W10 Gonadal Axis in XY individuals

Question 1

Interstitial Endocrine cells

Answer 1

LH

Question 2

Sustentocytes

Answer 2

FSH

Question 3

Sperm is made in

Answer 3

Seminiferous tubules
look like spaghettis
a group is called lobule

Question 4

Most of the tube is made of sustentocytes

Answer 4

surround, support and nourish sperm development

Question 5

Interstitial endocrine cells are between tubules

Answer 5

hamin :))

Question 6

Blood-testis barrier
(tight junctions between sustntocytes)

Answer 6

toxins, immune assault, leakage of immature sperm

Question 7

Androgen binding protein

Answer 7

FSH -> sustentocyte -> synthesis of ABP -> binds testosterone -> spermatogenesis

Question 8

FSH also has negative feedback on spermatogenesis

Answer 8

Through Inhibins

Question 9

LH on interstitial endocirne cells

Answer 9

1. lets cholesterol in
2. PKA (enzyme that activates enzymes to convert cholesterol)
   Testosterones and Estrogen is made

Question 10

Estrogen in XY is needed why?

Answer 10

for bone fusion at growth age so they wont grow longer

Question 11

Negative feedbacks in XY Gonadal

Answer 11

1. T inhibits FSH and LH
2. Inhibin inhibits FSH only
   when sperm drops bellow 20 mil/mL negative feedback stops