Week 2 Flashcards

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1
Q

What are the 4 main types of Ions?

A

Sodium
Potassium
Chloride
Organic Anions

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2
Q

What does Cl- stand for?

A

Chloride (Cl-)

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3
Q

What does Na+ stand for?

A

Sodium (Na+)

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4
Q

During the resting state, is a neuron pos or neg charged?

A

Negatively

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5
Q

What does K+ stand for?

A

Potassium (K+)

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6
Q

As an atom positively or neg charged?

A

no, it’s neutral. When it stops being neutral it becomes and Ion (pos OR neg charged)

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7
Q

What does A- Stand for?

A

Organic Anions (A-)

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8
Q

What is the shorthand for Sodium?

A

Na+

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9
Q

What is the shorthand for potassium?

A

K+

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10
Q

What is an Ion?

A

pos or neg charged Atom

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11
Q

What is shorthand for Organic Anions?

A

A-

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12
Q

What is shorthand for Chloride?

A

Cl-

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13
Q

Where do the pos & negative electrons and protons sit in an atom?

A

Positive Protons inside nucleus

Neg Electron orbit around nucleus in outer shell

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14
Q

Is an electron pos or neg?

A

neg

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15
Q

is a proton pos or neg?

A

pos

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16
Q

Is an atom pos or neg charged?

A

Neither, it’s neutral - pos & neg even each other out so in resting state it remains neutral

17
Q

what is an ion?

A

pos or neg charged atom

18
Q

how does an ion become negatively charged?

A

gaines neg electron

19
Q

How is the resting potential maintained?

A

Ion channels

allows inflow of ions in and out of cell

Sodium-Potassium pump

20
Q

Where are receptors found?

A

Mostly Cell Body & Dendrites

21
Q

In analogy of lock and key, receptors are one and key is the other. Which is the Receptor?

A

Receptor is key

22
Q

What do autoreceptors do?

A

Turn off neurotransmitter release (stimulated neurotransmitters released by own neuron)

23
Q

What is the GABBA-A neurotransmitter?

A

Main inhibitory

24
Q

What is an Antagonist?

A

A drug that opposes or inhibits the effects of a particular neurotransmitter on the postsynaptic cell

25
Q

What is an Agonist?

A

A drug that facilitates the effects of a particular neurotransmitter on the postsynaptic cell

26
Q

Which drug action imitates a neurotransmitter?

A

Agonist

27
Q

What is a direct antagonist?

A

A drug that binds with receptor but does not activate it - prevents the natural ligand from binding with the receptor. Stops natural action

28
Q

what is a direct agonist?

A

A drug that binds with and activated receptor - just as the neurotransmitter would

29
Q

What is non-competitive binding on a receptor?

A

Binding of a drug to a site on a receptor; does not interfere with the binding site for the principal ligand.

30
Q

What is an indirect agoinst?

A

A drug that attaches to a binding site on a receptor and facilitates the action of the receptor; does not interfere with the binding site of the principal ligand.

31
Q

What is an indirect antagonist?

A

A drug that attaches to a binding site on a receptor and interferes with the action of the receptor; does not interfere with the binding of the principal ligand.

32
Q

What is a resting membrane potential?

A

resting potential

33
Q

How does an atom become a neg charged ion?

A

gains a negative charged electron

34
Q

how doe an atom become a pos charged ion?

A

looses a neg charged electron

35
Q

what is a excitatory postsynaptic potential (EPSP)?

A

if stimulations causes the voltage inside of the cell to become more positive (keep firing)

36
Q

what is a Inhibitory postsynaptic potential (IPSP)?

A

if stimulations causes the voltage inside of the cell to become more negative (stop firing)

37
Q

neurotransmitters cant be left in the gap as they will continue to exert effect or block receptor. What is the Reuptake pump?

A

physical removal of neurotransmitter - directs it back into presynaptic neuron for recycling

38
Q

neurotransmitters cant be left in the gap as they will continue to exert effect or block receptor. What is an Exzymatic degredation?

A

Enzymes break down neurotransmitters

no longer fire

39
Q

Where are receptors mostly found?

A

dendrites & cell body