Week 1 Flashcards
Beta blocker overdose
Bradycardia, AV block, hypotension and DIFUSE WHEEZING
Hypoglycema, bronchospasm and neurological dysfunction (delerium)
Also cold and clamy extremities
=Sequre airway and give isotonic fluid boluses and IV atropine for treatment of hypotension and bradycardia
In patients with refactory or profound hypotension give IV glucagon
Glucagon increases intracellular levels of cAMP
Hypertrophic cardiomyopathy
Hyperkalemia
Normal pressure hydrocephalus
Hep A postexposure prophalaxis
Hep A or Hep A immune globulin in close personal contacts (sexual, houshold)
Child care contacts
Food preparation workers whose coworkers have been infected
Should be given within 2 weeks of exposure
AVNRT
Abrupt onset of regular tachycardia that resolves with cold water immersion
2 conduction pathways (slow and fast)
reentry mechanism
Vagal maneuvers increase parasympathetic tone in the heart and result in temporary slowing of conduction in AV node and increase in the AV node refractory period leading to termination of AVNRT
Hemodynamic measurements in shock
Hepatorenal syndrome
Prolonged high FIO2
Can cause oxygen toxicity as it can lead to the formation of proinflamatory oxygen free radicals and predispose to atelectasis as alveolar nitrogen is displaced, resulting in worsened oxygenation
No strict cutoff but levels less than 60% are considered safe
Aortic stenosis
Progressive fatigue with exertional lightheadedness and presyncope delayed carotid pulses and systolic murmur over the right upper sternal border
Severe AS is where signs show up (Valve area less than 1 cm2_
Diminished and delayed carotid pules (pulsus parvus et tardus)
Late-peaking crecendo-decrescendo systolic murmur
Soft and single S2
Reactive arthritis
Type of seronegative spondloarthropathy
Triad of nongonococcal urethritis, asymmetric oligoarthritis and conjunctivitis
OFten involves knee and sacroilliac spine
Mucucutaneous lesions and enthesitis (achilles tendon pain) are common findings
Synovial fluid analysis is usually sterile
NSAIDS are first line therapy during acute phase
Lacunar stroke

Acute Interstitial nephritis

Lead poisoning in adults

Evaluation of hyperthyroidism

Causes of urinary incontinence in the elderly

Crohn disease

Dermatofibroma
Due to fibroblast proliferation causing isolated or multiple lesions, most comonly in lower extremities
Etiology is unknown but some pateints may develop after trauma such as bug bites
Discrete, firm, hyperpigmented nodules that are usually less than 1 cm in diamter
Fiberous component that may cause dimplin in the center when the area is pinched (dimple or buttonhole sign)
Ichthyosis vulgaris
Chronic inherited skin disorder characterized by diffuse dermal scarring
Caused by mutation in filaggrin gene
Rough scale like skin
Worsens later in life and in winter
Porphyria cutanea tarda
SJS and TEN
Tinea versicolor
Teiogen effiuvuium
crystal-induced acute kidney injury
aspergilliosis
Cyanide accumulation and toxicity
Prolonged infusion of nitropurosside at high rates
Features of fibromyalgia, polymyositis and polymyalgia rheumatica
Cognitive impairment in elderly patients
Abnormal hemostasis in CRF
Platelet dysfunction most common
PT, PTT and Platelet count normal but BT prolonged
DDAVP (desmopressin) treatment of choice. Increases release of factor VII: von Willebrand factor multimers from endothelial storage sites
Platelet transfusion is not indicated because transfused platelets quickly become inactive
Length of time of liver transplant and infectious organism
ADH related causes of polyuria and polydipsia
Interstitial cysitis
Drugs associated with pancreatitis
Treatment of chronic stable angina
Cryoglobulinemia
Hypothyroidism metabolic abnormalities
Hyperlipidemia, hyponatremia and asymptomatic elevations of CK and serum transaminases
Statins can increase the risk for myopathy in poorly controlled hypothyroidism and should be given with caution in these patients
Colon cancer screening in patients at increased risk
Type 2 heparin-induced thrombocytopenia
Prevention of recurrent nephrolithiasis
Vaccines for chronic liver disease
Medications that improve survival in patients with LV systolic dysfunction
ACE inhibitors
ARBs
Beta blockers
Mieralcorticoid receptor antagonists (spironolactone and eplerone)
Ankylosing spondylitits
Conditions that alter TBG concentration
Theophylline toxicity
Narrow therapeutic index
CNS stimulation (headache, insomnia, seizures) GI disturbances and cardiac toxicity (arrhythmia)
Metabolized predominantly by the cytochrome oxidase system in the liver
Inhebition by conccurent ilness (cirrhosis, cholestasis, respiratory infections with fever) or drugs (cimetidine, ciprofloxacin, erythromycin, verapamil) can cause toxicity
Mechanical complications of acute MI
Restless legs syndrome
Pneumocystitis jiroveci pneumonia
ROC Curve
Causes of recurrent pneumonia
Pancreatic adenocarcinoma
Central retinal artery occlusion
Acute painless monocular vision loss
Most commonly begins as an embolized plaque from the ipsilateral carotid artery
Most patients develop significant permanent visual deficits.
Common causes of shoulder pain
General manifestations of hyperthyroidism
Patellofemoral pain syndrome
One of the most common causes of chronic, poorly localized anterior knee pain
Etiology is multifactorial and likely variable
Diagnosis based on clinical findings. Atrophy or weakness of the quadriceps or hip abductors is common, and rotational or varus/valgus malalignment may also be noted
Pain can often be provoked with tonic contraction of the quadriceps
Management includes avoiding triggering activities and strengthening exercises
Subdural Heamtoma
Huntington disease
ABGs of salicylate posoning
First respiratory alkalosis followed by anion gap metabolic acidosis
Low PaCo2
Low HCo3
Near normal pH because the two disturbances shift the pH in opposite directions
Nephrotic syndrome issues
The risk for atherosclerotic disease
hypercoagulability
Management of hypercalcemia
Multiple myeloma osteolytic bony metastases
Serum protein electrophoresis SPEP common screening detects elevated serum monoclonal (M-spike_
Bone marrow biopsy, more invasive, can then confirm diagnosis (more than 10 percent clonal plasma cells)
Thyrotoxicosis
Calcific uremic arteriolopathy
Types of PAH
Common variable immunodeficiency
Acute erosive gastropathy
Characterized by development of hemorrhagic lesions after ischemia or the exposure of gastric mucosa to various injurious agents (alcohol, aspirin, cocaine)
Subclavian Steal
OFten asymptomatic but may have symptoms of upper extremity ischemia (pain, fatigue, paresthesias) or vertebrobasilar insufficiency (dizziness, ataxia, dysequilibrium) that are worsened by upper extremity exercise
Myasthenic crisis
Acute pericarditis
CSF Fluid analysis
Effects of positioning in patient with pneumonia
Alveolar consolidation causes markedly impaired alveolar ventilation in the affected portion in the lung
THis results in hypoxemia due to right-t0-left intrapulmonary shunting of blood and extreme ventelation perfusion mismatch
HIV associated dementia
More likley in poorly controled HIV paitnets. CD4 less than 200
Characterized by subcortical symptoms early in course of disease
Subacute onset
Increased apathy and impaired attention
clinical features of primary hyperaldosteronism
Bechet disease
anorectal fistula
effect of maneuvers of hypertrophic cardiomyopathy
prosthetic joint infection
Exudative and transdative pleural effusions
Hypernatremia chart
Exertional heat stroke
nocardiosis
Approach to hyperbilirubinemia in adults
Asthma treatment
Splenic infarction
Uncommon usually arises in the setting of acute splenic artery occlusion
Etiologies include hypercoagulable state, embolic disease, or hemoglobinopathy
Pellegra
Niacin deficiency
Dermatitis of sun-exposed areas
Diarrhea
Dementia
Prolonged isoniazid therapy can occasionally cause
Basal ganglia (putaminal hemorrhage)
Hypertensive vasculopathy most common cause
Wilson disease
Drugs for neuropathic pain
Acute liver failure
Peak airway pressure (max pressure measured as the tital volume is being delivered) equals the sum of the resistive pressure (flow x resistance) and the plateau pressure
The plateau pressure is the pressure measured during an inspiratory hold maneuver when pulmonary airflow and thus restrictive pressure are both 0. It represents the sum of the elastic pressure and positive end-expiratory pressure
Waldenstrom macroglobulinemia
Causes of hypertension and hypokalemia chart
IgA nephropathy vs postinfectious glomerulonephritis