Water Reabsoprtion In Intestine Flashcards

1
Q

How much loss of fluid is there with diarrhoea?

A

Loss of fluid and solutes form the GI tract in excess of 500ml per day

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2
Q

Where does Na+/glucose get reabsorbed

A

Small intestine

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3
Q

Where does Na+/amino acid get reabsorbed?

A

Small intestine

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4
Q

Where does Na+/H+ exchange reabsorption occur?

A

Duodenum and jejunum

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5
Q

Where does parallel Na+/H+ and Cl-/HCO3- exchange reabsorption occur?

A

Ileum and colon

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6
Q

Where are the epithelial Na+ channel located?

A

Distal colon

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7
Q

Where does Cl- absorption occur?

A

Passively via trans cellular and paracellular routes in the small intestine

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8
Q

What are the driving forces provided by in the small and large intestine

A

Electro genie movement of Na+

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9
Q

Which cells does Cl- secretion occur at?

A

Crypt cells

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10
Q

Which process are involved on the absolute real membrane?

A

Na+/K+ ATPase
Na+/K+/2cl - co transporter (NKCC1)
K+ channels

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11
Q

What occurs at the bass lateral membrane?

A

Low intracellular Na+ drives inward movement of Na+, K+ and Cl- via NKCC1
K+ recycles
Cl- intracellular conc increases = electrochemical gradient for Cl- to exit CFTR membrane
Lumen negative potential develops providing voltage dependent secretion of Na+ through paracellular pathway

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12
Q

Which mechanism reabsorbed Cl-

A

Na+/glucose co transport

Na+/ amino acid co transport

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