WBCs/ Leukocytes Flashcards

1
Q

Granulocytes in the body

A

Basophils
Eosinophils
Neutrophils

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2
Q

Increases when you have Parasitic infestation

A

Eosinophils

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3
Q

First to arrive at the site of invasion

A

Neutrophils

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4
Q

Lifespan of Neutrophils

A

6-10 hours to few days (5.4 days)

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5
Q

Important in controlling your allergic inflammatory response

A

Eosinophils

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6
Q

Contain a protein that is highly toxic to large parasitic worms

A

Eosinophils

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7
Q

When they die, their activity and death in large numbers, form pus

A

Neutrophils

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8
Q

Fatty signaling molecules that are first found in leukocytes

A

Leukotrienes

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9
Q

Trigger contractions in the smooth muscles lining the trachea; their overproduction is a major cause of inflammation in asthma and allergic rhinitis

A

Leukotriene D4

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10
Q

Involve also in hypersensitivity response

A

Eosinophils

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11
Q

a monoamine neurotransmitter, thought to be a contributor to feelings of well-being and happiness

A

Serotonin

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12
Q

an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter

A

Histamine

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13
Q

Lifespan of Eosinophils

A

8 to 12 days

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14
Q

Releases histamine, bradykinin, serotonin, leukotrienes in acute hypersensitivity reaction

A

Basophils

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15
Q

increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues

A

Histamine

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16
Q

a peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to lower

A

Bradykinin

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17
Q

Controls the release of serotonin & histamine

A

Eosinophils

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18
Q

Mature forms of blood monocytes

A

Macrophage

19
Q

Kidney shaped that mature into macrophages when in the body tissues

20
Q

General scavenger cells of the body

A

Macrophage

21
Q

Overproduction of these molecules is a major cause of inflammation in asthma and allergic rhinitis

A

Leukotrienes

22
Q

One important role of these cells is the removal of necrotic cellular debris in the lungs

A

Macrophage

23
Q

Share the “vacuum cleaner” (phagocytosis) function of neutrophils, but are much longer lived as they have an extra role

24
Q

Responsible for cell-mediated immunity

25
Make antibodies that can bind to pathogens, block pathogen invasion, activate the complement system, and enhance pathogen destruction
B cells
26
Large granular lymphocytes
NK cells
27
Main function is to process antigen material and present it on the cell surface to the T cells of the immune system
Dendritic cells
28
Can be stimulated to degranulate by direct injury, cross-linking of Immunoglobulin E (IgE) receptors, or by activated complement proteins.
Mast Cells
29
Regulatory proteins that are produced during all phases of an immune response
Cytokines
30
Essential for humoral immunity
B cells
31
Primary cell of the immune system that represents 25 – 35% of blood leukocytes
Lymphocytes
32
Contains many granules rich in histamine and heparin
Mast cells
33
Group of cytokines that protect neighboring cells from invasion by intracellular parasites, including viruses, rickettsia, malarial parasites and other organisms
Interferons
34
Mediate chemoattraction (chemotaxis) between cells
Chemokines
35
Group of genes responsible for the recognition of self from non-self
MAJOR HISTOCOMPATIBILITY COMPLEX
36
3 Major Types:
MHC 1/ HLA MHC2 MHC 1 &2
37
Also known as accessory cells
Dendritic cells
38
Group of cytokines that are mediator of the inflammatory response
Interleukin 1/ IL 1
39
Nonspecific effector cells that can kill tumor and virus infected cells that do not need to recognize a specific antigen before being activated
NK cells
40
Group of cytokines that are necessary for the proliferation and function of helper T, cytotoxic T, B cells, and NK cells
Interleukin 2
41
Factors that support the growth of cells in semisolid media
Colony stimulating factors
42
NK cells are activated in response to a family of cytokines called?
Interferons
43
These are cells that are present in those tissues that are in contact with the external environment, such as the skin
Dendritic Cells