WBC Anomaly Flashcards
WBC anomaly seen in severe infections, chemical poisonings and leukemia
clue: marami itong butas 😂
vacuolated neutrophil
Hairy cell leukemias are usually seenin patients with _____.
Cancer
WBC Anomaly that is usually found in Megaloblastic Anemia
a. Czediak- higashi syndrome
b. vacuolated wbc
c. hypersegmented neutrophil
C. hypersegmented neutrophil
Hypersegmented neutrophil has _____ lobes
5-10 lobes
WBC anomaly due to rupture of wbc with bare nucleus
Smudge cells
What type of wbc anomaly wherein the appearance of the inclusions is transient only?
Dohle bodies
What is the most affected organ in LE cell anomaly?
Kidney
LE cell is classified as ________ disease.
Autoimmune
What type of phagocytic wbc is found in LE cell?
Neutrophil
Type of wbc anomaly seen in DRUG SENSITIVITY
Tart cells
This wbc anomaly is often associated with scarlet fever
Dohle bodies
Prescence of holes or vacuoles in the cytoplasm is a sign of _______ and it is usually found in ________.
degeneration; vacuolated wbc
Type of wbc anomaly wherein lymphocytes have notched, lobulated or segmented or clover leaf like nucleus
Clue: Katunog ng taong nakasakay sa english 😂
Reider cells
type of wbc anomaly characterized by the failure of the nucleus of neutrophil to segment or lobulate
clue: eyeglasses appearance
Pelger huet anomaly
Give two associated disease of Reider cell
Chronic lymphocytic or lymphatic leukemia
WBC anomaly that are periodic acid schiff (pas) positive
Dohle bodies
Vacuolated wbc may be found in normal blood smear if the smear is made from _________ which is over ____ hrs. old
oxalated blood; 2 hrs
A phagocytic wbc that has ingested an altered, homogenous globular nuclear mass of a destroyed cell
Lupus erythematosus cell
Wbc anomaly associated with Malignant myeloproliferative neoplasm
true pelger huet anomaly
Wbc anomaly consists of rRNA usually in the periphery of cells
clue: department of labor and employee mehehehe
Dohle bodies
Dohle bodies may also be found within ______ nuclues.
BAND
WBC anomaly that reflect sudden storage pool disease
Dohle bodies
What type of wbc anomaly wherein dohle bodies may also be seen?
May-hegglin anomaly
type of WBC anomaly characterized by giant cytoplasmic granules in the phagocytes and lymphocytes
czediak-higashi syndrome
what is the color of toxic granulations?
dark blue – black
WBC anomaly characterized by dense azurophilic granulations in all types of leukocytes
alder-reilly anomaly
type of WBC anomaly where in granulations usually results from an abnormal deposition and storage of mucopolysaccharides
alder-reilly anomaly
give two associated disease of alder-reilly anomaly
skeletal dystrophy
gargoylism
wbc anomaly that are rare and autosomal dominant
may-hegglin anomaly
what type of wbc anomaly have a multiple large vacuoles in all granulocytes and monocytes?
jordan anomaly
what is the content of the Dohle bodies?
rRNA
what is the defect part of the czediak-higashi’s wbc that is responsible for granule assembly?
golgi complex
in this anomaly, large hypogranular platelets are seen
may-hegglin anomaly
PAS REACTION
May-hegglin anomaly?
Dohle bodies?
(-) ; (+)
What is the content of may-hegglin anomaly?
mRNA
give two associated conditions of jordan anomaly
Progressive muscular dystrophy
ichthyosis
what are the 6 species affected by th czediak-higashi syndrome?
man mink cattle mine cats killer whales
Wbc anomaly which stain positively in fat?
Jordan anomaly
vacuoles seen in Jordan anomaly are not found in what type of WBC?
lymphocytes
_______ are rod-like bodies which stain reddish-purple in the cytoplasm of myeloblasts in ________.
auer bodies
acute myelocytic leukemia
A rare condition in which both random and directed movement of the cells are defective
lazy leukocyte syndrome
russell bodies appear as ______ structure
grape-like
accumulation of ganglioside and glycolipid
tay-sachs disease
tay - sachs disease is deficient in ______
hexosaminidase type A
bone marrow macrophages filled with foamy cytoplasm because of lipid field lysosomes or soap suds appearance
niemann-pick disease
tay sachs disease is characterized by ______ cytoplasm
vacuolated
bodies with glycophorin component found in Dysproteinemias
dutcher bodies
when you have a gaucher bodies there is an accumulation of ____?
glucocerebroside
gaucher bodies lack what type of enzyme?
beta-glucosidasenor glucocerebroside
cytoplasm that has a wrinkled or onion skin like appearance
gaucher bodies
results from the proteinaceous material produced by immunoglobulins
russell bodies
