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HEMA (JUANILLO) > WBC > Flashcards

WBC Flashcards

1
Q

larger then rbc, nucleated

A

leukocyte

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2
Q

malignant proliferation of wbc producing cells

A

leukemia

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3
Q

increase wbc

A

leukocytosis

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4
Q

decrease wbc

A

leukopenia

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5
Q

turnover time of labeled compartment

A

grain count halving time

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5
Q

principle: difference in size and density allow the separation of formed elements

A

leukocyte fractionation

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5
Q

formation of life span of neutrophil

A

9-10 days from myeloblast to death

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6
Q

separates particles in similar density

A

zonal sedimentation

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6
Q

separates particles in similar sizes

A

zonal centrifugation

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7
Q

not capable of mitosis

A

metamyelocyte

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8
Q

undergo cell division

A

myeloblast, promyelocyte and myelocyte

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9
Q

contains about 15 times band and segmenters

A

storage pool> peripheral blood

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10
Q

insinuate themselves through the walls of capillaries bet. endothelial cell

A

diapedesis

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11
Q

neutrophils, distinct asymmetric shape

A

hand mirror

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12
Q

glass mirror formed by pseudopod and called

A

lamellopod

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13
Q

one of the two x chromosomes in the cell of a female become in active, what process?

A

lyon hypothesis

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14
Q

expressed in neutrophil used to detect hidden infection

A

cd15

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15
Q

condensation of chromatin below nuclear membrane

A

barr body

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16
Q

avidity binds to neutrophil

A

wistar antibody

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17
Q

neutrophils containing small and dark gray inclusion

A

ragocytes

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18
Q

ability of neutrophil to sense presence of particulate

A

chemotaxis or leukotaxis

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19
Q

undefined neutrophil defect
reduced adhesion and migration

A

lazy leukocyte syndorme

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20
Q

-random movement is normal and directional
-motility is impaired
-response with boils

A

job syndrome

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21
Q

glycoprotein found in plasma and outer membrane fibrolast

A

fibronectin

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22
-opsonins are components of fresh serum that coat foreign particle -act upon bacteria to make them tasty
opsonization
23
fusion of phagocytic vacuole with lysosome
degranulATION
24
failure of granule release
chediak higashi
25
inability to ingest organism
congenital c3 deficiency
26
chronic granulomatous disease
defect in oxidative metabolism
27
impairs hms, unable to produce respiratory burst
g6pd
28
absent only in neutrophil and monocyte normal in eosinophil severe candida infection
myeloperoxidase ediciency
29
cyclic neutropenia recurring within cycle of
19-21 days
30
derived from single precursor cell with all the affected cell (progeny)
clonal disorder
31
stable protein that serves marker for leukocyte
lactoferrin
32
knapsack shaped nucelus
eosinophil
33
eosiniphil can be found in tissues such as
skin other epithelial barriers intestinal tract lungs "SOIL"
34
eosinophil spend ___ in circulation , ___ in production
8 hrs, 3-6 days
35
excellent stain to demonstrate eosinophil in eosinophiluria
hansel secretion stain
36
charcot-leyden crystals composed of
lysophospholipase
37
allergic angitis an granulomatosis
churg-strauss syndrome
38
basophils matures in
7 days
39
sluggish locomotion and phagocytosis
basophil
40
produced by t-lymphocyte for recruitment from circulation to sites of allergic reaction
basophilopoietin
41
cytochemical reaction can be used to identify basophils
epsilon-aminocaproate
42
monocyte enters circulation for
18 hrs
43
monocyte remains in the blood fro approx.
3 days
44
involve in nursing or suckling phenomenon
monocyte
45
___ receptor on macrophage binds ___ and aid in adhesion
CR 1 , C3 b
46
monocytic leukocytosis infection bacterial : tb secretes __
dihydrolipoamide acyl transferase
47
promotes maturation of t-lymphocyte
thymosin
48
pre-thymocyte and thymocyte process TdT
terminal deoxynucleotidyl transferase
49
t-lymphocyte develops in
thymus
50
t lymphocyte develops surface antigen
theta antigen
51
lymphocyte that remains programmed
memory cells
52
program a population of b-lymphocyte
helper cells
53
cooperates GVH reactive t cells
Th (amplifier cells)
54
limit the immunologic activity of other lymphocyte
suppressor cells
55
respond to particulate and soluble antigens by producing chemotactic lymphokines
Delayed Hypersensitivity T-lymphocyte
56
regulate suppressor and helper t cells
activator cells
57
blocks the reproduction of viruses
interferon
58
secreted by leukocytes upon exposure
alpha interferon
58
secreted by fibroblasts
beta interferon
59
secreted by lymphoid cells
gama interferon
60
kills targets cells, and foreign substances and causes tissue damage
lymphokines
61
directs movement of macrophage, monocyte and granulocyte
chemotactic factor
62
defective development of lymphoid thymus
Nezelof syndrome
63
not a genetic origin but may result from intrauterine infection
Di george syndrome
64
infantile sex linked agamma
brutons agammaglobulinemia
65
other name for B lys S
TALL 1
66
loss both t and b function
swiss type agammaglobulinemia
67
failure to generate adequate t cell response
wiskott aldrich
68
ataxia telaengiectasia
dilation of small blood vesssels
69
immunosurveillance against tumor cells
natural killer cell
70
lymphocytotoxicity test measuring the degree of antibody reactivity
PRA percent reactive antibody
71
plasma cell labeling index
2 bromo 2 deoxyuridine
72
to detect dohle bodies non cytochemical satin
pappenheim methyl green pyronine stain
73
to detect true reticulum fibers and stroma cells
gomori silver-gold impregnation
74
used to rule in ALL
PAS and ORO
75
used to rule in granulocytic leukemia
SBB, MP, D-CI-E
76
used to distinguish CML from other leukocutosis
NAP
77
rule in hairy cell leukemia
ACP
78
absolute basophil count
to distinguish between progranuclocyte and basophils
79
toluidine blue method
copper & cruickshank method
80
lyse erythrocyte and render basophilic granules
cetylpyrimidium chloride
81
used as mordant
aluminum sulfate
82
associated with gargoylism
alder-reilly anomaly
83
rodlike structure in cytoplasm of monoblast and myeloblast
aur bodies
84
irregularly size inclusion bodies, cerulean blue areas in cytoplasm of PMN
Dohle-Amato bodies
85
prsence of fat containing vacuoles
jordan anomaly
86
presence of inclusion in pmn and monocyte
may-hegglin anomaly
87
failure of nucleus of neutrophil to lobulate
pelger-huet
88
degenerating or ruptured wbc
smudge/basket cell
89
due to erlichiosis infections
basophilic morule body
90
sex-linked recssive (disease of male infants)
Chronic granulomatous Disease
91
lymphocyte with thread like projection
hairy cells
92
maturation off nautrophil causing macropolycytes
undritz anomaly
93
generally specific for SLE
Anti Native DNA and anto- Sm
94
SnRNP
containd uracil
95

HEMA (JUANILLO) (3 decks)

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