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D&T3 Exam 2 > Walden4 > Flashcards

Walden4 Flashcards

1
Q

Enteric amebiasis

Transmission

A

Hand-to-mouth transfer of feces

In large intestine, spreads to lungs and liver

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2
Q

Enteric amebiasis

How to differentiate between species

A

PCR

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3
Q

Enteric amebiasis

Who gets it?

A

Think travelers from 3rd world country

Men having sex with men

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4
Q

Enteric amebiasis

Life cycle progression

A

Cyst divide to trophozoites. Trophozoites multiply and produce cysts but can also invade tissue

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5
Q

Enteric amebiasis

Sx

A

Recurrent abdominal cramping and diarrhea

Fever, chills, bloody or mucous diarrhea and weight loss

Small volume diarrhea

Tenesmus (straining and cramping)

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6
Q

Enteric amebiasis

Fever and right upper quadrant pain

A

Liver abscess

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7
Q

Enteric amebiasis

Liver abscesses

A

Don’t occur with bowel symptoms, ameba are found in stool less than 20% of the time

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8
Q

Enteric amebiasis

Amebic pulmonary disease

A

Liver abscess ruptures through diaphragm

Pleuritic pain, RUQ pain, cough, expectoration, SOB

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9
Q

Enteric amebiasis

Diagnosis

A

E. Histolytica, mashkovskii and dispar all look the same!

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10
Q

Enteric amebiasis

Microscopy

A

Stool for O&P (w/in 30 min)

Gliding motion with pseudopods

See multiple mucosal ulcers

Flask shaped ulcers

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11
Q

Enteric amebiasis

Nuclei in cysts and trophozoites

A

Cysts: 4

Trophozoites: 1

Also Charcot-Leyden crystals

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12
Q

E. Coli vs E. histolytica

How to tell

A

Nuclear chromatin is fine and dispersed in histolytica : sharp and central karyosome

Coarse and clumped for e. Coli: eccentric Karyosome

E: coli has 5 or more nuclei

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13
Q

Enteric amebiasis

Tx

A

Metronidazole or tinidazole

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14
Q

Balantidium coli

A

Largest intestinal protozoan

Only ciliate infxn which causes disease in the intestine of humans

In pigs

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15
Q

Cryptosporidium parvum

Transmission

A

Preweaned calves

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16
Q

If you see raspberries or mesclun lettuce

A

Pick cyclospora!!

Ingestion of sport lasted oocysts in contaminated food and water

17
Q

Cyclospora

Diagnosis and tx

A

UV fluorescence (blue or green)

Bactrim

18
Q

Microsporidia

A

Obligate intracellular parasite

19
Q

Microsporidia

Infxn by

A

Spores

20
Q

Microsporidia

Spore contains

A

Coiled polar filament, extrusion mechanism that injects spore into host cell

21
Q

Microsporidia

Sx

Diagnosis

A

Gi or keratoconjuctivitis

TEM

Tx with fumagillin or abendazole

D&T3 Exam 2 (4 decks)

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