Water soluble vitamins

Question 1

True or false; Vit C functions in non-heme iron absorption

Answer 1

true

Question 2

What step of collagen synthesis does Vit C participate in

Answer 2

hydroxylation step

Question 3

True or false; peppers are good sources of Vit C

Answer 3

true

Question 4

What are the 4 H’s of scurvy

Answer 4

Hemorrhagic
Hematologic
Hyper-keratosis
Hyper-chondrosis

Question 5

Toxicity of Vit C causes what?

Answer 5

diarrhea

Question 6

TDP is coenzyme formed from which vitamin

Answer 6

Thiamin (B1)

Question 7

TDP the coenzyme made from thiamine (B1) is used in what?

Answer 7

pyruvate to Acetyl-CoA

Question 8

What is TTP (non-coenzyme) made from thiamine (B1) is used in what? Which is important in…

Answer 8

Na+/Cl- transport

important in nervous system (nerve transduction)

Question 9

Wet beri beri effects who? causes..

Answer 9

Adults - causes enlarged heart

Thiamine (B1) deficiency

Question 10

Dry beri beri effects who? causes..

Answer 10

Geriatrics - causes peripheral neuropathy

Thiamine (B1) deficiency

Question 11

Acute beri beri effects who? causes…

Answer 11

Babies - causes heart enlargement

Thiamine (B1) deficiency

Question 12

True or false; beri beri causes tender calf muscles

Answer 12

true
Thiamine (B1) deficiency

Question 13

What is beri beri?

Answer 13

Thiamine (B1) deficiency

Question 14

What is the function of riboflavin (B2)

Answer 14

FAD and FMN (coenzymes) dehydrogenases

Question 15

Which step of OHOT is riboflavin (B2) associated with?

Answer 15

1st step

Question 16

True or false; FAD and FMN (products of riboflavin B2) are used in the synthesis of niacin (B3) and B6

Answer 16

true

Question 17

What are some sources of B2 (riboflavin)

Answer 17

dark green leafy veggies
Dairy
Whole grains

Question 18

Ariboflavinosis (deficiency of B2) is associated with cheilosis and angular stomatitis

Answer 18

true

Question 19

Magenta tongue is associated with what deficiency

Answer 19

B2 (riboflavin)

Question 20

“Burning feet syndrome” is associated with what deficiency

Answer 20

B5 (pantothenic acid)

Question 21

What function does pantothenic acid (B5) play a role in?

Answer 21

CoA production for krebs and OHOT

Acyl carrier protein for lipid synthesis

Question 22

What are some sources of pantothenic acid B5?

Answer 22

meat, animal products and whole grains/legumes

Question 23

What is biotin (B7) bound to?

Answer 23

carboxylase

Question 24

What are some sources of biotin (B7)

Answer 24

dairy
nuts
large intestine bacteria

Question 25

What is unique about biotin (B7) and raw eggs

Answer 25

if consuming raw eggs - contain a chelator that binds biotin preventing absorption of B7

Question 26

What population is most likely to be deficient in biotin (B7)

Answer 26

pregnant women

Question 27

What are some symptoms of biotin (B7) deficiency

Answer 27

dermatitis glossitis increased cholesterol (LDL levels)

Question 28

What is niacin (B3) made from

Answer 28

tryptophan

Question 29

NAD (dehydrogenase) made from Niacin (B3) is used in which step of OHOT

Answer 29

2nd step

Question 30

NADPH made from Niacin (B3) is used in the synthesis of what?

Answer 30

F.A.'s & cholesterol | Triglycerides

Question 31

What is the main source of niacin (B3)

Answer 31

meat

Question 32

Deficiency of Niacin (B3) is called what?

Answer 32

Pellagra

Question 33

What are the 4 D's of pellagra (Niacin B3 deficiency)

Answer 33

Dermatitis Dementia Diarrhea Death

Question 34

Pyridoxine B6 is used in the synthesis of what?

Answer 34

neurotransmitters Myelin sheath Heme

Question 35

What are some sources of B6 (pyridoxine)

Answer 35

Meat (main source) | whole grains

Question 36

What are some symptoms of B6 (pyridoxine) deficiency

Answer 36

fatigue | peripheral neuropathy

Question 37

True or false; Cobalamin (B12) functions in A.A. metabolism

Answer 37

true (adenosylcobalamin)

Question 38

What is methylcobalamin (B12) used in?

Answer 38

Methylation and removal of homocysteine (increased homocysteine is correlated with increased risk of CVD)

Question 39

True or false; meat, fish and dairy are all sources of B12 (cobalamin)

Answer 39

true

Question 40

Megaloblastic anemia and pernicous anemia are both consequences of deficiency of what vitamin

Answer 40

Cobalamin (B12)

Question 41

What binds cobalamin (B12) in stomach?

Answer 41

R-protein

Question 42

What binds cobalamin (B12) in SI

Answer 42

intrinsic factor (from parietal cells of stomach)

Question 43

Patients with Zogeler Ellison syndrome have impaired absorption of Cobalamin (B12) in the SI because...

Answer 43

increased HCl secretion which denatures intrinsic factor

Question 44

True or false; patients taking reflux medications can have impaired absorption of Cobalamin (B12) in the SI

Answer 44

true

Question 45

How is Cobalamin (B12) absorbed?

Answer 45

Receptor mediated endocytosis

Question 46

Where is Cobalamin (B12) stored?

Answer 46

Liver

Question 47

What are some sources of Folate (B9)

Answer 47

dark green leafy veggies legumes (needs Zinc for absorption)

Question 48

What mineral does Folate (B9) need for absorption

Answer 48

Zinc

Question 49

What function does Folate (B9) play a role in the body?

Answer 49

THF used for Methylation (used in DNA, Erythropoesis production and leukocyte production)

Question 50

What two water soluble vitamins are used in methylation

Answer 50

Cobalamin (B12) and Folate (B9)

Question 51

Folic acid (B9) which is important for developing embryos can be found where

Answer 51

supplements and fortified cereals

Question 52

Megaloblastic anemia and nerual tube defects are both caused by a deficiency in this vitamin

Answer 52

Folate (B9)

Question 53

True or false; Tryptophan (used in Niacin B3 production) is found readily in meats (protein sources)

Answer 53

true

Question 54

One of Vitamin C's functions is in Non-heme iron absorption what is non-heme iron?

Answer 54

the iron found in supplements or plants

Question 55

True or false; if you have too much folic acid you decrease your zinc absorption (which is required for folate B9 absorption)

Answer 55

true