Week 2 Flashcards
8-10% of 5-7 yo have ____ when diagnosed with ___
sinusitis, URI
Which is more common, more severe: Viral or Bacterial sinusitis?
Viral - more common
Bacterial - more severe
What are the three types of rhinosinusitis?
Viral, Bacterial, Fungal
What are predisposing factors for rhinosinusitis?
decongestants, fatigue, dental problems, food sensitivities, GI issues, septal deviation, large adeonoids, foreign bodies
What are the distinguishing features between acute and chronic rhinosinusitis?
duration of symptoms (3 wks is cut-off), aggressive symptoms (fever, facial pain) not as apparent in chronic cases
What is purulent discharge?
discharge filled with pus, yellowish color
What are the two most important complications possible with rhinosinusitis?
orbital/periorbital cellulitis, cavernous sinus thrombosis
What are symptoms of cavernous sinus thrombosis?
high fever, chills, prostrated, comatose, change in mental status
What are the early signs of cavernous sinus thrombosis?
deep eye pain, ocular palsy (III, IV, VI), diplopia
What are the late signs of cavernous sinus thrombosis?
both eyes involved, edema, death within 2-3 days
What is a common, non-dangerous sequellae to rhinosinusitis?
Upper Airway Cough Syndrome (UACS, post-nasal drip)
What might you find on a PE for UACS?
tonsilloliths, cobblestoning of oropharyngeal mucosa, tenderness of sinuses
What symptoms are never seen in patient with allergic?
fever, ms pain
What symptom is common to URI, allergy, and influenza?
nasal discharge
What condition is commonly found underneath the tongue?
squamous cell carcinoma
What condition is commonly found at the back/root of the tongue?
tongue cancer
Important things to ask for history for oral cavity/throat/neck
date of last dental exam, diet, hygiene habits, history of smoking/alcohol/drug use, history of x-ray of head/neck
What does the oral exam entail?
inspection (tongue blade + light source), palpation if indicated (gloves)
What condition can fetor oris be associated with?
appendicitis
What symptom is very common in URIs?
sore throat
Fever: URI, allergy, influenza
URI: low grade possible, allergy: never, influenza: very common (100-102)
Headache is rare for (URI, allergy, influenza)?
URI
Headache: URI, allergy, influenza
URI: rare, allergy: uncommon, influenza: common
Cough: URI, allergy, influenza
URI: common, allergy: sometimes, influenza: common dry cough
MS Pain: URI, allergy, influenza
URI: slight, allergy: never, influenza: very common
Malaise: URI, allergy, influenza
URI: sometimes, allergy: sometimes, influenza: very common
Sore Throat: URI, allergy, influenza
URI: very common, allergy: sometimes, influenza: sometimes
Sneezing: URI, allergy, influenza
URI: common, allergy: common, influenza: sometimes
Lacrimation: URI, allergy, influenza
URI: rare (conjunctivitis), allergy: common, influenza: soreness behind eyes
Is lacrimation common in URI?
rare, conjunctivitis
Sweet breath can be indicative of ___.
diabetic ketoacidosis
Faintly sulfurous breath can be indicative of ____.
liver failure
Ammonia breath can be indicative of ____.
renal failure
What are possible causes of xerostomia?
mouth breathing, dehydration, diuretics, salivary disease, sialoliths, sjogren’s syndrome
Deviation of uvula is always indicative of cranial nerve dysfunction (T/F)
False, uvula deviation can be normal. Focus on symmetrical elevation of soft palate.
Abnormal deviation is related to cranial nerve ___.
XII (hypoglossal nerve)
What does a CBC tell us?
count/quality of WBC, count/quality of RBC
What are symptoms of B12 deficiency seen in the tongue?
beefy red, enlarged, soreness
Classic presentation of recurrent herpes labialis?
prodromal sensations where lesion previously appeared, painful vesicle appears and erupts, ulcer remains, crusts over, heals
Characteristics of recurrent herpes labialis?
viral infection, high incidence, contagious, episodes of painful blisters on the lip
Type of herpes most commonly linked to herpes of the mouth?
HSV-1
Reactivation triggers: recurrent herpes labialis
UV light, fatigue, trauma, stress, menstruation
When should you be concerned with autoinnoculation (w/ herpes)?
when it spreads the eyes
Prodromal symptoms: herpes
itching, burning, tingling lasting approximately 12-36 hours
Etiology: Carcinoma of the lips
tobacco, alcohol, sunlight, poor oral hygiene, poorly fitting dentures
Characteristics of the lesions present with SCC?
painless, well-demarcated, elevated, indurated border with ulcerated base, verrucous/plaque-like
Prognosis: carcinoma of the lips
slow-growing, poor healing, bleeding probable, high risk of metastasis
Morphology: mucocele
soft cyst, mucin-fileld cavity, can appear red/purple, movable
Location: mucoceles
lips, under tongue
What is another name for mucoceles?
ranula
In what patient population are mucoceles most common?
< 20 years
Etiology: Chelitis
use of retinoids, wind-burn, allergies
What is chelitis?
erythema and scaling of the lips
What is angular chelitis?
inflammatory lesion at the labial commissure, often bilateral
What is an inflammatory lesion at the labial commissure that is often bilateral?
angular chelitis
What are the signs and symptoms of angular chelitis?
deep cracks, bleeding/splitting if severe, shallow ulcers
Angular chelitis lesion can become infected by ___
candida albicans, staph aureus
What are some conditions where secondary lesions can appear?
measles, scarlet fever, pellagra, scurvy, erythema multiforme, syphilis, uremia
Pellagra is a deficiency of ____
vitamin B3
A smooth fiery tongue and painful mouth can be symptoms of ____.
Pellagra
What conditions can present with painless lesions?
oral lichen planus, syphilis, mucocele, scc
Morphology: oral lichen planus
lace-white patches/papules/streaks on the buccal mucosa (Wickham striae), erosions on the gingival margin
Is oral lichen planus contagious?
No
Morphology: leukoplakia
white patches/plaque on oral mucosa, cannot be rubbed off; patches can be darker esp with heavy tobacco use; vary in thickness
What is a key difference between leukoplakia and candida?
candida can be rubbed off, leukoplakia cannot
Etiology: leukoplakia
AIDS, tobacco use, oral sepsis, alcoholism, vitamin deficiency, syphilis, dental galvanism, actinic radiation (w/ lip involvement), trauma, endocrine disturbance
Leukoplakia always signifies a malignancy (T/F).
false, leukoplakia is also seen in inflammatory conditions; only 20% of lesions progress to cancer in 10 years
Sex/Age: leukoplakia
M > F, ~90% > 40 yo
What PE should be done if leukoplakia is suspected?
lesion cannot be wiped away with gauze, cervical lymphadenopathy
What are concerning signs when palpating lymph nodes?
hard, immovable, painless, large/getting larger
Where are the most common locations for finding leukoplakia?
tongue, mandibular alveolar ridge, buccal mucosa in > 50% of cases
DDx: leukoplakia
candidiasis, aspirin burn, erythroplakia, dysplastic lesion
Morphology: erythroplakia
red macule, well-demarcated, soft texture
Common location: erythroplakia
floor of mouth, tongue, palate
What are risk factors for erythroplakia?
smoking, alcohol
What are risk factors for Oral SCC?
smoking (90% of pts w/ SCC), alcohol
Common locations (3): Oral SCC
Floor of mouth, lateral/ventral surface of tongue (40%), lower lip (38%), palate/tonsillar area (11%)
Is Oral SCC always painless?
No, ulcerated lesions can be painful
What can be the first symptom of oral SCC?
metastatic mass (non-tender) in the neck
Morphology: oral SCC
may appear as erythroplakia/leukoplakia, exophytic or ulcerated, rolled border
Morphology: melanoma
pigmented lesions, asymmetric, irregular borders, variable coloration, increasing diameter, doesn’t blanch
DDx: melanoma
melanosis (symmetric lesions in individuals with dark skin), oral melanotic macules (symmetric, stable, sharply delimited dark macules on lips/oral mucosa)
Morphology: Fordyce’s spots
multiple, white-to-yellow, 1-2 mm papules, often in a cluster opposite molars
Location: Fordyce’s spots
vermillion/buccal mucosal border, inner surface of lips, retromolar region, tongue, gingiva, frenulum linguae, palate
What are Fordyce’s spots?
asymptomatic, benign neoplasms from sebaceous glands
Sex/Age: Fordyce’s spots
M = F, 20-30 years
DDx: Fordyce’s spots
candida albicans (Fordyce’s spots do not rub off)
What is stomatitis?
inflammation of oral tissue from local/systemic disease that may be accompanied by foul breath/mucosal bleeding
Risk factors: oral candidiasis
dentures, diabetes, antibiotics, chemotherapy/radiation, HIV/AIDS, inhaled glucocorticoids
Oral candidiasis is common in ____
infants
Diagnosis of oral candidiasis can be confirmed with ____
KOH prep
Morphology: oral candidiasis
lesion, slightly raised, white plaques, hyperemic, soft-looking, easily wiped away, mouth appears dry
What is recurrent aphthous stomatitis?
“canker sores”, acute, painful, recurring, solitary/multiple necrotizing ulcerations of the oral mucosa
What is the most common trigger of recurrent aphthous stomatitis?
trauma
What are two conditions with similar prodromal symptoms (burning/tingling)?
herpes and canker sores
DDx: recurrent aphthous stomatitis
secondary herpetic ulceration, Crohn’s, neutropenia, sprue, trauma, pemphigus vulgaris, cicatricial pemphigoid
What is the medical term for cold sores and what is their main cause?
herpetic gingivostomatitis, HSV-1
What is a macule?
lesion within the dermis, < 1 cm
What is a patch?
lesion within the dermins, > 1 cm
What is a papule?
raised, solid lesion < 1 cm
What is a plaque?
raised, solid lesion > 1 cm
What is a vesicle?
superficial, palpable lesion filled with fluid, < 1 cm
What is a bulla(e)?
superficial, palpable lesion filled with fluid, > 1 cm
What are different ways to classify mouth lesions?
painful/painless, type of lesion, coloration, size, benign/cancerous/precancerous
What is the classic sign of erythema multiforme?
target lesions on the skin
Morphology: aphthous stomatitis
shallow, round/oval lesions with grayish base and red border
What is the classic sign of erythema multiforme?
target lesions on the skin
Sx: aphthous stomatitis
painful lesions, occasionally have prodromal burning/tingling
abbreviation: NT
non-tender
abbreviation: TTP
tender to palpation
Location: aphthous stomatitis
non-keratinized, moveable mucosa (buccal/labial mucosa, buccal/lingual sulci, ventral tongue, soft palate, floor of mouth)
DDx: aphthous stomatitis
secondary herpetic ulceration, pemphigus vulgaris, cicatricial pemphigoid, Crohn’s dz, neutropenia, sprue
Sx: herpetic gingivostomatitis
prodromal pain/burning/tingling, painful eruption of unmovable oral mucosa and vermilion border, fever, malaise, LA, painful eating
DDx: herpetic gingivostomatitis
aphthous stomatitis, erythema multiforme, drug eruptions, pemphigus
Prognosis: herpetic gingivostomatitis
self-limited to 1-2 weeks, recurrent infxs as virus goes into latency
Sx (kids): herpetic gingivostomatitis
fever, LA, drooling, pain, dehydration due to decreased oral intake
Labs: herpetic gingivostomatitis
Tzanck smear, direct immunofluorescence smear, viral culture
Differences (symptoms): aphthous stomatitis and herpetic gingivostomatitis
In addition to painful lesions, herpes lesions can also have accompanying symptoms (fever, malaise, LA)
Differences (location): aphthous stomatitis and herpetic gingivostomatitis
herpes lesions can appear on the vermilion border and unmovable mucosa, while canker sores will always appear inside the oral cavity (unmovable and movable mucosa)
Differences (morphology): aphthous stomatitis and herpetic gingivostomatitis
herpes lesions will often have crusting
DDx: oral erythema multiforme
aphthous stomatitis, allergic stomatitis, pemphigus, herpes
Similarities: aphthous stomatitis and herpetic gingivostomatitis
painful/recurrent lesions, prodromal sxs (burning/tingling), common triggers (stress/fatigue), often self-limited