Week 10 Flashcards
pns- afferent division
conveys information from the sensors in the periphery to the cns
spinal cord
long cylinder of nerve tissue which extends down from the brainstem to the second lumbar vertebrae
pns- efferent division
somatic nervous system- nerve fibres innervate skeletal muscle
autonomic nervous system- nerve fibers innervate smooth and cardiac muscle and glands
- sympathetic and parasympathetic
neuroglia
non excitable
physical and biochemical support for neurons
occupy about half of the volume of the brain
four major types of glial cels serve as the connective tissue of the cns and as such help support the neurons both physically and metabolically
neuron
- excitable
- carry electrical signals
neuron is specialized to transmit electrical signals
cell body
axon
dendrites
mylin sheath
discontinuos sheath around the axon
composed of lipid and protein
nodes of ranvier: spaces between the segments of myelin sheath
- salutary conduction
salutary conduction
signal leaps from node to node
mylenaited nerve fibres have much faster conduction velocities than unmyleniated fibres
multiple sclerosis
autoimmune disease- body attacks myelin sheath within cns
break down in communication
exposed nerves can be destroyed irreversibly
fatigue, vision changes, numbness, loss of coordination, muscle weakness, cognitive dysfunction
synapse
the region where a neuron meets its target cell
chemical synapse: electrical signal converted to chemical signal for transmission to post synaptic cell
neuron structure
afferent neurons: carry impulses from the sensory receptors into spinal cord or brain
efferent neurons: transit impulses from the cns out of the effector organs- muscles and glands
interneurons: lie entirely within the cns. they account for 99% of all nerve cells
resting membrane potential
due to selective permeability characteristics of the nerve cell membrane a potential difference exists between the inside and outside
action potential
high concentration of positive sodium ions on the outside of the membrane causes it be electrically positive, while the inside is electrically negative, this causes sodium ions to rush to the inside of the nerve and reverses polarity
tetrodotoxtin
acts on the cns and pns
blocks sodium channels
prevents action potential
symptoms of poisoning: paresthesia in mouth then extremities
weakness, lack of coordination, paralysis, cyanosis
death within 4-6 hours
nerve to nerve synapses
nervous information is relayed across the synaptic cleft by means of a chemical transmitter substance
neural muscular junction
consists of axon terminals, motor end plates on the muscle membrane and schwas cell sheaths
spinal cord
The spinal cord is enlarged in two regions for innervation of the limbs:
a) The cervical enlargement which extends from the C4 through T1 segments of the spinal cord
b) The lumbosacral enlargement which extends from the T11 through L1 segments
of the spinal cord
plexus
a network on converging and diverging nerve fibres or blood vessels