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Dermatology > Week 2 > Flashcards

Week 2 Flashcards

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Dermatology Board Prep flashcards
1
Q

Domed Papule with a keratin filled center (Volcanic Appearance)
- Tx:

A

Keratoacanthoma

  • Surgical excision
  • Progresses quickly, similar looking to SCC
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2
Q

Benin capillary hemangioma, very friable, glistening red papule

A

Pyogenic granuloma, friable looking.

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3
Q

Non-scaling, ropy border, central clearing. Looks a little like tinea corporis but without the scaling.. (picture of foot)

A

Granuloma annulare

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4
Q

Targetoid rash, associated with tick bites

  • Microbio bug
  • Skin condition
  • Tx
A
  • Borrelia Burgdorferi
  • Erthema MIGRANTS
  • Can continue to lyme disease with bilateral bells palsy, etc.
  • Tx: Amoxicillin or doxycycline
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5
Q

Erythema nodosum

- Microbio bug

A

Streptococcal infection is common, also seen with fungal infections (sketchy = specifically the systemic ones such as histoplasmosis, blastomycosis, coccidiomycosis, paracoccidiomycosis)
- On the shins!

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6
Q

Cancer with red scaly patch, central ulceration (umbilication) and PEARLY border

A

Basal Cell Carcinoma!

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7
Q

Skin cancer associated with smoking and therefore can present with cancer of the lip

A

Squamous Cell Carcinoma

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8
Q

3 types of basal cell carcinoma

- Nodular, Superficial, and Morpheaform

A

Nodular = nodular. Blah.

Superficial = flat, pink, etc.

Morpheaform = high rate of recurrence, overlying telangectasia

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9
Q

BCC: Which epidermal layer?

A

Basal layer

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10
Q

Best treatment option for high risk areas like Face, eyes, and ears.

A

Mohs

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11
Q

“Stuck on” lesions, looks like you can just peel it off

A

Seborrheic Keratoses

  • AKA basal cell papilloma or verruca senilis
  • cystic inclusions of HORNY material (keratin horns)
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12
Q

Benign Neoplasm that is centrally umbilicated. Crater is lined by glassy, proliferating keratinocytes that invade the dermis

A

Keratoacanthoma

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13
Q

Pre Squamous Cell Carcinoma

2

A

AK - Actinic (solar) Keratosis
- Scaly erythematous patches and plaques. Hyperchromatic nuclei.

Leukoplakia
- Associated by EBV and HIV

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14
Q

Pearly papule, will see basophilic cells on histology

A

Basal Cell Carcinoma

  • Most common malignant tumor
  • Cancer of the basal layer
  • Cubodial epithelium
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15
Q

Cancer of the epidermis whose cells typically resemble keratinocytes.

A

Squamous Cell Carcinoma

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16
Q

Most common cancer in men of India

A

Oral Squamous Carcinoma

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17
Q

Skin condition seen in Insulin resistance as well as several internal malignancies.
- What is the treatment

A

Acanthosis Nigricans

- Treat underlying cause!

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18
Q

Treatment for verrucae

A

Warts, caused by HPV

- Salicylic acid is first line (liquid nitrogen too which is also used for seborrheic keratosis

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19
Q

Medical term for skin tags

A

acrdochordons

20
Q

Umbilicated PAPULES that are NEVER found on the palms or soles.

A

Molluscum Contagiosum (part of pox virus family)

21
Q

yellow cholesterol plaque present on eyelids

- Associated with familial _____

A

Xanthelasma, associated with hyperlipidemia

22
Q

Generalized Papules and Plaques: two of the Cutaneous T-Cell Lymphoma

A

Mycosis Fungoides and Sezary syndrome

23
Q
  • Mycosis fungoides, will see _______ on biopsy

- Sezary Syndrome

A
  • Mycosis Fungoides: atypical mononuclear cells invading upper epidermis (because it is a T-cell lympoma)
  • Sezary syndrome: Circulating Sezary cells (atypical lymphocytes with cerebriform nuclei)
24
Q

Associated with Wickham’s striae (buzzword)

- Associated with Hep C

A

Lichen Planus

  • White, lacelike pattern on the surface of the lesions or in the oral mucosa
  • Associated with Hep C
25
Q

Characteristics Lichen Planus

A

5 Ps = Pruritic, purple, planar, polygonal, and papules

26
Q

Sarcoidosis: will see __________ in biopsy

A

noncaseating granulomas

- It is a granulomatous disease that affects many organs, under 40, and more common in African-American

27
Q

Salmon colored plaques with a silvery scale on extensor surfaces =

A

Psoriasis

- Will see elongation of rete ridges and dermal papillae

28
Q

Psoriasis: Clinical presentation (two specific presentations) + one rare presentation

A

Koebner phenomenon = lesions in sites of trauma from scratching (STAR)

Auspitz sign = punctate bleeding if scales removed.

Note: psoriatic arthritis!

29
Q

Pathogenesis of psoriasis

A

Autoimmune disease with persistent epidermal hyperplasia = rapidly dividing epidermal (3-4 days vs 28 days)

30
Q

Treatment for pemphigus vulgaris

A

Systemic steroids => Glucocorticoids

31
Q

Pemphigus vulgaris has a ____________ sign

A

Postive Nikolsky’s sign

- Rubbering periphery of blister and having a separation of skin layers

32
Q

(+) Nikolsky’s sign is positive in… (3)

A

Staph scalded skin syndrome, TEN, Pemphigus Vulgaris

33
Q

Dx of Bullous Pemphigoid + area of separation

A

Separation: level of basement membrane

- Dx: Biopsy and Immunofluorescent staining with negative Nikolsky’s sign

34
Q

Associated with Celiac disease (hence the reason why tx is Gluten Free Diet)

A

Dermatitis herpetiformis

35
Q

Dermatitis Herpetiformis Tx (2)

A

Dapsone and Gluten Free Diet

36
Q

Dermatitis Herpetiformis is _____ mediated and located in the _______ dermis.

A

IgA mediated, and located in the papillary dermis.

37
Q

The pruritic rash you had on your skin

A

Dyshidrotic Eczema

38
Q

Hot Tub folliculitis is associated with ________

A

pseudomonas aeruginosa

39
Q

Which autoimmune bullous disorder have IgG antibodies and which one has IgA antibodies

A

Pemphigus Vulgaris = IgG antibodies against keratinocyte antigen

Bullous Pemphigoid = IgG antibodies in the basement membrane

Dermatitis Herpetiformis = IgA antibodies in the dermal papillae

40
Q

Autoimmune Bullous Disorders: separation of the entire epidermis at the dermoepidermal junction therefore doesn’t rupture easily (tense)

A

Bullous pemphigoids

41
Q

Autoimmune Bullous Disorders: Oral mucosa is not affected

A

Dermatitis herpatiformis

42
Q

Anti-Jo-1 antibodies are seen in….

A

dermatomyositis

43
Q

Associated with Ash leaf spot and the classical triad of seizure, intellectual disability, and favial angiofibromas

A

Tuberous Sclerosis

- Brain lesions characteristic of TSC = cortical tubers

44
Q

See helitrope rash on the eye lids, Shawl sign around the shoulders, and Gottron’s sign over the finger joints…

A

Dermatomyositis

- Also have Anti-Jo-1 antibodies + proximal muscle weakness

45
Q

What diseases are seen with pretibial subcutaneous nodules (Erythema nodosum)

A

Ulcerative Colitis and Crohn’s + strep infections are common.

46
Q

Has elevated ESR lab value

A

psoriasis

Dermatology (10 decks)

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