Week 1: Introduction Flashcards
Hazard ratio
Ratio of risk of an outcome in one group to the risk of that outcome in another group occurring at any given interval of time
Relative risk
Ratio of the risk of an event in the exposure group to risk of that event in non-exposure group
Third variable problem
Confounding variable that leads to mistaken causal relationship
Types of third variables
- Confounder
- Moderator
- Mediator
Confounder
Influences both independent and dependent variables (not causally)
Moderator
Modifies strength of relationship btwn independent and dependent variables
Mediator
X causes the mediator (M) and M causes Y
Feeding trial
Participants provided w all meals, snacks, beverages
Traits of a feeding trial
High cost
High adherence
Short
High labour
Low generalizability
Randomized control intervention
Participants asked to follow a diet but not provided w meals
Traits of randomized control trial
Medium cost
Medium/low adherence
Medium length
High labour
Medium generalizability
Observational studies
Compare individuals who self-select to consume a specific diet
Traits of observational studies
Lower cost
Long
Lower labour
High generalizability
Parameters of metabolic health
- Blood sugar levels
- Triglycerides
- High density lipoprotein
- Blood pressure
- Waist circumference
Biomarker
Objective, quantifiable characteristics of biological processes