proficiency Flashcards

1
Q

Acyclavir; PC?

A

Antiviral

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2
Q

Acyclavir; MOA?

A

Inhibits DNA synthesis and viral replication

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3
Q

Acyclavir; Indic?

A

Herpes (Shingles and Chickenpox) Bells Palsy

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4
Q

Acyclavir; Admin?

A

Oral and IV

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5
Q

Acyclavir; Effects?

A

Acute Kidney Injury, neurotoxicity, thrombotic microangiopathy

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6
Q

Acyclavir; MP?

A

Hydration, urinalysis, BuN, creatinine, output

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7
Q

Amiodarone; PC?

A

antiarrhythmic, agent class 3

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8
Q

Amiodarone; MOA?

A

inhibits adrenergic stimulation, prolongs action potential and refractory period

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9
Q

Amiodarone; Indic?

A

ventricular arrhythmias (VFib) (VTach) / A Fib

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10
Q

Amiodarone; Admin?

A

Oral, IV, less than or equal to 2 mg/mL

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11
Q

Amiodarone; Effects?

A

Bradycardia, hypotension, N/V, pulmonary toxicity

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12
Q

Amiodarone; MP

A

BP, HR, EKG, (Potassium/ magnesium)

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13
Q

Baclofen; PC?

A

Skeletal muscle relaxant

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14
Q

Baclofen; MOA?

A

inhibits transmission of mono/poly synaptic reflexes at spinal cord level

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15
Q

Baclofen; Indic?

A

spasticity / hiccups, muscle spasms

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16
Q

Baclofen; Admin?

A

Bolus (50 mcg/ mL); oral (granules/ solution)

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17
Q

Baclofen; Effects?

A

N/V, asthenia, confusion, dizziness, headache, hypotonia

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18
Q

Baclofen; MP?

A

EEG, S/S of withdrawal altered mental status, spasticity, hallucination, fever, tachycardia

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19
Q

Benazepril; PC?

A

Angiotensin - converting enzyme (ACE) inhibitor, antihypertensive

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20
Q

Benazepril; MOA?

A

Inhibition of angiotensin 1 being converted to 2 - increase of plasma renin activity and reduction in aldosterone secretion

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21
Q

Benazepril; Indic?

A

Hypertension

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22
Q

Benazepril;Admin?

A

Oral

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23
Q

Benazepril; Effects?

A

Acute Kidney Injury, angioedema, cough, hyperkolemia

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24
Q

Benazepril; MP?

A

BP, BuN, Creatinine, electrolytes, airway

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25
Q

Bisoprolol; MOA?

A

Competitively blocks beta-1 receptors

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26
Q

Bisoprolol; PC?

A

Beta 1 Blocker, antihypertensive

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27
Q

Bisoprolol; Indic?

A

Hypertension/ angina, A Fib/ Flutter, Heart Failure with reduced EF, ventricular arrhythmia,

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28
Q

Bisoprolol; Admin?

A

oral without to regard to meals, smallest size 5 mg

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29
Q

Bisoprolol; Effects?

A

bradyarrhythmia, brnochospams, CNS. masking hypoglycemia, withdrawal

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30
Q

Bisoprolol; MP?

A

BP, HR, EKG, S/S of bronchospasm, glucose, mental alertness

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31
Q

bumetanide PC

A

loop diuretic; antihypertensive

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32
Q

Bumetanide MOA

A

inhibits reabsorption of sodium & chloride in loop of henle

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33
Q

Bumetanide USE

A

edema or volume overload

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34
Q

bumetanide ADMIN

A

IV-slowly 0.5 to 1mg over 1-2 mins
oral- w/ or w/o food, 1-2 days in between

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35
Q

Bumetanide A.EFFECTS

A

AKI, electrolyte/fluid loss, ototoxicity, hypo-chloremia/kalemia, hyperuricemia

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36
Q

Bumetanide MP

A

BP, electrolytes, kidney function, I/O

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37
Q

bupropion PC

A

dopamine/norepinephrine-reuptake inhibitor; antidepressant

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38
Q

bupropion MOA

A

weak inhibitor of the neuronal uptake of dopamine/norepinephrine

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39
Q

bupropion USE

A

MDD, SAD smoking cessation/ ADHD, bipolar, depressive episode

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40
Q

bupropion ADMIN

A

oral-do not crush, immediate release- 3/4 daily w/ 6hrs inbetween

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41
Q

bupropion A.EFFECTS

A

mania (hypo), CNS stimulation, abnormal thinking, seizure, ocular, wt loss

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42
Q

bupropion MP

A

BP, body wt, suicidality, renal/hepatic function, HR

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43
Q

captopril PC

A

ACE inhibitor; antihypertensive

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44
Q

captopril USE

A

acute coronary syndrome, HF w/ reduced EF, HTN, CKD/ aldosteronism

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45
Q

captopril ADMIN

A

oral- @ least 1 hour before meals

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46
Q

captopril A.EFFECTS

A

AKI, angioedema, cough, hyperkalemia, hematologic effects

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47
Q

captopril MP

A

BP, BUN, creatinine, electrolytes, airway obstruction

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48
Q

carbamazepine PC

A

antimanic/ antiseizure agent

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49
Q

carbamazepine MOA

A

depress activity in nucleus ventralis of thalamus or decrease synaptic transmission

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50
Q

carbamazepine USE

A

bipolar, focal/generalized seizures, neuropathic pain/
bipolar major depression

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51
Q

carbamazepine ADMIN

A

w/food, suspension

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52
Q

Dorzolamide; PC

A

Carbonic Anhydrase Inhibitor, Antiglaucoma

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53
Q

Dorzolamide; MCA

A

Inhibition of enzyme carbonic anhydrase II & IV in ciliary epithelium

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54
Q

carbamazepine MP

A

CBC, renal/liver function, ophthalmic exam

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55
Q

losartan ADMIN

A

w/o regards to meals but @ same time everyday

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56
Q

losartan A.EFFECTS

A

AKI, hyperkalemia

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57
Q

Dorzolamide; Indic

A

ocular hypertension / open- angel glaucoma

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58
Q

Dorzolamide; Admin

A
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59
Q

Dorzolamide; Effects

A

Burning, Discomfort, Stinging

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60
Q

Dorzolamide; MP

A

Eye Exams, IOP

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61
Q

Fentanyl; PC

A

Opioid, analgesic

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62
Q

Fentanyl; MOA

A

Binds with stereospecific receptors at sites without CNS

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63
Q

Fentanyl; Indic

A

Pain management

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64
Q

Fentanyl; Admin

A

IM / IV - slowly over 1 to 2 minutes

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65
Q

Fentanyl; Effects

A

Constipation, wD, respiratory depression, peripheral edema, dehydration

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66
Q

Fentanyl; MP

A

Pain, Respiratory/ Mental status, BP, HR, GI symptoms

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67
Q

Glipizide; PC

A

Antidiabetic agent, sulfonylurea,

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68
Q

Glipizide; MOA

A

Stimulates insulin release from pancreatic beta cells, reduces glucose output from liver

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69
Q

Glipizide; Indic

A

DM II

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70
Q

Glipizide; Admin

A

30 minutes before meal

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71
Q

Glipizide; A.Effects

A

Cardiovascular, hyperglycemia, sulfa allergy

72
Q

Glipizide; MP

A

S/S hypoglycemia (fatigue, excessive hunger, sweating, numbness of extremities)

73
Q

Hydroxyzine; PC

A

Histamine H 1 Antagonist, antiemetic

74
Q

Hydroxyzine; MOA

A

Competes with histamine H1 receptor sites on effector cells

75
Q

losartan MP

A

BP, electrolytes (potassium), creatinine, BUN

76
Q

metoclopramide PC

A

serotonin 5-HT4 receptor agonist (antiemetic) dopamine agonist

77
Q

metoclopramide MOA

A

blocks dopamine & serotonin receptors; enhances response to acetylcholine

78
Q

metoclopramide USE

A

chemo n/v, diabetic gastroparesis/
GERD

79
Q

metoclopramide ADMIN

A

IM/IV, nasal, oral- 30mins before meals

80
Q

metoclopramide A.EFFECTS

A

CNS depression, extrapyramidal symptoms

81
Q

metoclopramide MP

A

signs of TD, extrapyramidal symptoms, mental status

82
Q

clindamycin PC

A

antibiotic, lincosamide

83
Q

clindamycin MOA

A

inhibits bacterial protein synthesis

84
Q

clindamycin USE

A

infections- bone, joint, gynecological, intraabdominal, lower respiratory, septicemia

85
Q

clindamycin ADMIN

A

IM-rotate sites
IV- 30mg/min
oral- w/full glass of water

86
Q

clindamycin A.EFFECTS

A

c-dif

87
Q

clindamycin MP

A

bowel freq
liver/renal function

88
Q

mirtazapine PC

A

alpha-2 antagonist, antidepressant

89
Q

mirtazapine MOA

A

increased release of norepinephrine & serotonin

90
Q

carbamazepine A.EFFECTS

A

blood dyscrasias, cardiac (HF), hyponatremia, suicidal, n/v, ataxia, dizzy/drowsiness

91
Q

cimetidine PC

A

histamine H2 antagonist

91
Q

cimetidine MOA

A

inhibition of H2 receptors of gastric parietal cells resulting in reduced gastric secretions

92
Q

cimetidine USE

A

GERD, heartburn, peptic ulcer disease/
interstitial cystic/bladder cancer

93
Q

cimetidine ADMIN

A

w/meals

94
Q

cimetidine MP

A

CBC, gastric PH, signs of confusion, GI bleeding

95
Q

mirtazapine USE

A

MDD/
h/a, panic disorder

96
Q

Hydroxyzine; Indic

A

Anxiety, pruritus, urticaria

97
Q

Hydroxyzine; Admin

A

only IM or oral

98
Q

Hydroxyzine; Effects

A

CNS depression, QT prolongation, acute generalized exanthematous putulosis

99
Q

Hydroxyzine; MP

A

Mental status, BP, S/S allergies

100
Q

Losartan; PC

A

Angiotensin II receptor blocker, antihypertensive

101
Q

Losartan; MOA

A

Blocks vaso constrictor and aldosterone- secreting effects angiotensin II

102
Q

Losartan; Indic

A

HTN, proteinic CKD (non-diabetic), HF with reduced EF

103
Q

mirtazapine ADMIN

A

oral tablet w/o regards to meals, don’t crush

104
Q

mirtazapine A.EFFECTS

A

mania (hypo), movement disorders, orthostatic hypotension, SI, wt gain, sexual dysfunction, constipation, xerostomia, drowsiness

105
Q

mirtazapine MP

A

CBC, renal/hepatic function, weight

106
Q

misoprostol PC

A

prostaglandin

107
Q

misoprostol MOA

A

synthetic- replaces protective prostaglandins consumed w/p-inhibiting therapies

108
Q

misoprostol USE

A

prevention gastric ulcers, termination of pregnancy/
labor induction

109
Q

misoprostol ADMIN

A

oral tabs

110
Q

misoprostol A.EFFECTS

A

abd pain, diarrhea, DO NOT USE DURING PREG

111
Q

misoprostol MP

A

fetal HR, uterine activity, blood loss

112
Q

morphine PC

A

analgesic opioid

113
Q

morphine MOA

A

binds to opioid receptors in CNS

114
Q

morphine USE

A

pain management/
dyspnea, cough

115
Q

morphine ADMIN

A

oral-don’t crush
IV slow over 4-5 mins

116
Q

morphine A.EFFECTS

A

constipation , neurotoxicity, pruritus, respiratory depression, WD

117
Q

morphine MP

A

pain control, respiratory/mental status, BP, signs of misuse

118
Q

nortriptyline PC

A

tricyclic antidepressant

119
Q

nortriptyline MOA

A

increase synaptic concentration of serotonin &/or norepinephrine

120
Q

nortriptyline USE

A

MDD/
h/a, IBS, migraine, smoking cessation, pain

121
Q

nortriptyline ADMIN

A

oral- w/o regards to food

122
Q

nortriptyline A.EFFECTS

A

SI, CNS depression, ocular effects, orthostatic hypotension, hyponatremia

123
Q

nortriptyline MP

A

sodium, BP, HR, mental status, weight,

124
Q

ondansetron PC

A

selective 5-HT3 receptor antagonist; antiemetic

125
Q

ondansetron MOA

A

blocks serotonin

126
Q

ondansetron USE

A

chemo n/v/
diarrhea

127
Q

ondansetron ADMIN

A

oral, IM/IV

128
Q

ondansetron A.EFFECTS

A

constipation, h/a, QT prolongation

129
Q

ondansetron MP

A

EKG, heart failure, potassium/magnesium

130
Q

pentoxifylline PC

A

blood viscosity reducer agent

131
Q

pentoxifylline MOA

A

increases blood flow to affected microcirculation

132
Q

pentoxifylline USE

A

intermittent claudication (pain in legs due to reduced circulation) /
venous leg ulcers

133
Q

pentoxifylline ADMIN

A

oral w/food, don’t crush

134
Q

pentoxifylline MP

A

renal function, hemoglobin, hematocrit,

135
Q

phenobarbital PC

A

barbiturate; antiseizure

136
Q

phenobarbital MOA

A

depress sensory cortex

137
Q

phenobarbital USE

A

sedation, seizures/
alcohol WD

138
Q

phenobarbital ADMIN

A

IV, IM, orally

139
Q

phenobarbital A.EFFECTS

A

respiratory depression, SI, hypotension, bradycardia, drowsiness, vertigo

140
Q

phenobarbital MP

A

s/s suicidality, CNS status, phenobarbital concentration

141
Q

pioglitazone PC

A

thiazolidinedione; antidiabetic

142
Q

pioglitazone MOA

A

improving target cell response to insulin

143
Q

pioglitazone USE

A

DM II

144
Q

pioglitazone ADMIN

A

oral- w/o regards to meals

145
Q

pioglitazone A.EFFECTS

A

bladder cancer, fractures, HF/edema, hepatic failure, hypoglycemia, URI

146
Q

pioglitazone MP

A

s/s HF, rapid wt gain

147
Q

pravastatin PC

A

HMG-CoA reductase inhibitor; antilipemic

148
Q

pravastatin MOA

A

inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A

149
Q

pravastatin USE

A

hypercholesterolemia, prevention atherosclerotic/
post heart/kidney transplant,

150
Q

pravastatin A.EFFECTS

A

URI, musculoskeletal pain, hepatic effects

151
Q

pravastatin ADMIN

A

oral w/o regards to meals

152
Q

pravastatin MP

A

lipid panel

153
Q

sulfasalazine PC

A

5-aminosalicylic acid derivative; antirheumatic

154
Q

sulfasalazine MOA

A

modulates chemical mediators of inflammatory response

155
Q

sulfasalazine USE

A

rheumatoid arthritis, ulcerative colitis/
crohns, psoriatic arthritis, ankylosing spondylitis,

156
Q

sulfasalazine ADMIN

A

oral- after meals

157
Q

sulfasalazine A.EFFECTS

A

n/v/d, abdominal pain, blood dyscrasias (disorders), rash, h/a

158
Q

sulfasalazine MP

A

CBC w/differential

159
Q

sumatriptan PC

A

serotonin 5-HT 1B,1D receptor agonist; antimigraine

160
Q

sumatriptan MOA

A

selective agonist for serotonin, causes vasoconstriction reduces inflammation

161
Q

sumatriptan USE

A

cluster h/a, migraine/
cyclic vomiting syndrome

162
Q

sumatriptan ADMIN

A

NOT IV/IM!!
subq, [intranasal powder, solution, spray]

163
Q

sumatriptan A.EFFECTS

A

cardiac arrhythmias/events, strokes, dizziness, drowsiness, vertigo, serotonin syndrome,

164
Q

sumatriptan MP

A

mental status, BP, neuromuscular changes, GI symptoms, seizures,

165
Q

temazepam PC

A

benzodiazepine

166
Q

temazepam MOA

A

binds to receptors on postsynaptic GABA neuron @ several sites

167
Q

temazepam USE

A

insomnia

168
Q

temazepam ADMIN

A

oral capsule

169
Q

temazepam MP

A

respiratory/cardiovascular status

170
Q

verapamil PC

A

calcium channel blocker; anti-anginal, arrhythmic, hypertensive

171
Q

verapamil MOA

A

inhibits calcium ion from entering slow channels, relaxes coronary smooth muscle,

172
Q

verapamil USE

A

angina, a fib/flutter, HTN, supraventricular tachycardia, chest pain, h/a, migraine,

173
Q

verapamil ADMIN

A

oral, IV push over less than/equal to 2 mins

174
Q

verapamil A.EFFECTS

A

acute decompensated HF, bradyarrhythmias, h/a, hepatic effects

175
Q

verapamil MP

A

BP, HR, liver/kidney function