week 1 Flashcards
fluid balance disturbances
name the 2 fluid compartments
intracellular space (ICF)
extracellular space (ECF)
intracellular fluid makes up ___ of total amount of fluids, mostly in __ ___ ___
2/3; skeletal muscle mass
extracellular fluid makes up ___ of total amount of fluid volume
1/3
ECF transcellular fluid ____
cerebrospinal fluid (CSF), pericardial, synovial, pleural, sweat, digestive, intraocular
what is CVP?
central venous pressure
where is CVP measured?
Right atrium
ECF fluid shifts into a space that doesn’t contribute to equilibrium
third spacing
does 3rd spacing mean fluid volume excess?
no
CVP is a ___ ____ indicator
fluid volume
low CVP = ___ FV
low
high CVP= ___ FV
high
define tonicity
the ability to make things move
define osmolarity
number of milliosmoles per liter of solution;
describes IV fluid due to being out of a liter
define osmolality
number of milliosmoles per kg of solvent;
weight
tonicity: isotonic=
fluid that has the same proportion of weight of particles and water; perfectly balanced
tonicity: hypotonic=
fewer particles, more water (dilute)
tonicity: hypertonic=
more particles, less water (concentrated)
hydrostatic pressure uses ___ force
pushing
osmotic pressure uses ___ force
pulling
first sign of increased hydrostatic pressure is ___
edema
fluid is made up of ___ & ____
solvent & solutes
diffusion, with or without facilitation, is a ____ transport mechanism
passive
name 3 passive transport mechanisms
filtration, diffusion, and osmosis
define osmosis
movement of water through a semi-permeable membrane; fluid moves not the particle
diffusion moves solutes from ___ concentration to ____ concentration
high —> lower
example of facilitated diffusion
glucose & insulin
examples of filtration
kidneys-urine
pitting edema
capillary exchange
what is sensible fluid loss and give an example
loss that can be perceived by the senses and can be measured; urine
what is insensible fluid loss and give an example
losses can neither be perceived nor measured directly; sweat, respiratory vapor
Name 5 homeostatic mechanisms
- baroreceptors
- renin-angiotensin-aldosterone system
- antidiuretic hormone (ADH)
- thirst
- Brain natriuretic Peptides (BNP)
in normal conditions, kidneys produce ____ of urine per day
1-2 liters
indication of how kidneys are doing
GFR glomerular filtration rate