Water Balance Flashcards
Osmolyte
Solutes that change the colligative properties of water
Plasmolysis
Shrinking of the cell
Insensible water loss
Losses in exhaled air, through the skin or in feces
Overhydration
greater than normal fluid volume
Causes of hypertonic dehydration
- Respiration
- Sweat (humans)
- Inappropriate production of hypotonic urine
Osmolarity
Concentration of osmolyte
Two types of edema
Generalized
Localized
Concentration (C) = __________.
Concentration (C) = Mass / Volume.
Causes of isotonic dehydration
- Hemorrhage
- Sweat
___________: plasma in the animal is hypotonic, because the gain of water exceeds the gain of osmolyte.
Hypotonic Overhydration: plasma in the animal is hypotonic, because the gain of water exceeds the gain of osmolyte.
_____________________
Increased water, no change in osmolyte = cell swell
Important Anions of Plasma and Interstitium
Cl- and HCO3-
Hypotonic
Solution will cause the cell to swell
Net movement of water eventually results in _______________ pressures.
Net movement of water eventually results in equal but opposing pressures.
_________ pressure decreases dramatically from arteriole to venule
CHP pressure decreases dramatically from arteriole to venule
________ of body water is extracellular water.
20% of body water is extracellular water.
Important cations of the intracellular fluid
K+ and Mg2+
Dehydration
Less than normal fluid volume
Normal osmolarity
286-290 mOm
_____ of extracellular water is plasma water.
4% of extracellular water is plasma water.
Crenation
Term used synonymously with plasmolysis as it occurs in red blood cells
_________ are pressures from interstitium to plasma
Reabsorption are pressures from interstitium to plasma
Decreased PCOP caused by
Starvation
Kidney Disease
Liver Disease
_____________________
Decreased [protein] in plasma, thus decreased water moving into the capillary
Causes of hypotonic overhydration
- Psycogenic
- Excess Reabsorption of water
- Drowning
Cardiac output = ____________.
Cardiac output = Stroke Volume x Heart Rate.
__________ of water is critical to normal functioning of the body.
Distribution of water is critical to normal functioning of the body.
Molal = ________.
Molal = Moles / Liter of H2O.
__________: mole of charge; equal + and -.
Equivalent: mole of charge; equal + and -.
_________: effective osmotic pressure; whether the movement of water will cause a cell to change in size
Tonicity: effective osmotic pressure; whether the movement of water will cause a cell to change in size
Starling Forces are
CHP
IFHP
PCOP
IFCOP
___________ are pressures from plasma to interstitium
Filtration are pressures from plasma to interstitium
All biological reactions occur in an _________ environment.
All biological reactions occur in an aqueous environment.
__________: Sum of protons and neutrons.
Mole: Sum of protons and neutrons.
Examples of ___________ include boiling and freezing points.
Examples of colligative properties include boiling and freezing points.
____________ maintains the volume, composition and concentration of solutes in all compartments.
Homeostasis maintains the volume, composition and concentration of solutes in all compartments.
Increased CHP is caused by
Decrease radius of veins
Decreased fluid in venous system
_______________
Increased osmotic pressure into the capillary, thus increased hydrostatic pressure to equalize it
Capillary epithelium is permeable to __________.
Capillary epithelium is permeable to electrolytes.
_________________________
This is why plasma and interstitium have equal [electrolytes]
Most accurate estimate of plasma osmolarity
1.86 [Na+K] + [Glucose/18] + [Urea/3]
There is an increased [_______] in plasma which also increases the ________ pressure.
There is an increased [protein] in plasma which also increases the osmotic pressure.
________ pressure increases and then decreases from arteriole to venule
PCOP pressure increases and then decreases from arteriole to venule
_____________: plasma in the animal is isotonic, because isotonic fluid is lost.
Isotonic Dehydration: plasma in the animal is isotonic, because isotonic fluid is lost.
____________________
Decreased water, Decreased osmolyte
The most valuable nutrient is ________.
The most valuable nutrient is water.
Solutes move from one fluid compartment to another by:
- Endocytosis
- Exocytosis
- Pressure filtration at the glomerulus
- Solvent drag
Least accurate estimate of plasma osmolarity
2 [Na+]
Plasma is separated from interstitial fluid by ____________.
Plasma is separated from interstitial fluid by capillary epithelium
Cytolysis
Cell swelling to point where stress on plasma membrane causes it to rupture
Important anions of intracellular fluid
HPO4 2- and Protein
Hypervolemia
Greater than normal blood volume
_________: plasma in the animal is isotonic, because isotonic fluid is gained.
Isotonic Overhydration: plasma in the animal is isotonic, because isotonic fluid is gained.
1 kg H2O = ___ L H2O
1 kg H2O = 1 L H2O
Normovolemia
Normal blood volume
Molar = _________.
Molar = Moles / Liter.
Flow = _________ or _______.
Flow = Volume / Time or Mass / (Time x C).
_________ of body weight is water.
60% of body weight is water.
_____________: plasma in the animal is hypertonic because water loss exceeds loss of osmolyte.
Hypertonic Dehydration: plasma in the animal is hypertonic because water loss exceeds loss of osmolyte.
___________________
Decreased water, no change in osmolyte = cell shrinks
Cardiac Output
Flow of blood out of the heart
Hypovolemia
Less than normal blood volume
_______ pressure and _______ pressure are unchanged from arteriole to venule.
IFHP pressure and IFCOP pressure are unchanged from arteriole to venule.
A rough estimate of blood is
1/2 Plasma, 1/2 Cells
Mole = _______.
Mole = 6.02x1023.
Intracellular and extracellular fluids are separated by ______________.
Intracellular and extracellular fluids are separated by cell membrane.
Most of extracellular fluid percentage is made up of ___________.
Most of extracellular fluid percentage is made up of interstitial fluid.
________ predomiates at the arteriole, _______ predominates at the venule.
Filtration predomiates at the arteriole, Reabsorption predominates at the venule.
Sensible water loss
Losses in urine; volume easilty measured
Plasma and Interstitial Fluid are considered to be ______cellular fluid.
Plasma and Interstitial Fluid are considered to be extracellular fluid.
Edema
Collection of abnormally high amounts of interstital fluid
Most common form of dehydration
Hypertonic Dehydration
Causes of isotonic overhydration
- Iatrogenic
- Excess reabsorption of Na
Ventilation
Flow of air into and out of the lungs
Osmole
A mole of osmolyte
________ of body water is intracellular water.
40% of body water is intracellular water.
______ of extracellular water is extracellular fluids.
16% of extracellular water is extracellular fluids.
Ventilation = _________________
Ventilation = Respiratory Rate x Tidal Volume
Increased [solute] will _________ osmotic pressure due to water movement toward the impermeant solute.
Increased [solute] will increase osmotic pressure due to water movement toward the impermeant solute.
Equivalent (Eq) = _________.
Equivalent (Eq) = (g substance) (valence) / Atomic Weight.
Osmotic Pressure
Pressure exerted in a solution with impermeant solute and water crossing barrier
A solution in whihc causes osmosis is referred to as __________.
A solution in whihc causes osmosis is referred to as osmotically active.
Osmosis
Net movement of water from a solution with lesser concentration of impermeant solute to solution of greater concentration of impermeant solute
Imporant cations of Plasma and Interstitium
Na+ and K+
Edema can be caused by
Increased CHP
Decreased PCOP
Increased IFCOP
Isotonic
Solution will cause a cell lto neither shrink or swell
Hypertonic
Solution will cause teh cell to shrink
If an osmolyte cannot cross a membrane which allow the passage of water, ______ will occur.
If an osmolyte cannot cross a membrane which allow the passage of water, osmosis will occur.
___________: plasma in the animal is hypotonic, because los of osmolyte exceeds loss of water.
Hypotonic dehydration: plasma in the animal is hypotonic, because los of osmolyte exceeds loss of water.
_____________________
No change in water, increase of osmolyte
Increased IFCOP caused by
Inflammation
Tissue damage
Inadequate or obstructed lymph flow
________________
Increased interstital proteins causes an increase in water flowing into the interstitium
Solvent drag
Solutes dissolved in water are transported as water moves paracellularly