Week 1 Review Flashcards
This is a review of - basic skin anatomy - common dermatoses - skin care - wound healing - PPE
solid elevation, minimal depth < 1.0 cm2
papule
solid elevation, minimal depth > 1.0 cm2
nodule
what secondary lesion can a papule or plaque become
scale
papule > plaque > scale
a fluid filled blister < 1.0 cm2
vesicle
a fluid filled blister > 1.0 cm2
bulla
what secondary lesion can vesicle or bulla become
erosion
flat discoloration > 1.0 cm2
patch
flat discoloration < 1.0 cm2
macule
secondary lesion involving tissue loss into the dermis
ulcer
crack in the skin
fissure
secondary lesion involving tissue loss into the epidermis
erosion
coagulation duration
few hours
inflammatory duration
2-5 days
proliferative duration
2 day-3 wks
remodeling duration
3 wks-2 yrs
primary function of coagulation
- platelet aggregate
- clot formation
- vasoconstriction
- cytokines to site
primary function of inflammatory
clean up debris
primary function of proliferative phase
- angiogenesis
- epithelialization
- contraction
primary function of remodeling phase
new collagen = increase tensile strength
key players in inflammatory phase
- mast cells
- macrophages
- neutrophils
how is the cross linking of fibronectin and fibrin important throughout the whole would healing process
creates a barrier to control bleeding and bacteria
which growth factors are responsible for ECM formation
- platelet derived growth factor
- epidermal growth factor
- transforming growth factor
what nutritional supplements are important for collagen synthesis
- protein
- zinc
- vitamin A, C
difference in dark female facial skin
- less atrophied area in epidermis
- minimal loss of elasticity
- more collagen fibers
- more, larger fibroblast
