Week 13 - Neuro-Endocrine System Flashcards

1
Q
Neuroendocrine system  (2)
Nervous system uses
Endocrine system releases
A
  • Uses neurotransmitters

- Releases hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Endocrine glands release

A

Release hormones directly into the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hormone purpose

A

Alter the activity of tissues that possess receptors to which the hormone can bind

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hormone definition

A

Chemical messengers from endocrine glands that travel in the blood placing them in direct contact with all cells.
-Can travel in the blood to their specific target organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Receptor are ____ to hormones

A

specific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Each cell has ____ to _____ specific receptors

A

2000, 10,000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The ____ plasma hormone concentration determines the magnitude of the effect at the _____ level

A

free

tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Blood hormone concentration determined by rate of: (2)

A
  • Secretion of hormone from endocrine gland

- Metabolism or excretion of hormone (at the receptor and by the liver and kidneys)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Blood hormone concentration determined by quality of____ _____(____ _____)

A

Transport protein (steroid hormone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Blood hormone concentration determined by changes in ____ ____

A

plasma volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hormones affect only tissue with ____ _____

A

Specific receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Magnitude of Hormone-Receptor interaction depends on: (3)

A
  • concentration of the hormone
  • number of receptors on the cell
  • affinity of the receptor for the hormone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Downregulation

A

Decrease in receptor number; in response to high concentration of hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Upregulation

A

Increase in receptor number in response to low concentration of hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mechanisms of hormone action (3)

A
  • Altering membrane transport (insulin)
  • Stimulate DNA to increase protein synthesis (steroid hormone)
  • Activating second messengers via G-protein (cyclic AMP)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Steroid Hormone characteristics (4)

A
  • Lipid soluble
  • Diffuses easily through cell membranes; receptor located within cell
  • Chemical structure is derived from or is similar to cholesterol
  • Secreted by adrenal cortex (e.g. cortisol), ovaries (e.g. oestrogen), testes (e.g. testosterone)
17
Q

Non steroid hormone characteristics (3)

A
  • Nonlipid soluble
  • Cannot easily diffuse through cell membranes; receptors located on cell membranes
  • Two types: amino acid derivatives (e.g. epinephrine) and protein or peptide hormones (e.g. insulin)
18
Q

Anterior Pituitary gland hormones (3)

A
Adrenocorticotropic hormone (ACTH)
Thyroid-stimulating hormone (TSH)
Growth hormone (GH)
19
Q

Posterior pituitary gland

A

Antidiuretic hormone (ADH)

20
Q

Growth hormone Purpose

A

Stimulate release of insulin-like growth factors

21
Q

Growth hormone essential growth of ____tissues
e.g.___ ___ uptake and _____ synthesis.
____ bone growth

A

All
amino acid, protein
Long

22
Q

Growth hormone reduces the use of ____.
Increases________
Mobilizes____ ____ from _____ tissue

A

plasma glucose
gluconeogenesis
fatty acids from adipose tissue

23
Q

Anti Diuretic hormone stimulated by

A

High plasma osmolality and low plasma volume (due to sweat loss without water replacement)

24
Q

Anti diuretic hormone reduces

A

water loss from the body to maintain plasma volume (favours reabsorption of water from the kidney)

25
Thyroid gland hormones (2)
Triiodothyonine (T3) | Thyroxine (T4)
26
T3 and T4 purpose (2)
maintenace of metabolic rate | allowing the full effect of other hormones
27
Adrenal Medulla hormones Name of Hormones receptor Effects depend on
Epinephrine, noepinephrine bind to adrenergic receptors (alpha, beta) Hormone used and receptor type
28
Adrenal cortex hormones | purpose of hormone (2)
Aldosterone (mineralcorticoid) controls Na+ reabsorption and K+ secretion regulation of blood volume and blood pressure
29
Aldosterone stimulated by (2)
increased K+ concentration | decreased plasma volume
30
Adrenal gland hormone | purpose (4)
Cortisol (glucocorticoid) - Promotes protein breakdown for gluconeogenesis and tissue repair - Stimulates FFA mobilization, glucose synthesis - Blocks uptake of glucose into cells (promotes use of FFA's as fuel)
31
Cortisol stimulated by (2)
Stress, via ACTH | Exercise
32
Hormones of the pancreas (2)
Insulin from beta cells | Glucagon from alpha cells
33
Insulin purpose
promotes the storage of glucose, amino acids and fats
34
Glucagon purpose
promotes the mobilization of fatty acids and glucose
35
Testes
Testosterone (anabolic steroid) tissue building performance enhancement
36
Ovaries produce____ | Function
Estrogen - establish and maintain reproductive function - levels vary throughout the menstrual cycle
37
Blood glucose maintenance controlled by_____
hormones (corisol, growth hormone)
38
Plasma glucose maintained through 4 processes:
- Mobilization of glucose from liver glycogen stores, FFA from adipose tissue - Gluconeogenesis from amino acids, lactic acid, and glycerol - Blocking the entry of glucose into cells
39
Master gland also known as____ ____ | Its purpose
pituitary gland | regulates activity of endocrine glands