Week 13

Question 1

Which substance is the main psychoactive/addictive substance in marijuana?

Answer 1

tetrahydrocannabinol (THC)

Question 2

What are the two cannabinoid receptors and which one is involved in marijuana’s addictive properties?

Answer 2

CB 1 and CB 2.

CB1 is involved in the addictive properties

Question 3

What are some symptoms of acute marijuana intoxication?

Answer 3

Short term memory and attention impairment

motor skills and reaction time impairment

effects decision making and executive function

Can act as either a stimulant or depressant depending on concentration of THC

Question 4

What are the symptoms of acute marijuana withdrawal??

Answer 4

Anger, irritability, aches, depression, poor concentration, sweating, craving, insomnia

Question 5

Why is withdrawal with marijuana slower than other substances?

Answer 5

slow release from THC stored in adipose tissue (Fat)

Question 6

What is the system of the brain related with marijuana use?

Answer 6

Endogenous Cannabinoid System

Question 7

What is the naturally occurring neurotransmitter for the Endogenous Cannabinoid System?

Answer 7

Anandamide

Question 8

Why is marijuana so popular among adolescents?

Answer 8

inverse relationship between perceived risk and drug use (the less they think a drug poses a risk, the more likely they are to use)

Question 9

What are some of the risks of chronic marijuana use?

Answer 9

decreased motor function, psychosis, lower IQ, short term memory loss

Question 10

What substance is very potent, has unreliable effects, and can have serious side-effects?

Answer 10

Synthetic cannabinoids (Spice, K2)

Question 11

How many states is marijuana legal?

Answer 11

15

Question 12

What schedule is marijuana and is it legal for Docs to prescribe?

Answer 12

schedule 1 and no.

Question 13

What is the leading cause of preventable death?

Answer 13

tobacco

Question 14

What is the primary psychoactive/addictive substance in tobacco?

Answer 14

nicotine

Question 15

What receptor does nicotine bind to?

Answer 15

acetylcholine receptor

Question 16

Even though nicotine binds to the acetylcholine receptor, what is the primary action that makes nicotine addictive?

Answer 16

the release of dopamine

Question 17

The removal of an aversive (unpleasant) stimulus which reinforces/increases a certain behavior or response?

Answer 17

Negative Reinforcement

Question 18

How are cigs a good example of negative reinforcement?

Answer 18

The chronic nicotine user experiences withdrawal every morning. When the individual ingests nicotine, it attaches to receptors releasing acetylcholine, dopamine, etc., which alleviates the withdrawal symptoms

Question 19

The initial use of nicotine will be pleasurable and produce a mild high. This is an example of what kind of reinforcement ?

Answer 19

positive

Question 20

What is a major risk factor in developing a tobacco use disorder?

Answer 20

age of first use

Question 21

What are symptoms of nicotine intoxication?

Answer 21

release of dopamine makes the smoker feel more calm, relaxed, satisfied, mild euphoria.

Question 22

What are the symptoms of nicotine withdrawal?

Answer 22

Irritability, depression and anxiety

Question 23

How much are your chances of recovery increased if you quit smoking?

Answer 23

2x

Question 24

T or F - smoking cessation has immediate and significant health benefits?

Answer 24

True

Question 25

What are some smoking cessation options?

Answer 25

Behavioral treatments -counseling, therapy, group support, telephone quite lines

Medication - Nicotine replacement (patch, gum, lozenges). Bupropion (Zyban or Wellbutrin) Varenicline (Chantix)

Question 26

T or F - nicotine replacement is using nicotine agonists to treat withdrawal and cravings

Answer 26

true

Question 27

vareniciline (Chantix) is what type of drug

Answer 27

partial agonist

Question 28

What are some negative effects with Chantix?

Answer 28

it can worsen heart disease and may worsen depression and suicidal ideation in some patients