W1L3 DM

Question 1

Def

Answer 1

Group diseases char by high levels bl gluc result from defects insulin production, insulin action/ both

Question 2

Pathophysiology

Answer 2

• Insulin Deficiency
• Insulin Inefficiency(Resistance)
• Combination w dif degrees each of them

Question 3

Symptoms & signs of DM

Answer 3

• Polyuria / Nocturia
• Excessive thirst & appetite
• Weight Loss
• Lethargy
• Blurred Vision
• Skin infections
• Vaginal infections
• Tingling/numbness hands/feet
• Cuts/bruises slow heal

Question 4

Classification of Diabetes Mellitus

Answer 4

1. T1DM
2. T2DM
3. GDM
4. Others

Question 5

Type 1 diabetes

Answer 5

• Was IDDM/juvenile-onset diabetes
• Dev when body’s immune system destroys pancreatic beta cells
• > child & young adults but any age.
• 5% - 10% case

Question 6

Risk factors for type 1 diabetes

Answer 6

• Autoimmune
• Genetic
• Environmental factors

Question 7

Type 2 diabetes

Answer 7

• Was NIDDM/ adult-onset diabetes
• 90%-95% case
• Begin insulin resistance-need insulin rises- pancreas xproduce insulin

Question 8

Risk Factors for Developing Type 2 Diabetes

Answer 8

• Age>=45 years
• Fam his
• Lack exerc
• Overweight
• GDM
• low HDL/ high trigly

Question 9

Secondary DM

Answer 9

Cause

• acromegaly. -Cushing
• thyrotox. -cancer
• chro pancis

Drugs

• atyoical antipsychotic
• beta blocker. -corticosteroid
• fluoroquinolone. -thiazide

Question 10

Complications of DM

Answer 10

1. Acute (Metabolic)
   - DKA
   - Hyperosmolar non- ketomic Coma (HONK)
   - Hypoglycemia
2. Chronic (Angiopathy)
   -Microvascular disease
   (Eyes Kidneys Nerves)
   -Macrovascular disease
   (IHD, Strokes, Peripheral vas dis)