Water Reabsoprtion In Intestine

Question 1

How much loss of fluid is there with diarrhoea?

Answer 1

Loss of fluid and solutes form the GI tract in excess of 500ml per day

Question 2

Where does Na+/glucose get reabsorbed

Answer 2

Small intestine

Question 3

Where does Na+/amino acid get reabsorbed?

Answer 3

Small intestine

Question 4

Where does Na+/H+ exchange reabsorption occur?

Answer 4

Duodenum and jejunum

Question 5

Where does parallel Na+/H+ and Cl-/HCO3- exchange reabsorption occur?

Answer 5

Ileum and colon

Question 6

Where are the epithelial Na+ channel located?

Answer 6

Distal colon

Question 7

Where does Cl- absorption occur?

Answer 7

Passively via trans cellular and paracellular routes in the small intestine

Question 8

What are the driving forces provided by in the small and large intestine

Answer 8

Electro genie movement of Na+

Question 9

Which cells does Cl- secretion occur at?

Answer 9

Crypt cells

Question 10

Which process are involved on the absolute real membrane?

Answer 10

Na+/K+ ATPase
Na+/K+/2cl - co transporter (NKCC1)
K+ channels

Question 11

What occurs at the bass lateral membrane?

Answer 11

Low intracellular Na+ drives inward movement of Na+, K+ and Cl- via NKCC1
K+ recycles
Cl- intracellular conc increases = electrochemical gradient for Cl- to exit CFTR membrane
Lumen negative potential develops providing voltage dependent secretion of Na+ through paracellular pathway

Question 12

Which mechanism reabsorbed Cl-

Answer 12

Na+/glucose co transport

Na+/ amino acid co transport