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1B3 > nieren > Flashcards

nieren Flashcards

1
Q

glomerulaire protéinurie

A

defect lading/grootte selectiviteit

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2
Q

overflow proteïnurie

A

tumorspecifieke eiwitten, Bence Jones eiwitten

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3
Q

tubulaire protéinurie

A

laagmoleculair, vooral prix tubulus

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4
Q

hoog cystatine C

A

tumor

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5
Q

IgA nefropathie

A

hematurie
met IgG kun je laten fluoriseren
IgA slaat neer als er veel van is in mesangium

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6
Q

syndroom van Alport

A

hematurie
jongetjes doof
COL4A5 zit op X-chromosoom
nierinsufficientie

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7
Q

thin membrane disease

A

hematurie
heeft alleen COL4A3 of COL4A4

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8
Q

glomerulair probleem

A

proteïnurie >3,5 gr

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9
Q

focaal segmentale glomerulosclerose

A

niet overal in de nier
fibrosering glomerulus
zwarte microscopie
COL4A mutaties

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9
Q

minimal change disease

A

albumine proteinurie
basaalmembraan verliest negatieve lading
kinderen

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10
Q

membraneuze glomerulopathie

A

immunoglobulientjes binden aan het brede deel podocyt (gericht tegen PLA2 receptor) IgG antigenen
verdikt basaalmembraan

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11
Q
A
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11
Q

proteïnurie remmen

A

bloeddruk verlagen: ACE of ARB, NSAID

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12
Q

behandeling nefrotisch syndroom

A

prednison, cyclofosfamide, azathioprine, cyclosporine, rituximab

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13
Q

nefritisch syndroom kenmerken

A

hematurie
proteïnurie (<3gr)
oedeem
hypertensie
oligurie
crescents kapsel van Bowman

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14
Q

halve maan crescents

A

1B3 (3 decks)

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