week 11 Flashcards

1
Q

fibroseremmers

A

pirfenidom, nintedabib, (prednison?)

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2
Q

fibrose

A

te veel collageen (type I, III)
orgaanfalen door littekenvorming

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3
Q

wondgenezing

A
  1. homeostase: trombine + fibrine, vasoconstrictie
    2: ontsteking/inflammatie: vasodilatatie, chemotaxie, cellulaire respons
    3: proliferatie: wond dicht, angiogenese, myofibroblasten contraheren en brengen wondwondjes samen
    4: herstel: ophopen fibroblasten beïndigt
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4
Q

medicatie bij wondgenezing

A
  1. homeostase: antistolling
    2: ontsteking/inflammatie: ontstekingsremmers
    3: proliferatie: proliferatieremmers
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5
Q

restrictie

A

TLC < -1,64 of 80% van voorspeld
FEV1 omlaag
FEV1/VC - of omhoog

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5
Q

obstructie

A

FEV1/FVC < 1,64 of 70% van voorspeld
FEV1 omlaag
FEV1/FVC omlaag

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6
Q

Kroghfactor formule

A

KCO= diffussiecapaciteit membraan= TLCO/Va

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7
Q

6 min wandeltest

A

afstand, saturatie, borgscore, HF, BP

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8
Q

fibrose

A

compliantie verlaagd, elastantie verhoogd

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9
Q

densiteit verhoogd

A

consolidatie, matglas

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10
Q

densiteit verlaagd

A

emfyseem, cysten

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10
Q

antracosis

A

roet in de longen

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11
Q

silicose

A

fibrose door steen/silica

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12
Q

berylliose

A

fibrose door beryllium

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13
Q

sarcoïdose

A

vaag ziektebeeld, door gehele lichaam ontstekingen

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14
Q

histologische triade van de EAA

A

cellulaire interstitïele pneumonitis
cellulaire bronchitis
granuloomvorming

15
Q

lab EAA

A

antistoffen
leuko’s hoog
lymfocyten hoog

16
Q

behandeling EAA

A

prednison, evt steroïden

17
Q

respiratoire insufficiënte type 1

A

longfalen: partieel, PaO2 omlaag

18
Q

respiratoire insufficiëntie type 2

A

vaak pompdalen: compleet, PaO2 omlaag, PaCO2 omhoog

19
Q
A