(W2) The Clotting Cascade

Question 1

What are the Vit K dependent clotting factors?

Answer 1

IX(9), X(10), II(2), & VII(7)

Also, proteins C and S

Question 2

Heparin is a cofactor of ________ which inhibits Factors ___ activity.

Answer 2

antithrombin III,

X, IX, & II (Factors related to thrombin activity)

Question 3

What things can increase the rate of catalysis of prothrombin to thrombin?

Answer 3

Calcium, phospholipids (negative charge), cofactors