Week 2 Flashcards
Define mood and affect
Mood = subjective feeling of sustained emotion (happy, sad)
Affect = objective immediate conveyance of emotion (blunt, flat, labile)
What is the neurochemical theory of depressions cause?
Thought to be due to low serotonin, noradrenaline, and dopamine
What is kindling theory in depression?
One episode of depression primes the brain for more with less stressful triggers
What are the main clinical features of depression?
- decreased mood
- anhedonia
Everyday for more than 2 weeks
What are the biological symptoms of depression?
- Fatigue
- sleep disturbance
- loss of appetite
- weight loss
- lowered libido
What are the cognitive symptoms of depression?
- lowered concentration
- negative thoughts
- guilt
- hopelessness
What are the psychotic symptoms of depression?
- delusions
- cotards syndrome
- hallucinations
What is agitated depression?
Usual depressive symptoms but highly restless, often agitated, pacing, psychotic
What is catatonic depression?
Severe depression leading to a state of stupor and inhibited motor activity.
Often life threatening as patients stop eating/drinking
What domains are assessed in the mental state exam?
- Appearance
- Behaviour
- Eye contact
- Speech
- Mood
- Thoughts
- Condition
- Insight
What is the HADS scale
Hospital Anxiety and Depression Scale
What are some organic causes of depression?
- Hypothyroidism
- Hyperglycaemia
- B12 deficiency
- Bushings syndrome
What is atypical depression?
Low mood like depression, but other symptoms are reversed. E.g. hypersonic instead of insomnia, increased appetite instead of decreased appetite
What are the 1st, 2nd, and 3rd line antidepressants?
1st = SSRIs
2nd = SNRIs
3rd = combination
What is the neuroanatomical aetiology of stress?
Chronic stress => neuronal change
This leads to decreased hippocampal volume
