WBC Anomaly Flashcards

(51 cards)

1
Q

WBC anomaly seen in severe infections, chemical poisonings and leukemia

clue: marami itong butas 😂

A

vacuolated neutrophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hairy cell leukemias are usually seenin patients with _____.

A

Cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

WBC Anomaly that is usually found in Megaloblastic Anemia

a. Czediak- higashi syndrome
b. vacuolated wbc
c. hypersegmented neutrophil

A

C. hypersegmented neutrophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypersegmented neutrophil has _____ lobes

A

5-10 lobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

WBC anomaly due to rupture of wbc with bare nucleus

A

Smudge cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of wbc anomaly wherein the appearance of the inclusions is transient only?

A

Dohle bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the most affected organ in LE cell anomaly?

A

Kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

LE cell is classified as ________ disease.

A

Autoimmune

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What type of phagocytic wbc is found in LE cell?

A

Neutrophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Type of wbc anomaly seen in DRUG SENSITIVITY

A

Tart cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

This wbc anomaly is often associated with scarlet fever

A

Dohle bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Prescence of holes or vacuoles in the cytoplasm is a sign of _______ and it is usually found in ________.

A

degeneration; vacuolated wbc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Type of wbc anomaly wherein lymphocytes have notched, lobulated or segmented or clover leaf like nucleus

Clue: Katunog ng taong nakasakay sa english 😂

A

Reider cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

type of wbc anomaly characterized by the failure of the nucleus of neutrophil to segment or lobulate

clue: eyeglasses appearance

A

Pelger huet anomaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Give two associated disease of Reider cell

A

Chronic lymphocytic or lymphatic leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

WBC anomaly that are periodic acid schiff (pas) positive

A

Dohle bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Vacuolated wbc may be found in normal blood smear if the smear is made from _________ which is over ____ hrs. old

A

oxalated blood; 2 hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A phagocytic wbc that has ingested an altered, homogenous globular nuclear mass of a destroyed cell

A

Lupus erythematosus cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Wbc anomaly associated with Malignant myeloproliferative neoplasm

A

true pelger huet anomaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Wbc anomaly consists of rRNA usually in the periphery of cells

clue: department of labor and employee mehehehe

A

Dohle bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Dohle bodies may also be found within ______ nuclues.

22
Q

WBC anomaly that reflect sudden storage pool disease

23
Q

What type of wbc anomaly wherein dohle bodies may also be seen?

A

May-hegglin anomaly

24
Q

type of WBC anomaly characterized by giant cytoplasmic granules in the phagocytes and lymphocytes

A

czediak-higashi syndrome

25
what is the color of toxic granulations?
dark blue – black
26
WBC anomaly characterized by dense azurophilic granulations in all types of leukocytes
alder-reilly anomaly
27
type of WBC anomaly where in granulations usually results from an abnormal deposition and storage of mucopolysaccharides
alder-reilly anomaly
27
give two associated disease of alder-reilly anomaly
skeletal dystrophy | gargoylism
28
wbc anomaly that are rare and autosomal dominant
may-hegglin anomaly
29
what type of wbc anomaly have a multiple large vacuoles in all granulocytes and monocytes?
jordan anomaly
30
what is the content of the Dohle bodies?
rRNA
31
what is the defect part of the czediak-higashi's wbc that is responsible for granule assembly?
golgi complex
33
in this anomaly, large hypogranular platelets are seen
may-hegglin anomaly
34
PAS REACTION May-hegglin anomaly? Dohle bodies?
(-) ; (+)
34
What is the content of may-hegglin anomaly?
mRNA
35
give two associated conditions of jordan anomaly
Progressive muscular dystrophy | ichthyosis
36
what are the 6 species affected by th czediak-higashi syndrome?
``` man mink cattle mine cats killer whales ```
38
Wbc anomaly which stain positively in fat?
Jordan anomaly
38
vacuoles seen in Jordan anomaly are not found in what type of WBC?
lymphocytes
39
_______ are rod-like bodies which stain reddish-purple in the cytoplasm of myeloblasts in ________.
auer bodies | acute myelocytic leukemia
40
A rare condition in which both random and directed movement of the cells are defective
lazy leukocyte syndrome
41
russell bodies appear as ______ structure
grape-like
42
accumulation of ganglioside and glycolipid
tay-sachs disease
44
tay - sachs disease is deficient in ______
hexosaminidase type A
45
bone marrow macrophages filled with foamy cytoplasm because of lipid field lysosomes or soap suds appearance
niemann-pick disease
47
tay sachs disease is characterized by ______ cytoplasm
vacuolated
49
bodies with glycophorin component found in Dysproteinemias
dutcher bodies
51
when you have a gaucher bodies there is an accumulation of ____?
glucocerebroside
53
gaucher bodies lack what type of enzyme?
beta-glucosidasenor glucocerebroside
55
cytoplasm that has a wrinkled or onion skin like appearance
gaucher bodies
58
results from the proteinaceous material produced by immunoglobulins
russell bodies