week 2 Flashcards

1
Q

epigenesis

A
  • the emergence of new structures and functions in the course of development
  • the study of heritable changes in gene expression caused by interactions in our environment
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2
Q

reproduction
meiosis

A
  • cell division, eggs and sperm receive only one member from each of the 23 chromosome pairs
  • produces gametes
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3
Q

gametes

A
  • reproductive cells (egg and sperm) that contain only half the genetic material of all the cells in the body
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4
Q

process of reproduction

A
  • egg launches from one of the woman’s ovaries into the fallopian tube
  • as the egg moves through the tube towards the uterus, it emits a chemical substance that attracts the sperm towards it
  • if sexual intercourse happens near the time the egg is released conception is possible
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5
Q

sperm

A
  • 500 million released each ejaculation
  • 23 chromosomes, tail to propel
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6
Q

conception

A
  • union of an egg and sperm
  • sperm must travel for 6 hours through the uterus to the fallopian tube where the egg is
  • as soon as one sperm’s head penetrates the outer membrane of the egg, a chemical reaction seals the membrane preventing other sperm from entering
  • the tail falls off and the contents of the sperm get released into the egg
  • the nuclei of the 2 cells merge within hours
  • the fertilized egg (zygote) now has full genetic material 23 chromosomes from each sex cell
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7
Q

embryo

A
  • developing organism from week 3-8 of prenatal development
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8
Q

fetus

A
  • developing organism from the week 9- birth
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9
Q

mitosis

A
  • cell division that results in 2 identical cells
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10
Q

embryonic stem cells

A
  • cells which can develop into any type of body cell
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11
Q

androgens

A

androgens ( hormones includes testosterone): male genetalia
no androgens: (female genetalia

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12
Q

glucocorticoids

A
  • limit fetal growth
  • help fetal tissues mature
  • towards the end of gestation, glucocorticoid production increases for key organ maturation
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13
Q

identical twins (monozygotic)

A
  • twins that result from a zygote splitting in half, resulting in each of the 2 zygotes having the exact same set of genes
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14
Q

fraternal twins (dizygotic)

A
  • twins that result from 2 eggs released into the fallopian tube at the same time and are fertilized by 2 different sperm
  • only half their genes in common
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15
Q

inner cell mass layers
top

A
  • nervous system, nails, teeth, inner ear, eye lens, outer surface of skin, other internal organs
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16
Q

inner cell mass layers
middle

A
  • muscles, bones, circulatory system, inner layers of skin, other internal organs
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17
Q

inner cell mass layers
bottom

A
  • digestive system, lungs, urinary tract, glans
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18
Q

neural tube

A
  • groove formed in the top layer of differentiated cells in the embryo that eventually becomes the brain and spinal cord
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18
Q

placenta

A
  • develops along with the embryo
  • network of blood vessels, extends into the tissues of the uterus
  • 90% of the cells in the placenta come from the fetus itself
  • support organ for the fetus
  • semi permeable, exchanges some material from the mother and baby
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18
Q

amniotic sac

A
  • develops along with the embryo
  • membrane filled with a clear watery fluid in which the fetus floats
  • protective buffer for the developing fetus, temperature, cushion
  • connected to the placenta via the umbilical cord
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18
Q

umbilical cord

A
  • tube of blood vessles connecting the fetus and the placenta
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18
Q

trimester 1
week and milestone
1

A
  • zygote travels from fallopian tube to womb and embeds in uterine lining
  • cells arrange into a ball, begin to form embryo and support system
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18
Q

cephalocaudal development

A
  • areas nearer the head develop earlier than those farther away
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18
Q

trimester 1
week and milestone
2-3

A
  • embryo forms 3 layers, which will become the nervous, circulatory and digestive system
  • neural tube also develops
18
Q

trimester 1
week and milestone
4

A
  • neural tube continues to develop into the brain and spinal cord
  • primitive heart, arm and leg buds are visible
19
Q

trimester 1
week and milestone
5- 9

A
  • facial features differentiate, rapid brain growth occurs
  • internal organs form
  • fingers and toes emerge
  • start of sexual differentiation
20
Q

trimester 1
week and milestone
10-12

A
  • heart develops basic adult structures
  • spine and ribs develop more fully
  • brain forms major divisions
21
Q

trimester 2
week and milestone
13-24

A
  • lower body growth accelerates
  • fully developed external genitalia
  • body develops hairy outer covering
  • fetus can make basic facial expressions
  • fetal movements felt by mother
22
Q

trimester 3
week and milestone
25 - 38

A
  • fetus triples in size
  • brain and lungs sufficiently developed at 28 weeks, survival outside of womb
  • functional visual and auditory systems
  • fetus capable of learning
23
Q

movement

A
  • 5-6 weeks after conception fetus moves spontaneously
  • hiccups, burping reflex prepare for nursing
  • swallowing, amnionic sac fluid, develop palate and digestive system
  • “fetal breathing” moving chest wall in and out
24
Q

phylogenetic continuity

A
  • humans share many characteristics and developmental processes with non human animals due to our shared evolutionary history
25
Q

habituation

A
  • a decrease in response to repeated or continued stimulation
  • only able to become boring if it was remembered
26
Q

dishabitation

A
  • perceptible change in stimulus occurs making it become interesting again
27
Q

hazards to prenatal development
miscarriage

A
  • most common
  • 6 - 15% clinically recognized pregnancies
  • 25 - 50% of women
28
Q

teratogens

A
  • an external agent that can cause damage or death during prenatal development
  • often occur in combination, poor nutrition, exposure to pollution, stress etc
29
Q

sensitive period

A
  • period of time during which a developing organism is most sensitive to the effects of external factors
30
Q

thalidomide

A
  • morning sickness drug
    if taken when libs where growing between the 4th and 6th week after conception
31
Q

dose response relation

A
  • the greater the fetus’s exposure to a potential teratogen, the more likely it is that the fetus will suffer damage and the more sever the damage is likely to be
  • effect of exposure to an element increases with the extent of exposure
32
Q

Neonatal abstinence syndrome (NAS)

A
  • fetus’s exposed to opioids in the womb are born
  • low birth weight
  • problems with breathing/feeding
  • seizure
33
Q

teratogens
cigarettes

A
  • mother and fetus get less oxygen
  • slowed fetal growth
  • low birth weight
  • increased risk of sudden infant death syndrome (SIDS)
  • lower IQ, hearing deficits, ADHD, cancer
  • dose-response relationship
  • greatest effects earlier in gestation
34
Q

teratogens
alcohol

A
  • leading cause of fetal brain injury
  • 1/10 use alcohol during pregnancy
  • alcohol goes directly into the fetus’s bloodstream and amniotic fluid
  • fetus has less ability to metabolize alcohol
  • can result in fetal alcohol spectrum disorder (FASD) or fetal alcohol syndrome (FAS)
  • intellectual disability, attention problems, hyperactivity
35
Q

teratogen
environmental pollutants

A
  • disproportionately affects low income populations
  • diets high in fish, lead,mercury, attention, cognition
  • air pollution, low birth weight, neurotoxicity
36
Q

risks to developing fetus
age

A
  • infants born to girls 15 or younger are 3-4x more likely yo die before their first birthfay than those born to mothers who are aged between 23 and 29
  • dose response with increasing maternal age, autism
37
Q

risks to developing fetus
nutrition

A
  • need to eat a balanced diet
  • malnutrition can result in birth defects
38
Q

risks to developing fetus
disease

A
  • contracting rubella early on, devastating developmental effects
  • CMV, type of herpes, serious defects
  • zika, microcephaly
39
Q

risks to developing fetus
maternal emotional state

A
  • maternal prenatal depression, changes in brain structure in children aged 2-5, anxiety
  • increased stress if lower socioeconomic group, developing country, food insecurity
40
Q

birth experience

A
  • approx 38 weeks after conception
  • fetus rotated to the head down position
  • uterine contractions
  • squeezing stimulates hormone production, amniotic fluid out of lungs
  • survival and health of mother and baby, social integration of new person
41
Q

c sections

A
  • 28% in canada
  • assist infants and mothers facing birth complications
  • scheduling conflicts
  • maternal obesity
42
Q

state

A
  • level of arousal and engagement in the environment
  • ranging from deep sleep to intense activity
43
Q

sleep

A
  • average newborn sleeps twice as much as young adults
  • rapid eye movement sleep (REM) 50%, helps visual system
  • learn during sleep, not disconnected from external stimulation
44
Q

crying

A
  • crying because of: illness, hunger, pain, lack of control
45
Q

soothing

A
  • swaddling, wrapping in a tight blanket restricting limb movement, tactile stimulation and warmth
46
Q

colic

A
  • excessive, inconsolable crying for no apparent reason
  • could include allergies, formula intolerance, immature gut development, excessive gassiness
  • 18% of young infants
47
Q

apgar score

A
  • method for evaluating the health of the newborn immediately following birth
  • based on skin tone, pulse rate, facial response, arm and leg activity, breathing
48
Q

infant mortality

A
  • death during the first year after birth
  • rare
  • different countries criteria for determining a live birth
49
Q

low birth weight (LBW)

A
  • less than 2500g
  • can be caused by teratogens
  • higher incidence of developmental problems
  • majority are in the normal range for their development
50
Q

premature

A
  • any child born 37 weeks after conception or earlier
51
Q

small for gestational age

A
  • babies who weigh substantially less than normal for their gestational age
52
Q

developmental resilience

A
  • successful development in spite of multiple and seemingly overwhelming developmental hazards