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A. HEMA111 > WBC Anomaly > Flashcards

WBC Anomaly Flashcards

1
Q

WBC anomaly seen in severe infections, chemical poisonings and leukemia

clue: marami itong butas 😂

A

vacuolated neutrophil

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2
Q

Hairy cell leukemias are usually seenin patients with _____.

A

Cancer

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3
Q

WBC Anomaly that is usually found in Megaloblastic Anemia

a. Czediak- higashi syndrome
b. vacuolated wbc
c. hypersegmented neutrophil

A

C. hypersegmented neutrophil

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4
Q

Hypersegmented neutrophil has _____ lobes

A

5-10 lobes

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5
Q

WBC anomaly due to rupture of wbc with bare nucleus

A

Smudge cells

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6
Q

What type of wbc anomaly wherein the appearance of the inclusions is transient only?

A

Dohle bodies

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7
Q

What is the most affected organ in LE cell anomaly?

A

Kidney

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8
Q

LE cell is classified as ________ disease.

A

Autoimmune

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9
Q

What type of phagocytic wbc is found in LE cell?

A

Neutrophil

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10
Q

Type of wbc anomaly seen in DRUG SENSITIVITY

A

Tart cells

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11
Q

This wbc anomaly is often associated with scarlet fever

A

Dohle bodies

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12
Q

Prescence of holes or vacuoles in the cytoplasm is a sign of _______ and it is usually found in ________.

A

degeneration; vacuolated wbc

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13
Q

Type of wbc anomaly wherein lymphocytes have notched, lobulated or segmented or clover leaf like nucleus

Clue: Katunog ng taong nakasakay sa english 😂

A

Reider cells

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14
Q

type of wbc anomaly characterized by the failure of the nucleus of neutrophil to segment or lobulate

clue: eyeglasses appearance

A

Pelger huet anomaly

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15
Q

Give two associated disease of Reider cell

A

Chronic lymphocytic or lymphatic leukemia

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16
Q

WBC anomaly that are periodic acid schiff (pas) positive

A

Dohle bodies

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17
Q

Vacuolated wbc may be found in normal blood smear if the smear is made from _________ which is over ____ hrs. old

A

oxalated blood; 2 hrs

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18
Q

A phagocytic wbc that has ingested an altered, homogenous globular nuclear mass of a destroyed cell

A

Lupus erythematosus cell

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19
Q

Wbc anomaly associated with Malignant myeloproliferative neoplasm

A

true pelger huet anomaly

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20
Q

Wbc anomaly consists of rRNA usually in the periphery of cells

clue: department of labor and employee mehehehe

A

Dohle bodies

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21
Q

Dohle bodies may also be found within ______ nuclues.

A

BAND

22
Q

WBC anomaly that reflect sudden storage pool disease

A

Dohle bodies

23
Q

What type of wbc anomaly wherein dohle bodies may also be seen?

A

May-hegglin anomaly

24
Q

type of WBC anomaly characterized by giant cytoplasmic granules in the phagocytes and lymphocytes

A

czediak-higashi syndrome

25
Q

what is the color of toxic granulations?

A

dark blue – black

26
Q

WBC anomaly characterized by dense azurophilic granulations in all types of leukocytes

A

alder-reilly anomaly

27
Q

type of WBC anomaly where in granulations usually results from an abnormal deposition and storage of mucopolysaccharides

A

alder-reilly anomaly

27
Q

give two associated disease of alder-reilly anomaly

A

skeletal dystrophy

gargoylism

28
Q

wbc anomaly that are rare and autosomal dominant

A

may-hegglin anomaly

29
Q

what type of wbc anomaly have a multiple large vacuoles in all granulocytes and monocytes?

A

jordan anomaly

30
Q

what is the content of the Dohle bodies?

A

rRNA

31
Q

what is the defect part of the czediak-higashi’s wbc that is responsible for granule assembly?

A

golgi complex

33
Q

in this anomaly, large hypogranular platelets are seen

A

may-hegglin anomaly

34
Q

PAS REACTION

May-hegglin anomaly?
Dohle bodies?

A

(-) ; (+)

34
Q

What is the content of may-hegglin anomaly?

A

mRNA

35
Q

give two associated conditions of jordan anomaly

A

Progressive muscular dystrophy

ichthyosis

36
Q

what are the 6 species affected by th czediak-higashi syndrome?

A 
man
mink
cattle
mine
cats
killer whales
38
Q

Wbc anomaly which stain positively in fat?

A

Jordan anomaly

38
Q

vacuoles seen in Jordan anomaly are not found in what type of WBC?

A

lymphocytes

39
Q

_______ are rod-like bodies which stain reddish-purple in the cytoplasm of myeloblasts in ________.

A

auer bodies

acute myelocytic leukemia

40
Q

A rare condition in which both random and directed movement of the cells are defective

A

lazy leukocyte syndrome

41
Q

russell bodies appear as ______ structure

A

grape-like

42
Q

accumulation of ganglioside and glycolipid

A

tay-sachs disease

44
Q

tay - sachs disease is deficient in ______

A

hexosaminidase type A

45
Q

bone marrow macrophages filled with foamy cytoplasm because of lipid field lysosomes or soap suds appearance

A

niemann-pick disease

47
Q

tay sachs disease is characterized by ______ cytoplasm

A

vacuolated

49
Q

bodies with glycophorin component found in Dysproteinemias

A

dutcher bodies

51
Q

when you have a gaucher bodies there is an accumulation of ____?

A

glucocerebroside

53
Q

gaucher bodies lack what type of enzyme?

A

beta-glucosidasenor glucocerebroside

55
Q

cytoplasm that has a wrinkled or onion skin like appearance

A

gaucher bodies

58
Q

results from the proteinaceous material produced by immunoglobulins

A

russell bodies

A. HEMA111 (4 decks)

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