1.07 - Introduction to Pharmacology of the Skin

Question 1

What is important about occlusive dressings

Answer 1

Occlusive dressings increase the absorption and effectiveness of topical therapy. Most common are polyethylene films (transparent)

Question 2

What is significant about intertriginous areas regarding drug absorption

Answer 2

Describes an area where two skin areas may tough or rub together, tend to be moister/thinner skin and therefore have enhanced percutaneous absorption.

Question 3

Solvent thickened with polymers, used for drying and in hairy areas.

Answer 3

Gel

Question 4

Used for LARGE hairy areas and intertriginous areas (prone to occlusion)

Answer 4

Lotion

Question 5

A semi-solid preparations of hydrocarbons with strong emollient effect. Contains no water and does not require a preservative.

Answer 5

Ointment

Question 6

Large proportion of solids, allows for breathability of the skin.

Answer 6

Paste

Question 7

Protects the skin from irritation and friction, drying effect and impart a cooling sensation via absorbing secretions.

Answer 7

Powder

Question 8

Steroid potency: increased with _______ chemical structure

Answer 8

fluorinated

Question 9

Steroid potency with class 7 being the least potent which is ________ drug

Answer 9

hydrocortisone

Question 10

1 FTU will use ______ gram cream/ointment

Answer 10

0.5 gram

Question 11

Local side effects of corticosteroids

Answer 11

Skin thinning, stretch tracks, perioral dermatitis, enlarged blood vessels, disguising infection, and susceptibility to skin infections.