Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ISOM > Week 2 > Flashcards

Week 2 Flashcards

1
Q

Vmax depends on [?]

A

[E]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Km?

A

Km = [S] that gives 1/2Vmax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Km is ___ related to binding affinity.

A

inversely

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Kcat (is or isn’t) dependent on the [E].

A

isn’t

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PCR can detect mutations such as:

A

small insertions (incl. trinucleotide repeat expansions), deletions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

This method can detect point mutations that remove or create a restriction site

A

PCR-RFLP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ARMS-PCR can ONLY detect

A

point mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ASO can detect

A

small insertions, small deletions, point mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

This method can detect insertions, deletions and point mutations that remove or create a restriction site, trinucleotide repeat expansions

A

Southern Blotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

This method is frequently used in identifying triplet repeat expansions

A

Southern Blotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sanger sequencing can detect

A

deletions, insertions, duplications, and point mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

This is the only method that can pick up on ALL mutations in a given region

A

sanger; good for discovering novel mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Define caudal

A

of, at or near the tail or hind parts, posterior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Define Cephalad

A

towards the head or the anterior part

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

-tomy

A

cutting into or incision (arthrotomy - cut into a joint)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

-stomy

A

surgically created opening (colostomy)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

-plasty

A

surgical repair (arthroplasty - surgical reconstruction or repair of a join)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

-algia

A

pain (metatarsalgia - pain under the metatarsal heads)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

-osis

A

abnormal condition (dermatosis - abnormal condition of the skin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

-malacia

A

abnormal softening (cardiomalacia - softening of the heart tissue)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

-megaly

A

enlargement (oranomegaly - enlargement of the organs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

sagittal plane

A

left and right (think of side view, both side and sagittal start with “S”)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

transverse plane

A

top and bottom portions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

movement occurring at a point in time

A

-tion (pronation), -xion (dorsiflexion), -sion (inversion), -ing (inverting)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

position of a structure

A

-ed (flexed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

fixed in a particular position

A

-us

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

translation movement

A

movement from one position to another in the transverse plane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

opposition

A

bringing two objects together (bringing the thumb and index finger together)

27
Q

supination (in the foot)

A

plantarflexion, adduction, inversion (ballerina touching the SoUP with her big toe)

28
Q

pronation (in the foot)

A

dorsiflexion, abduction, eversion

29
Q

How many movements in pivot joint?

A

uniaxial

30
Q

How many movements in ball and socket joint?

A

multiaxial

31
Q

How many movements in condyloid joint?

A

biaxial

32
Q

What is an example of condyloid joint?

A

knuckles

33
Q

How many movements in saddle joint?

A

biaxial (thumb)

34
Q

How many movements in hinge joint?

A

uniaxial

35
Q

How many movements in plane joint?

A

uniaxial

36
Q

This muscle shape is feather-like.

A

pennate

37
Q

This muscle shape is spindle shaped

A

fusiform (biceps brachii m.)

38
Q

Leg muscles anterior group

A

Tibialis anterior, Extensor hallucis longus, Extensor digitorum longus, Peroneus tertius
Three Eyes Examine Points (TEEP)

39
Q

Leg posterior superficial muscles

A

Gastrocnemius, soleus

40
Q

Leg posterior deep muscles

A

Tibialis posterior, Flexor digitorum longus, flexor hallucis longus

41
Q

Lateral muscle group of leg

A

Peroneus brevis (PB), Peroneus longus (PL)

42
Q

First plantar layer of the foot

A

Abductor hallucis, Flexor digitorum brevis, abductor digiti minimi

43
Q

Second plantar layer of the foot

A

Quadratus plantae, Lumbricals (there are 4)

44
Q

Third plantar layer of the foot

A

Flexor hallucis brevis, Adductor hallucis, Flexor digiti minimi brevis

45
Q

Fourth plantar layer of the foot

A

Plantar Interossei (there are 3)

46
Q

Macule

A

a flat lesion represented only by a color change on the skin (you cannot feel the border with your finger)

47
Q

Papule

A

a solid raised lesion with distinct borders

48
Q

Plaque

A

a solid, raised, flat-topped lesion

49
Q

Vesicle

A

a raised lesion (often filled with clear fluid) <1cm

50
Q

Bullae

A

circumscribed (outline is obvious) fluid-filled lesion >1 cm

51
Q

Pustule

A

circumscribed, elevated pus filled

52
Q

Wheal

A

edema or swelling

53
Q

Burrow

A

linear lesion that is produced by infestation of skin

54
Q

Telangiectasia

A

spider vein

55
Q

Excoriation

A

broken area of skin due to scratching

56
Q

Lichenification

A

thickening of the epidermis

57
Q

Eschar

A

hard plaque covering an ulcer or wound (may look like charcoal)

58
Q

Petechiae

A

small, bleeding lesions that do not blanch with pressure

59
Q

Purpura

A

large hemorrhagic areas of bleed

60
Q

primary radiation

A

the radiation emitted from the X-ray tube

61
Q

Scatter radiation

A

radiation that enters a patient and is deflected from its initial course but may still contact and expose the x-ray film

62
Q

What are the 3 basic amino acids?

A

Lysine (Lys, K), Histidine (His, H), Arginine (Arg, R)

63
Q

A nucleosome contains

A

core octamer subunit, histones (H1, H2A, H2B, H3, H4), basic/positive charged amino acid residues (K, H, R)

64
Q

Adding an acetyl group (acetylation) to a histone will

A

weaken the DNA-Histone interaction. the acetyl group will neutralize the positive charge of the lysine making the bond to negatively charged DNA weaker

65
Q

Cytosine methylation

A

adding a methyl group to cytosine which is a permanent process. this silences the gene

66
Q

Which subunit of eukaryotic DNA polymerase is the activity hub (has primase activity)

A

alpha

67
Q

Which subunit of eukaryotic DNA polymerase is the proofreader?

A

delta

ISOM (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions