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IMMUNOLOGY > WBCs/ Leukocytes > Flashcards

WBCs/ Leukocytes Flashcards

1
Q

Granulocytes in the body

A

Basophils
Eosinophils
Neutrophils

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2
Q

Increases when you have Parasitic infestation

A

Eosinophils

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3
Q

First to arrive at the site of invasion

A

Neutrophils

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4
Q

Lifespan of Neutrophils

A

6-10 hours to few days (5.4 days)

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5
Q

Important in controlling your allergic inflammatory response

A

Eosinophils

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6
Q

Contain a protein that is highly toxic to large parasitic worms

A

Eosinophils

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7
Q

When they die, their activity and death in large numbers, form pus

A

Neutrophils

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8
Q

Fatty signaling molecules that are first found in leukocytes

A

Leukotrienes

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9
Q

Trigger contractions in the smooth muscles lining the trachea; their overproduction is a major cause of inflammation in asthma and allergic rhinitis

A

Leukotriene D4

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10
Q

Involve also in hypersensitivity response

A

Eosinophils

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11
Q

a monoamine neurotransmitter, thought to be a contributor to feelings of well-being and happiness

A

Serotonin

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12
Q

an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter

A

Histamine

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13
Q

Lifespan of Eosinophils

A

8 to 12 days

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14
Q

Releases histamine, bradykinin, serotonin, leukotrienes in acute hypersensitivity reaction

A

Basophils

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15
Q

increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues

A

Histamine

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16
Q

a peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to lower

A

Bradykinin

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17
Q

Controls the release of serotonin & histamine

A

Eosinophils

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18
Q

Mature forms of blood monocytes

A

Macrophage

19
Q

Kidney shaped that mature into macrophages when in the body tissues

A

Monocytes

20
Q

General scavenger cells of the body

A

Macrophage

21
Q

Overproduction of these molecules is a major cause of inflammation in asthma and allergic rhinitis

A

Leukotrienes

22
Q

One important role of these cells is the removal of necrotic cellular debris in the lungs

A

Macrophage

23
Q

Share the “vacuum cleaner” (phagocytosis) function of neutrophils, but are much longer lived as they have an extra role

A

Monocytes

24
Q

Responsible for cell-mediated immunity

A

T cells

25
Q

Make antibodies that can bind to pathogens, block pathogen invasion, activate the complement system, and enhance pathogen destruction

A

B cells

26
Q

Large granular lymphocytes

A

NK cells

27
Q

Main function is to process antigen material and present it on the cell surface to the T cells of the immune system

A

Dendritic cells

28
Q

Can be stimulated to degranulate by direct injury, cross-linking of Immunoglobulin E (IgE) receptors, or by activated complement proteins.

A

Mast Cells

29
Q

Regulatory proteins that are produced during all phases of an immune response

A

Cytokines

30
Q

Essential for humoral immunity

A

B cells

31
Q

Primary cell of the immune system that represents 25 – 35% of blood leukocytes

A

Lymphocytes

32
Q

Contains many granules rich in histamine and heparin

A

Mast cells

33
Q

Group of cytokines that protect neighboring cells from invasion by intracellular parasites, including viruses, rickettsia, malarial parasites and other organisms

A

Interferons

34
Q

Mediate chemoattraction (chemotaxis) between cells

A

Chemokines

35
Q

Group of genes responsible for the recognition of self from non-self

A

MAJOR HISTOCOMPATIBILITY COMPLEX

36
Q

3 Major Types:

A

MHC 1/ HLA
MHC2
MHC 1 &2

37
Q

Also known as accessory cells

A

Dendritic cells

38
Q

Group of cytokines that are mediator of the inflammatory response

A

Interleukin 1/ IL 1

39
Q

Nonspecific effector cells that can kill tumor and virus infected cells
that do not need to recognize a specific antigen before being activated

A

NK cells

40
Q

Group of cytokines that are necessary for the proliferation and function of helper T, cytotoxic T, B cells, and NK cells

A

Interleukin 2

41
Q

Factors that support the growth of cells in semisolid media

A

Colony stimulating factors

42
Q

NK cells are activated in response to a family of cytokines called?

A

Interferons

43
Q

These are cells that are present in those tissues that are in contact with the external environment, such as the skin

A

Dendritic Cells

IMMUNOLOGY (4 decks)

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