Week 2 Flashcards
Blood brain barrier
A physiological mechanism that alters the permeability of brain capillaries, so that some substances, such as certain drugs, are prevented from entering brain tissue, while other substances are allowed to enter freely.
Diagnosis of Substance Use Disorder (SUD)
User has significant and recurring impairments in their life as a result of the drug(s).
Tolerance
Reduction in the effect of a drug as a result of repeated use, requiring users to consume greater quantities to achieve the same effect.
-Often the result of the bodies attempt to maintain homeostasis
Heroine consumption
Hypoventalation caused by heroine causes the body to increase breathing
Withdrawal
Unpleasant effects of reducing or stopping consumption of a drug that users had consumed habitually.
Depressants
Drugs that create a decrease in nervous system activity.
Alcohol
- Increases GABA
- Decreases Glutamate
- At low doses inhibitory control centers in the cortex are “depressed”.
- Creates a release of inhibitions
-“Upper” phase of drinking.
What does alcohol/depressants do at higher doses
- Loss of motor coordination
- Impaired judgment
- “Downer” phase of drinking.
What is alcohol myopia
A “short-sightedness” in thinking caused by a inability to pay attention to as much information as a sober person.
Barbiturates and Tranquilizers
- a.k.a. sleeping pills and sedatives
- Increase GABA activity.
- Very addictive
- At high doses can lead to depression, a loss of motor coordination, and memory impairments.
Stimulants
Drugs that create an increase in nervous system activity.
Amphetamines
- Reduce sleep, fatigue, appetite, and depression.
- Increase dopamine and norepinephrine.
- Injections can lead to massive spikes in blood pressure causing a stroke.
Amphetamine Psychosis
Schizophrenia-like hallucinations that occur when the brain’s dopamine activity is artificially increased far beyond normal levels by heavy and/or continuous amphetamine use.
Methamphetamine
- Inhaled via smoking
- Ingredients to produce it are very accessible.
- More potent than standard amphetamines.
-Increased probability of OD and dependence. - Can cause aggression, paranoia, acne, “meth mouth”
MDMA (ecstasy)
3,4-Methylenedioxymethamphetamine