Week 11- Nervous System Flashcards
The Brain
- Communication and control centre of the body
- Receives, processes and evaluates many kinds of input, decides on the response needed, and acts on that
What is the brain controlled by?
- Involuntary activity- Autonomic Nervous System
- Voluntary- Somatic Nervous System
What is the brain protected by?
- The skull
- Meninges
- Cerebrospinal fluid
Meninges
- Consists of 3 continuous connective tissue membranes covering the brain and spinal cord
Dura Mater
- Outer layer
- Tough, fibrous double layered membrane
- Forms the dural sinuses which collect venous blood and CSF for return to the general circulation
Subdural Space- Lies beneath the dura
- Potential space
- Normally, empty but can fill with blood after an injury
Arachnoid Mater
- Middle layer
- Loose, web like covering
Subarachnoid Space
- Contains CSF and cerebral arteries and veins
- Lies below the arachnoid
Pia Mater
- Inner layer
- Delicate, connective tissue that adheres closely to all convolutions to the surface of the brain
- Contains many small blood vessels
Cerebrospinal Fluid (CSF)
- Provides a cushion for the brain and spinal cord
- Clear, almost colourless liquid
- Formed in the ventricles in the brain and flows into the subarachnoid space
- Here it circulates around the brain and spinal cord eventually returns to the venous blood
- To maintain normal pressures (ICP), it is important that equal amounts of CSF
CSF & Arachnoid Vili
- Small protrusions of the through the dura mater
- They protrude into the venous sinuses of the brain, and allow CSF to exit the subarachnoid space and enter the bloodstream
- Once in the bloodstream, it is carried away and filtered by the kidneys and liver the same way other fluids are
Blood Brain Barrier
- Protective mechanism provided by relatively impermeable capillaries in the brain
- Cells are tightly joined together rather than possessing pores
- This barrier limits the passage of potentially damaging materials into the brain and controls the delicate balance of electrolytes, glucose and proteins in the brain
- Lipid soluble substances can still pass through
Cerebral Hemispheres
- Make up the largest portion of the brain
- 2 hemispheres separated by a fissure
- Each hemisphere is divided into 4 major lobes (frontal, parietal, occipital, temporal)
- Each has specific functions
- Each hemisphere is concerned with voluntary movement and sensory function in the opposite side of the body
What are the 2 areas involved in language
- Broca’s area
- Wernicke’s area
Broca’s Area
- Motor or expressive speech area
- Controls the output of words, both verbal and written and ensures they are coordinated in an appropriate and understandable way
- Located at the base of the left frontal lobe
Wernicke’s Area
- Integration centre that comprehends language received, both written and spoken
- Located in the posterior temporal lobe
- Has connective fibres to the visual and auditory areas
Limbic System
- In cerebral hemispheres
- Not a separate system but a collection of structures
- Responsible for emotional reactions and feelings
- Has many connections to all areas of the brain
- Linked to the hypothalamus- responsible for the autonomic responses associated with emotions (altered BP, nausea, etc)
Diencephalon
- Central portion of the brain
- Contains the thalamus and hypothalamus
Thalamus
- Main nerve bodies that serve as a sorting and relay station for incoming sensory impulses
Hypothalamus
- Key role in maintaining homeostasis in the body
- Regulation of body temp, intake of food and fluid and the regulation of sleep cycles
- Regulations of libido
Brainstem
- Connects the brain to the spinal cord
- Contains: Pads, Medulla Oblongata, RAS
Pons
- Contains afferent (incoming) and efferent (outgoing) fibers
Medulla Oblongata
- Vital control centre that regulate respiratory and cardiovascular function
RAS (Reticular Activating System)
- Determines the degree or awareness of the cerebral cortex (decides which of the incoming sensory impulses the brain ignores and which it notices)
Cerebellum
- Lies dorsal to pons and medulla, below the occipital lobe
- Function to coordinate movement and maintain posture and equilibrium
- Takes impulses from visual pathways, vestibular pathways (inner ear), propioceptors in joints and muscles
Blood Supply to the Brain
- Supplied by the internal carotid arteries and vertebral arteries
- Each internal carotid is a branch of the left and right common carotid
- Vertebral arteries branch off the subclavian arteries
- Each of these artery’s branch to form smaller arteries that provide the blood supply to the entire brain
- Once deoxygenated, venous blood from the brain collects in the dural sinuses and then drains into the right and left jugular veins to be returned to the heart
Circle of Willis
- Structure located inside the head that supplies blood to the brain
- Ensures blood flow remains unimpeded in case any of the principal supplies are damaged
- This means if one of the vessels supplying blood to the brain is blocked or narrowed, the other vessels can preserve cerebral perfusion to prevent ischemia
How many cranial nerves do we have?
- 12 Pairs
Where do the cranial nerves originate from?
- Originate from the brainstem and pass into the skull to serve structures in the head and neck
- May consist of motor fibres only or sensor fibres, or a mix of both
Oh, Oh, Oh To Touch And Feel A Girls Vagina, So Hot
Olfactory
Optic
Oculomotor
Trochlear
Trigeminal
Abducens
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Spinal accessory
Hypoglossal
Olfactory
- Sensory, smell
Optic
- Sensory, vision
Oculomotor
- Motor, eye movements including eyelids
Trochlear
- Motor, eye movements
Trigeminal
- Sensory/ motor, general sensory- eye, nose, face, or oral cavity, teeth
- Speech muscles
Abducens
- Motor, eye movements
Facial
- Sensory/ motor, taste, muscles of facial expression, scalp muscles
Vestibuculocochlear
- sensory/ motor, taste, gag reflex
Vagus
- Sensory/ motor, external ear, parts of taste, heart and lungs smooth muscle, glands of GI system, diaphragm
Spinal Accessory
- Motor, voluntary muscle of pharynx, head movements
Hypoglossal
- Motor, muscles of the tongue
Spinal Cord
- Protected by the bony vertebral column, meniges and CSF
- Starts at the medulla oblongata and ends at the level of the 1st lumbar vertebrae
- Past thus, there is a bundle of nerve roots known as the Cauda Equina
- Consists of nerves that innervate the skeletal muscles
- Ascending and descending tracts
Ascending and Descending Tracts
- Ascending relay information from the skeletal muscles to the brain
- Descending from the brain to the muscles for movement
Spinal Nerves
- 31 pairs located in the spinal column
- Carry motor and sensory fibres to and from the organs and tissues
- Innervate at the skin level- called dermatomes
Reflexes
- Automatic, rapid, involuntary responses to a stimulus
- Involves a stimulus from a receptor that is conducted along an afferent nerve fibre, tells the brain, send an efferent stimulus back to the peripheral nerve to elicit a response
- Can also have acquired reflexes (salivation with smell of food)
Neurons
- Highly specialized cells that conduct impulses throughout the CNS and PNS
- Require glucose and O2 for metabolism
- Structure can vary depending on its function
- They all have: dendrite, cell body, axon, covered in myelin sheath, nodes of ranvier
Dendrite
- Receptor site, conducts the impulse towards the cell body
Cell Body
- Contains the nucleus
Axon
- Conducts impulses away from the cell body towards the effector site or connecting neuron
Covered in myelin sheath
- Insulates the fibre and speeds up the rate of conduction
Nodes of Ranvier
- Spaces between the myelin sheath
Impulse Transmission
- Impulses are transmitted from cell to cell via chemical neurotransmitters
- Involves the presynaptic and postsynaptic synapses
- Axon and receptor are separated by a synaptic cleft- filled with fluid
- In order for impulses to travel along, the released chemical flows across the cleft to the receiving receptor (Receptors are specific for each type of chemical)
What are the different types of neurotransmitters?
- Acetylcholine
- Norepi/ Epinephrine
- Dopamine
- Serotonin
Acetylcholine
- Chief neurotransmitters in the PNS
Norepi/ Epinephrine
- Neurotransmitters in the SNS
- Causes vasoconstriction and increase in HR
- Stimulates alpha and beta receptors
Dopamine
- Released when your body is expecting a reward
- Cycle of motivation, reward, reinforcement
Serotonin
- Mood, sexual desire and function, appetite, sleep, memory and learning, temperature regulation, and some social behaviour
Autonomic Nervous System
- Acts as the involuntary control
- Incorporates the SNS and PNS (typically have antagonistic effects, key in maintaining homeostasis)
- SNS & PNS
Sympathetic Nervous System
- Increases the level of activity including cardio, resp and neuro functions
- Fight or flight, stress
- Involve release of Ach, epi, and norepi
Parasympathetic Nervous System
- Dominates the digestive system and aids in the recovery after the sympathetic stimulation
- Responsible for slowing RR, HR, constriction of pupils
- Largely innervated by the vagus nerve
- Active chemical neurotransmitter is Ach as well