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Dermatology > Week 2 > Flashcards

Week 2 Flashcards

1
Q

Domed Papule with a keratin filled center (Volcanic Appearance)
- Tx:

A

Keratoacanthoma

  • Surgical excision
  • Progresses quickly, similar looking to SCC
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2
Q

Benin capillary hemangioma, very friable, glistening red papule

A

Pyogenic granuloma, friable looking.

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3
Q

Non-scaling, ropy border, central clearing. Looks a little like tinea corporis but without the scaling.. (picture of foot)

A

Granuloma annulare

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4
Q

Targetoid rash, associated with tick bites

  • Microbio bug
  • Skin condition
  • Tx
A
  • Borrelia Burgdorferi
  • Erthema MIGRANTS
  • Can continue to lyme disease with bilateral bells palsy, etc.
  • Tx: Amoxicillin or doxycycline
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5
Q

Erythema nodosum

- Microbio bug

A

Streptococcal infection is common, also seen with fungal infections (sketchy = specifically the systemic ones such as histoplasmosis, blastomycosis, coccidiomycosis, paracoccidiomycosis)
- On the shins!

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6
Q

Cancer with red scaly patch, central ulceration (umbilication) and PEARLY border

A

Basal Cell Carcinoma!

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7
Q

Skin cancer associated with smoking and therefore can present with cancer of the lip

A

Squamous Cell Carcinoma

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8
Q

3 types of basal cell carcinoma

- Nodular, Superficial, and Morpheaform

A

Nodular = nodular. Blah.

Superficial = flat, pink, etc.

Morpheaform = high rate of recurrence, overlying telangectasia

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9
Q

BCC: Which epidermal layer?

A

Basal layer

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10
Q

Best treatment option for high risk areas like Face, eyes, and ears.

A

Mohs

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11
Q

“Stuck on” lesions, looks like you can just peel it off

A

Seborrheic Keratoses

  • AKA basal cell papilloma or verruca senilis
  • cystic inclusions of HORNY material (keratin horns)
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12
Q

Benign Neoplasm that is centrally umbilicated. Crater is lined by glassy, proliferating keratinocytes that invade the dermis

A

Keratoacanthoma

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13
Q

Pre Squamous Cell Carcinoma

2

A

AK - Actinic (solar) Keratosis
- Scaly erythematous patches and plaques. Hyperchromatic nuclei.

Leukoplakia
- Associated by EBV and HIV

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14
Q

Pearly papule, will see basophilic cells on histology

A

Basal Cell Carcinoma

  • Most common malignant tumor
  • Cancer of the basal layer
  • Cubodial epithelium
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15
Q

Cancer of the epidermis whose cells typically resemble keratinocytes.

A

Squamous Cell Carcinoma

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16
Q

Most common cancer in men of India

A

Oral Squamous Carcinoma

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17
Q

Skin condition seen in Insulin resistance as well as several internal malignancies.
- What is the treatment

A

Acanthosis Nigricans

- Treat underlying cause!

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18
Q

Treatment for verrucae

A

Warts, caused by HPV

- Salicylic acid is first line (liquid nitrogen too which is also used for seborrheic keratosis

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19
Q

Medical term for skin tags

A

acrdochordons

20
Q

Umbilicated PAPULES that are NEVER found on the palms or soles.

A

Molluscum Contagiosum (part of pox virus family)

21
Q

yellow cholesterol plaque present on eyelids

- Associated with familial _____

A

Xanthelasma, associated with hyperlipidemia

22
Q

Generalized Papules and Plaques: two of the Cutaneous T-Cell Lymphoma

A

Mycosis Fungoides and Sezary syndrome

23
Q
  • Mycosis fungoides, will see _______ on biopsy

- Sezary Syndrome

A
  • Mycosis Fungoides: atypical mononuclear cells invading upper epidermis (because it is a T-cell lympoma)
  • Sezary syndrome: Circulating Sezary cells (atypical lymphocytes with cerebriform nuclei)
24
Q

Associated with Wickham’s striae (buzzword)

- Associated with Hep C

A

Lichen Planus

  • White, lacelike pattern on the surface of the lesions or in the oral mucosa
  • Associated with Hep C
25
Characteristics Lichen Planus
5 Ps = Pruritic, purple, planar, polygonal, and papules
26
Sarcoidosis: will see __________ in biopsy
noncaseating granulomas | - It is a granulomatous disease that affects many organs, under 40, and more common in African-American
27
Salmon colored plaques with a silvery scale on extensor surfaces =
Psoriasis | - Will see elongation of rete ridges and dermal papillae
28
Psoriasis: Clinical presentation (two specific presentations) + one rare presentation
Koebner phenomenon = lesions in sites of trauma from scratching (STAR) Auspitz sign = punctate bleeding if scales removed. Note: psoriatic arthritis!
29
Pathogenesis of psoriasis
Autoimmune disease with persistent epidermal hyperplasia = rapidly dividing epidermal (3-4 days vs 28 days)
30
Treatment for pemphigus vulgaris
Systemic steroids => Glucocorticoids
31
Pemphigus vulgaris has a ____________ sign
Postive Nikolsky's sign | - Rubbering periphery of blister and having a separation of skin layers
32
(+) Nikolsky's sign is positive in... (3)
Staph scalded skin syndrome, TEN, Pemphigus Vulgaris
33
Dx of Bullous Pemphigoid + area of separation
Separation: level of basement membrane | - Dx: Biopsy and Immunofluorescent staining with negative Nikolsky's sign
34
Associated with Celiac disease (hence the reason why tx is Gluten Free Diet)
Dermatitis herpetiformis
35
Dermatitis Herpetiformis Tx (2)
Dapsone and Gluten Free Diet
36
Dermatitis Herpetiformis is _____ mediated and located in the _______ dermis.
IgA mediated, and located in the papillary dermis.
37
The pruritic rash you had on your skin
Dyshidrotic Eczema
38
Hot Tub folliculitis is associated with ________
pseudomonas aeruginosa
39
Which autoimmune bullous disorder have IgG antibodies and which one has IgA antibodies
Pemphigus Vulgaris = IgG antibodies against keratinocyte antigen Bullous Pemphigoid = IgG antibodies in the basement membrane Dermatitis Herpetiformis = IgA antibodies in the dermal papillae
40
Autoimmune Bullous Disorders: separation of the entire epidermis at the dermoepidermal junction therefore doesn't rupture easily (tense)
Bullous pemphigoids
41
Autoimmune Bullous Disorders: Oral mucosa is not affected
Dermatitis herpatiformis
42
Anti-Jo-1 antibodies are seen in....
dermatomyositis
43
Associated with Ash leaf spot and the classical triad of seizure, intellectual disability, and favial angiofibromas
Tuberous Sclerosis | - Brain lesions characteristic of TSC = cortical tubers
44
See helitrope rash on the eye lids, Shawl sign around the shoulders, and Gottron's sign over the finger joints...
Dermatomyositis | - Also have Anti-Jo-1 antibodies + proximal muscle weakness
45
What diseases are seen with pretibial subcutaneous nodules (Erythema nodosum)
Ulcerative Colitis and Crohn's + strep infections are common.
46
Has elevated ESR lab value
psoriasis

Dermatology (10 decks)

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