Week 1: Oncology nursing 1 Flashcards
Epidemiology (4)
refers to the study of factors that may affect the health and illness of populations.
prevalence
The measurement of all cancer cases at a particular time
Number of persons with cancer at a given point in time / Total population living at that time
incidence
The number of newly diagnosed cases of cancer in a specified period of time in a defined population
Number of persons developing cancer in a specified period of time/Total population living at that time
mortality
The number of deaths attributed to cancer in a specified time period and in a defined population
Number of persons dying of cancer in a specified period of time/total population at time
survival
The proportion of cancer patients who are alive at a certain time after diagnosis, usually in terms of a 5 year survival rate. Survival analysis is the observation over time of persons with cancer and the calculation of their probability of dying over several time periods (for example, 5 or 10 year survival rates).
Cancer
disease where abnormal cells divide and multiply in an uncontrolled way
POST MITOTIC / PRE SYNTHESIS PHASE
which cells
start to make enzymes for DNA synthesis and
prepare for entry into the S phase.
SYNTHESIS
cells start replicates chromosomal DNA. Results in pairs of chromatid
POST SYNTHETIC / PRE MITOTIC
PHASE
growth and preparation for mitosis
MITOSIS
Cell division occurs
Go (RESTING) PHASE
cells are not actively dividing
The growth fraction
is the ratio of the total number of cells to the number of dividing cells. As a rule, the higher the growth fraction, the more rapidly tumour mass increases.
Doubling time
is the time taken for the tumour to double its volume; the average time for most solid tumours being 2-3 months. Tumours are usually not clinically detectable until they have doubled around 30 times
Gompertzian Tumour Growth Curve
which describes the decrease in cell doubling time as tumour progression occurs
‘intravasate’ and ‘extravasate.’
This means that cancer cells have the ability to enter and leave the circulatory and lymphatic systems