Week 1 Flashcards

1
Q

Neuron cell bodies size

A

15-20 um

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2
Q

Nissl bodies size

A

50 um

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3
Q

Gap/synapses between motor neuron vs membrane of muscle fibre

A

30-50nm

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4
Q

oligodendrocyte size

A

10 20 um

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5
Q

grey matter contains

A

soma, dendrites, axon terminal, synapses, glia

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6
Q

white matter contains

A

mylinated axon + glia

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7
Q

grey matter function

A

intergration of information

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8
Q

white matter function

A
  • impulses propagate here
  • information travel here
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9
Q

rER stands for?

A

rough endoplasmic reticulum

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10
Q

rER aslo called?

A

nissl body

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11
Q

rER important

A

protein synthesis

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12
Q

Neuron types

A
  • sensory vs motor
  • projection or stay still
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13
Q

sensory neuron

A
  • bipolar, pseudounipolar (split)
  • receive sensory information
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14
Q

short, stay within the local area

A

interneuron
golgi type 2

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15
Q

projection motor

A

long, out of brain and spinal cord (multipolar)
golgi type 1

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16
Q

contain cell bodies outside CNS

A

dorsal ganglion

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17
Q

action potential

A

membrane is polarised
inside more negative

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18
Q

type of input action potential

A

chemical: neurotransmitter
mechanical: pressure/ stretch of receptors at nerve ending in skin/muscle/bbb
thermal: thermo receptor
special sensory: taste. light proton…

19
Q

speed with myelin vs without

A

12-130 vs 0.5 - 2 (m/s)

20
Q

gap between motor neuron and plasma membrane

A

30 - 50 nm

21
Q

motor neuron support how many muscle cell

22
Q

neuroplasticity

A

change in shape + function + connection

23
Q

Cells in nervous system

A

glia
neuron
endothelial

24
Q

glia include

A

astrocyte
oligodendrocyte
microglia

25
Q

endothelial cell associates with

A

blood supply, supporting BBB

26
Q

CNS contains cells:

A

neuron
glia (oligodendrocyte, microglia, astrocyte)
endothelial

27
Q

PNS contains cells:

A

satelite cells
schwann cells

28
Q

myelinating cells

A

schwann + oligodendrocytes

29
Q

myelin sheath

A

fatty insulating layer

30
Q

myelinated axon

A

motor to skeletal muscle, sensory fine touch fromskin, proprioceptors body position

31
Q

unmyelinated axon

A

sensory pain from skin, motor heart + blood vessel

32
Q

neurilemma

A

outermost section of schwann cells surrounding axon

33
Q

oligodendrocyte

A

myelinate many axon

34
Q

schwann

A

need various to myelinate one

35
Q

astrocyte func

A
  • metabolic support for bbb
  • structural support for cns (brain + spinal cord)
  • endothelium for tight junction bbb (not tight only endothelial)
  • biochemical balance neuron (lactate)
  • scar (fill where neuron die)
  • support synapses form(buffer K+ prevent synaptic dysfunc)
  • glutamine for synthesis
36
Q

microglia

A

immune (survey CNS for pathogen)
injury: repair
prune synapses remodelling adult brain
tile grey matter
laser injury hippocampus
injury retina
change shape activate shorten thicken

phagocytosis
find eat digest

37
Q

ependymal cells

A

creating cerebrospinal fluid

38
Q

PNS satellite cells

A

surround neuron in
- sensory
- sympathetic
- parasympathetic
- ganglia
- regulate chemical environment

39
Q

myelin stain view?

A

oligodendrocyte bodies

40
Q

golgi silver stain

A

full morphology of neuron
include dendritic arbor + axon

41
Q

immunohistochemistry

A

distinguish diverse cell types
neuron vs glia
different glia

42
Q

morphology

A

shape of cells

43
Q

morphology types

A

bipolar, multipolar, unipolar..