codeine, cocaine, amphetamine, methamphetamine, ritalin.
What is schedule 3
Drug has potential for abuse less than schedule 2. Currently accepted as a medical treatment in the US. Abuse may lead to moderate or low physical dependence or high dependence.
What drugs are in schedule 3
nalorphine, tylenol with codeine, buprenorphine, phencyclidine, anabolic steroids
What is schedule 4
Drug has low potential for abuse relative to those in schedule 3. accepted medical use treatment. Abuse may lead to limited dependence relative to schedule 3.
What is schedule 5
Low potential for abuse relative to schedule 4. currently accepted medical use. abuse may lead to limited dependence or psychological dependence relative to schedule 4 drugs.
Where does Marijuana Stand now?
Still a schedule 1 drug but 33 states and DC have either legalized or partially legalized its use. Physicians cannot dispense it.
What is pharmacokinetics
The study of plasma concentration of drugs and all of the factors that affect those concentrations.
What factors of pharmacokinetics affect concentration?
absorption, bioavailability, distribution, protein binding, metabolism, excretion/Clearance and half life.
What is pharmacodynamis
What the drug does to the body. Actual mechanisms of action that lead to the effect the drug has on the body.
Define Absorbtion
rate that the drug leaves its site of administration and enters the bloodstream.
define bioavailability
The extent to which a drug is actually available at the ultimate site of action.
Define Drug Distribution
Where the drug goes in the blood.
What is protein binding
Many drugs are protein bound and this affects how they are distributed.
