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HEMA (JUANILLO) > WBC > Flashcards

WBC Flashcards

1
Q

larger then rbc, nucleated

A

leukocyte

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2
Q

malignant proliferation of wbc producing cells

A

leukemia

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3
Q

increase wbc

A

leukocytosis

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4
Q

decrease wbc

A

leukopenia

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5
Q

turnover time of labeled compartment

A

grain count halving time

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5
Q

principle: difference in size and density allow the separation of formed elements

A

leukocyte fractionation

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5
Q

formation of life span of neutrophil

A

9-10 days from myeloblast to death

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6
Q

separates particles in similar density

A

zonal sedimentation

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6
Q

separates particles in similar sizes

A

zonal centrifugation

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7
Q

not capable of mitosis

A

metamyelocyte

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8
Q

undergo cell division

A

myeloblast, promyelocyte and myelocyte

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9
Q

contains about 15 times band and segmenters

A

storage pool> peripheral blood

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10
Q

insinuate themselves through the walls of capillaries bet. endothelial cell

A

diapedesis

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11
Q

neutrophils, distinct asymmetric shape

A

hand mirror

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12
Q

glass mirror formed by pseudopod and called

A

lamellopod

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13
Q

one of the two x chromosomes in the cell of a female become in active, what process?

A

lyon hypothesis

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14
Q

expressed in neutrophil used to detect hidden infection

A

cd15

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15
Q

condensation of chromatin below nuclear membrane

A

barr body

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16
Q

avidity binds to neutrophil

A

wistar antibody

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17
Q

neutrophils containing small and dark gray inclusion

A

ragocytes

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18
Q

ability of neutrophil to sense presence of particulate

A

chemotaxis or leukotaxis

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19
Q

undefined neutrophil defect
reduced adhesion and migration

A

lazy leukocyte syndorme

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20
Q

-random movement is normal and directional
-motility is impaired
-response with boils

A

job syndrome

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21
Q

glycoprotein found in plasma and outer membrane fibrolast

A

fibronectin

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22
Q

-opsonins are components of fresh serum that coat foreign particle
-act upon bacteria to make them tasty

A

opsonization

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23
Q

fusion of phagocytic vacuole with lysosome

A

degranulATION

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24
Q

failure of granule release

A

chediak higashi

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25
Q

inability to ingest organism

A

congenital c3 deficiency

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26
Q

chronic granulomatous disease

A

defect in oxidative metabolism

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27
Q

impairs hms, unable to produce respiratory burst

A

g6pd

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28
Q

absent only in neutrophil and monocyte
normal in eosinophil
severe candida infection

A

myeloperoxidase ediciency

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29
Q

cyclic neutropenia recurring within cycle of

A

19-21 days

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30
Q

derived from single precursor cell with all the affected cell (progeny)

A

clonal disorder

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31
Q

stable protein that serves marker for leukocyte

A

lactoferrin

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32
Q

knapsack shaped nucelus

A

eosinophil

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33
Q

eosiniphil can be found in tissues such as

A

skin
other epithelial barriers
intestinal tract
lungs

“SOIL”

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34
Q

eosinophil spend ___ in circulation , ___ in production

A

8 hrs, 3-6 days

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35
Q

excellent stain to demonstrate eosinophil in eosinophiluria

A

hansel secretion stain

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36
Q

charcot-leyden crystals composed of

A

lysophospholipase

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37
Q

allergic angitis an granulomatosis

A

churg-strauss syndrome

38
Q

basophils matures in

A

7 days

39
Q

sluggish locomotion and phagocytosis

A

basophil

40
Q

produced by t-lymphocyte for recruitment from circulation to sites of allergic reaction

A

basophilopoietin

41
Q

cytochemical reaction can be used to identify basophils

A

epsilon-aminocaproate

42
Q

monocyte enters circulation for

A

18 hrs

43
Q

monocyte remains in the blood fro approx.

A

3 days

44
Q

involve in nursing or suckling phenomenon

A

monocyte

45
Q

___ receptor on macrophage binds ___ and aid in adhesion

A

CR 1 , C3 b

46
Q

monocytic leukocytosis infection bacterial : tb secretes __

A

dihydrolipoamide acyl transferase

47
Q

promotes maturation of t-lymphocyte

A

thymosin

48
Q

pre-thymocyte and thymocyte process TdT

A

terminal deoxynucleotidyl transferase

49
Q

t-lymphocyte develops in

A

thymus

50
Q

t lymphocyte develops surface antigen

A

theta antigen

51
Q

lymphocyte that remains programmed

A

memory cells

52
Q

program a population of b-lymphocyte

A

helper cells

53
Q

cooperates GVH reactive t cells

A

Th (amplifier cells)

54
Q

limit the immunologic activity of other lymphocyte

A

suppressor cells

55
Q

respond to particulate and soluble antigens by producing chemotactic lymphokines

A

Delayed Hypersensitivity T-lymphocyte

56
Q

regulate suppressor and helper t cells

A

activator cells

57
Q

blocks the reproduction of viruses

A

interferon

58
Q

secreted by leukocytes upon exposure

A

alpha interferon

58
Q

secreted by fibroblasts

A

beta interferon

59
Q

secreted by lymphoid cells

A

gama interferon

60
Q

kills targets cells, and foreign substances and causes tissue damage

A

lymphokines

61
Q

directs movement of macrophage, monocyte and granulocyte

A

chemotactic factor

62
Q

defective development of lymphoid thymus

A

Nezelof syndrome

63
Q

not a genetic origin but may result from intrauterine infection

A

Di george syndrome

64
Q

infantile sex linked agamma

A

brutons agammaglobulinemia

65
Q

other name for B lys S

A

TALL 1

66
Q

loss both t and b function

A

swiss type agammaglobulinemia

67
Q

failure to generate adequate t cell response

A

wiskott aldrich

68
Q

ataxia telaengiectasia

A

dilation of small blood vesssels

69
Q

immunosurveillance against tumor cells

A

natural killer cell

70
Q

lymphocytotoxicity test measuring the degree of antibody reactivity

A

PRA percent reactive antibody

71
Q

plasma cell labeling index

A

2 bromo 2 deoxyuridine

72
Q

to detect dohle bodies
non cytochemical satin

A

pappenheim methyl green pyronine stain

73
Q

to detect true reticulum fibers and stroma cells

A

gomori silver-gold impregnation

74
Q

used to rule in ALL

A

PAS and ORO

75
Q

used to rule in granulocytic leukemia

A

SBB, MP, D-CI-E

76
Q

used to distinguish CML from other leukocutosis

A

NAP

77
Q

rule in hairy cell leukemia

A

ACP

78
Q

absolute basophil count

A

to distinguish between progranuclocyte and basophils

79
Q

toluidine blue method

A

copper & cruickshank method

80
Q

lyse erythrocyte and render basophilic granules

A

cetylpyrimidium chloride

81
Q

used as mordant

A

aluminum sulfate

82
Q

associated with gargoylism

A

alder-reilly anomaly

83
Q

rodlike structure in cytoplasm of monoblast and myeloblast

A

aur bodies

84
Q

irregularly size inclusion bodies, cerulean blue areas in cytoplasm of PMN

A

Dohle-Amato bodies

85
Q

prsence of fat containing vacuoles

A

jordan anomaly

86
Q

presence of inclusion in pmn and monocyte

A

may-hegglin anomaly

87
Q

failure of nucleus of neutrophil to lobulate

A

pelger-huet

88
Q

degenerating or ruptured wbc

A

smudge/basket cell

89
Q

due to erlichiosis infections

A

basophilic morule body

90
Q

sex-linked recssive (disease of male infants)

A

Chronic granulomatous Disease

91
Q

lymphocyte with thread like projection

A

hairy cells

92
Q

maturation off nautrophil causing macropolycytes

A

undritz anomaly

93
Q

generally specific for SLE

A

Anti Native DNA and anto- Sm

94
Q

SnRNP

A

containd uracil

95
Q
A

HEMA (JUANILLO) (3 decks)

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