Week 1 Introduction and Homeostasis ✅ Flashcards

1
Q

What is homeostasis?

A

The state of a constant internal environment

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2
Q

What factors contribute to homeostasis?

A

Osmolarity, pH, O2 and temperature

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3
Q

What is the role of rough endoplasmic reticulum?

A

Process proteins

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4
Q

What is the role of soft endoplasmic reticulum?

A

Process lipids

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5
Q

What is the role of centrioles?

A

Cell division

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6
Q

What is the role of lysozomes?

A

Digestion

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7
Q

What is the role of golgi?

A

Packaging

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8
Q

What is the significance of hypertonic and hypotonic fluid with cells?

A

Fluid outside cells is hypertonic
Fluid inside cells is hypotonic

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9
Q

What is potassium involved in?

A

Cardiac contraction

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10
Q

Where are goblet cells located?

A

Intestines and lungs

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11
Q

What are the precursor of osteocytes?

A

Osteoblasts

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12
Q

What are blast cells?

A

Early cells

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13
Q

Why does a sperm cell have mitochondria in its head?

A

Movement

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14
Q

What is a totipotent cell?

A

Can form any cell

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15
Q

What is a pluripotent cell?

A

Can form >200 cell types

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16
Q

What is a multipotent cell?

A

A differentiated cell but can form multiple

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17
Q

What is a unipotent cell?

A

Can only form 1 cell type

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18
Q

What triggers DNA (genes) to make certain proteins?

A

Transcription factors/regulatory proteins

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19
Q

What are the features of a stem cell?

A

Self renew and differentiate into any cell

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20
Q

What does apoptosis mean?

A

Cell death

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21
Q

What is the role of cholesterol?

A

Regulate communication
Keep cell membranes fluid

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22
Q

What is endocytosis?

A

Engulf and bring into cell as a vesicle and recycle into cell membrane

23
Q

What kinds of molecules can cross cell layers easily and what examples?

A

Non-polar molecules e.g. O2, CO2, vitamins

24
Q

What is the purpose of trans-membrane protein channels?

A

To transport charged/polar molecules

25
Which part of the bilayer is hydrophilic and which is hydrophobic?
Hydrophilic (charged) head Hydrophobic tail (Tails are pointed together)
26
Are hormones and blood pressure under homeostatic control?
Yes
27
Is heart rate and body fat under homeostatic control?
No
28
Are blood gas levels under homeostatic control?
Yes
29
What are the features of negative feedback loop?
Stimulus → receptors → control centre → effectors
30
What does a baroreceptor measure?
Blood pressure
31
What does a chemoreceptor measure?
Blood gases
32
What does a thermoreceptor measure?
Temperature of the skin and organs
33
What does an osmoreceptor measure?
Osmolarity
34
What does a glucoreceptor measure?
Glucose
35
Give an example of a positive feedback situation
Childbirth - Oxytocin
36
What is the difference between positive and negative feedback?
Positive feedback moves the changes further away until it reaches an END POINT
37
When would the body temperature 'set point' be altered?
Fever
38
What effect does a high temperature have on the body?
Stimulate WBC production and activity
39
Why is the elderly and infants more susceptible to problems with heat?
The elderly's hearts are not as efficient in helping to regulate temperature Infants have a high surface area:volume so lose heat more easily
40
How do we get temperature 'in'?
Radiant heat Voluntary production of heat e.g. muscles Involuntary production of heat e.g. shivering
41
How do we get temperature 'out'?
Evaporation of sweat Conduction, convection
42
Which part of the brain is involved in temperature regulation?
Hypothalamus
43
What is an 'anticipatory' response?
Sympathetic response e.g. white coat syndrome with BP, about to run a race - heart racing before even set off
44
What is sensitisation?
Where there is more than 1 stimulus e.g. O2 and CO2 both affecting
45
What is 'feed forward' and what is an example?
Similar to anticipation response but at a lower threshold E.g. having a drink and stopping before osmoreceptors detect plasma osmolarity return
46
How does behaviour affect homeostasis?
Babies and infants may not be able to do certain tasks The elderly may forget to do certain tasks
47
How does 'accomodation' affect homeostasis?
Changes cell sensitivity
48
How does 'acclimation' affect homeostasis?
Long term adaptations - artificial means (lab)
49
How does 'acclimatisation' affect homeostasis?
Long term adaptations - natural means
50
How does 'genetic adaptation' affect homeostasis?
'Survival of fittest'
51
How does 'inherited adaptation' affect homeostasis?
Years of generations e.g. fat, cold environment
52
How does 'acquired adaptation' affect homeostasis?
1) Mins/hours - cold, pH etc 2) Days/weeks - sweat
53