weak areas

Question 1

how do the constituents of the bacterial cell wall lead to an innate immune response

Answer 1

pathogen associated molecular patterns are detected by pattern recognition receptors on oral keratinocytes

intracellular signalling cascade activates specific transcription factors which in turn control expression of inflammatory mediators which are then released from cells

these molecules then dictate the immune response in a variety of ways including controlling influx of immune cells and expression of molecules to eliminate the pathogenic threat

Question 2

what are some pathogen associated molecular pattern examples

Answer 2

lps
cilia
flagella
bacterial dna

Question 3

what is an example of pattern recognition receptor

Answer 3

toll like receptors

Question 4

cd4 t cell subsets and their functions

Answer 4

t follicular helper cells - communicate with other cells, stimulate b cells to produce antibodies, activate other t cells

t suppressor cells - maintain immune tolerance, shut down t cell mediated immunity

th1 - promote activation of macrophages