WBCs/ Leukocytes Flashcards
Granulocytes in the body
Basophils
Eosinophils
Neutrophils
Increases when you have Parasitic infestation
Eosinophils
First to arrive at the site of invasion
Neutrophils
Lifespan of Neutrophils
6-10 hours to few days (5.4 days)
Important in controlling your allergic inflammatory response
Eosinophils
Contain a protein that is highly toxic to large parasitic worms
Eosinophils
When they die, their activity and death in large numbers, form pus
Neutrophils
Fatty signaling molecules that are first found in leukocytes
Leukotrienes
Trigger contractions in the smooth muscles lining the trachea; their overproduction is a major cause of inflammation in asthma and allergic rhinitis
Leukotriene D4
Involve also in hypersensitivity response
Eosinophils
a monoamine neurotransmitter, thought to be a contributor to feelings of well-being and happiness
Serotonin
an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter
Histamine
Lifespan of Eosinophils
8 to 12 days
Releases histamine, bradykinin, serotonin, leukotrienes in acute hypersensitivity reaction
Basophils
increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues
Histamine
a peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to lower
Bradykinin
Controls the release of serotonin & histamine
Eosinophils
Mature forms of blood monocytes
Macrophage
Kidney shaped that mature into macrophages when in the body tissues
Monocytes
General scavenger cells of the body
Macrophage
Overproduction of these molecules is a major cause of inflammation in asthma and allergic rhinitis
Leukotrienes
One important role of these cells is the removal of necrotic cellular debris in the lungs
Macrophage
Share the “vacuum cleaner” (phagocytosis) function of neutrophils, but are much longer lived as they have an extra role
Monocytes
Responsible for cell-mediated immunity
T cells