Week 1

Question 1

study of what drug does to body and what the body does to the drug

Answer 1

Pharmacology

Question 2

active ingredient of a medicine. it mimics and blocks

Answer 2

drug

Question 3

names used for drug

Answer 3

chemical, generic, trade

Question 4

properties of an ideal drug

Answer 4

safety and effectiveness

Question 5

max non-toxic plasma concentration minus min effective plasma concentration

Answer 5

therapeutic range

Question 6

ratio of dose of drugs. the higher it is the better

Answer 6

therapeutic index

Question 7

safe drugs have a wide therapeutic range and high TI

Answer 7

true

Question 8

study of functional changes that result from a disorder or a disease

Answer 8

pathophysiology

Question 9

a condition not easily diagnosed.
disturbance or abnormal function indicating incomplete health
e.g: major depressive disorder

Answer 9

disorder

Question 10

easiest to identify.
particular pathophysiology condition with characteristics features
e.g: COPD

Answer 10

disease

Question 11

indicators of structural and functional changes associated with the disease.
specific or non-specific

Answer 11

clinical manifestations

Question 12

syndrome

Answer 12

set of specific signs and symptoms that occur together

Question 13

sign

Answer 13

objective measurement

Question 14

symptoms

Answer 14

subjective - patient description

Question 15

study of causes, distribution and control of disease in populations

Answer 15

epidemiology

Question 16

number of newly diagnosed cases of a disease - today

Answer 16

incidence

Question 17

prevalence

Answer 17

number of newly and previously diagnosed cases of disease - today + before

Question 18

proportion of the population affected by the disease - loss of life quality

Answer 18

morbidity

Question 19

co-morbidity

Answer 19

presence of another disease in the same or group of patients

Question 20

mortality

Answer 20

death rate from the disease

Question 21

decline in function due to genetic and environmental factors

Answer 21

cellular ageing

Question 22

atrophy

Answer 22

decrease in size

Question 23

hypertrophy

Answer 23

increase in size

Question 24

hyperplasia

Answer 24

increase in number

Question 25

metaplasia

Answer 25

change in different cell type

Question 26

dysplasia

Answer 26

irregular cell growth

Question 27

apoptosis

Answer 27

programmed cell death

physiological process

Question 28

necrosis

Answer 28

cell death due to injury

pathological process

Question 29

pharmacokinetics

Answer 29

how the body helps or hinder the drug to work

Question 30

pharmacodynamics

Answer 30

how the drugs affects the body

Question 31

agonists

Answer 31

trigger receptor to do what it normally does

Question 32

antagonists

Answer 32

block receptors from doing what they normally do

Question 33

Absorption

Answer 33

only applies to oral route

absorbs through GIT then portal vein then 1st pass effect in liver

Question 34

distribution

Answer 34

movement of drug from bloodstream to target tissue

Question 35

metabolism

Answer 35

breakdown or activating drugs

Question 36

excretion

Answer 36

elimination of wastes
water soluble - kidney
fat soluble - bile

Question 37

half-life

Answer 37

how long it takes for the body to cut the amount of drug in the system by half

Question 38

treatment for poisoning

Answer 38

supportive care, identification of poison, prevention of further absorption, promotion of poison removal and use of specific antidotes

Question 39

what specific antidotes?

Answer 39

acetylcysteine

naloxone or narcan for opioids

Question 40

prevention of further absorption

Answer 40

activated charcoal and gastric lavage