Water Reabsoprtion In Intestine Flashcards
How much loss of fluid is there with diarrhoea?
Loss of fluid and solutes form the GI tract in excess of 500ml per day
Where does Na+/glucose get reabsorbed
Small intestine
Where does Na+/amino acid get reabsorbed?
Small intestine
Where does Na+/H+ exchange reabsorption occur?
Duodenum and jejunum
Where does parallel Na+/H+ and Cl-/HCO3- exchange reabsorption occur?
Ileum and colon
Where are the epithelial Na+ channel located?
Distal colon
Where does Cl- absorption occur?
Passively via trans cellular and paracellular routes in the small intestine
What are the driving forces provided by in the small and large intestine
Electro genie movement of Na+
Which cells does Cl- secretion occur at?
Crypt cells
Which process are involved on the absolute real membrane?
Na+/K+ ATPase
Na+/K+/2cl - co transporter (NKCC1)
K+ channels
What occurs at the bass lateral membrane?
Low intracellular Na+ drives inward movement of Na+, K+ and Cl- via NKCC1
K+ recycles
Cl- intracellular conc increases = electrochemical gradient for Cl- to exit CFTR membrane
Lumen negative potential develops providing voltage dependent secretion of Na+ through paracellular pathway
Which mechanism reabsorbed Cl-
Na+/glucose co transport
Na+/ amino acid co transport