W1 MCQs Flashcards

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1
Q

Which of the following is true when considering sperm cells, epithelial cells, fibroblasts and oocytes?

All these cells are the same size and contain the same organelles

These cells can vary in size by over 100000 x and contain the same organelles

These cells can vary in size by up to 10 x and contain the same organelles

The cells can vary in size by over 100000 x and contain different organelles to each other

These cells are the same size and contain different organelles to each other

The cells can vary in size by up to 10 x and contain different organelles to each other

A

These cells can vary in size by over 100000 x and contain the same organelles

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2
Q

The ‘central dogma’ is”:

DNA → transcription → RNA → translation → protein

DNA → translation → RNA → transcription → protein

Protein → transcription → RNA → translation → DNA

RNA → transcription → DNA → translation → protein

DNA → transcription → protein → translation→ RNA

RNA → transcription → protein → translation → DNA

RNA → translation → protein → transcription → DNA

Protein → translation → DNA → transcription → RNA

A

DNA → transcription → RNA → translation → protein

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3
Q

If a child has one grandparent on the maternal side and one grandparent on the paternal side who carries the Cystic Fibrosis gene (and the other two grandparents do not) what are the chances that the child will have Cystic Fibrosis?

100%

50%

25%

12.5%

6.25%

0%

A

6.25%

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4
Q

If red and white flowers are co-dominant, then a red x white daughter flower will be:

Red or white

Patterned containing red and white

Red

White

Pink

A

Patterned containing red and white

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5
Q

Heredity information is stored in:

DNA + RNA

RNA

DNA + protein

Protein

DNA + RNA + protein

RNA + protein

DNA

A

DNA

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6
Q

Which statement is true:
Crick and Watson….

Discovered nuclein

First used the term DNA

Identified the phosphate, sugar, base structure of DNA

Found DNA contains inherited information

Identified the bases of DNA are A, C, G, T

Solved the structure of DNA as a double helix

A

Solved the structure of DNA as a double helix

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7
Q

In DNA…

Phosphates are joined by strong covalent bonds, bases are joined by strong covalent bonds

Phosphates are joined by strong covalent bonds, bases are joined by weak hydrogen bonds

Phosphates are joined by weak hydrogen bonds, bases are joined by strong covalent bonds

Phosphates are joined by weak hydrogen bonds, bases are joined by weak hydrogen bonds

A

Phosphates are joined by strong covalent bonds, bases are joined by weak hydrogen bonds

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8
Q

Adenine shares how many bonds with thymine?

0

1

2

3

4

A

2

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9
Q

The complementary strand of 5’ TAGCGTTA 3’ is:

3’ TAACGCTA 5’

5’ TAGC 3’

5’ TAGCGTTA 3’

3’ ATCGCAAT 5’

3’ TAGCGTTA 5’

5’ ATCGCAAT 3’

A

3’ ATCGCAAT 5’

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10
Q

In the X-ray crystallography image produced by Rosalind Franklin, what is the evidence for the helix structure of DNA?

The dark smears at the top and bottom

The X pattern

The helix structure cannot be inferred from this image

The missing spots

A

The X pattern

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11
Q

How many types of bases are there in DNA?

3 or less

4

5

6 or more

A

6 or more

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12
Q

If 40% of bases in a DNA molecule are guanine, what % are adenine?

40%

30%

20%

10%

A

10%

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13
Q

Which of the following are both pyrimidines?

A and T

C and G

G and T

C and T

A and C

A and G

A

C and T

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14
Q

What is the difference between a nucleoside and a nucleotide?

Nucleotide is base + ribose; nucleoside is base + ribose + phosphate

Nucleoside is base + phosphate; nucleotide is base+ ribose + phosphate

Nucleoside is base + ribose; nucleotide is base + ribose + phosphate

Nucleoside is the side view of a nucleotide

Nucleotide is base + phosphate; nucleoside is base + ribose + phosphate

A

Nucleoside is base + ribose; nucleotide is base + ribose + phosphate

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15
Q

What are the dimensions of one full turn of DNA?

20nm wide, 34nm high

3.4 nm wide, 3.4 nm high

3.4 nm wide, 2 nm high

2nm wide, 3.4 nm high

2 nm wide, 34 nm high

2 nm wide, 2nm high

A

2nm wide, 3.4 nm high

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16
Q

Which chromosome contains the most DNA base pairs?

1

5

X

Y

They all contain the same

No one knows

A

1

17
Q

How many types of histone molecules are found in human cells?

2

3

4

5

6

A

5

18
Q

How many H1 proteins are in the nucleosome?

0

1

2

8

A

0

19
Q

When linker DNA wraps around and joins several units of core histones in a long line this is called:

A string of beads/beads on a string

A string of nucleosomes/nucleosomes on a string

A chain of nucleosomes

A chain of beads

A

A string of beads/beads on a string

20
Q

What is the name for 2 stacked nucleosomes mediated by H1?

Chromatin

Chromatosome

Chromato sandwich

Chromosome

A

Chromatosome

21
Q

Chromosomes are:

More condensed (therefore longer) during division than interphase

Less condensed (therefore shorter) during division than interphase

Always the same size in interphase or division

Less condensed (therefore longer) during division than interphase

More condensed (therefore shorter) during division than interphase

A

More condensed (therefore shorter) during division than interphase

22
Q

Chromosome territories in an interphase nucleus:

Line up in pairs in number/size order

Remain in pairs but not in number/size order

Are not necessarily in pairs but are in a defined, organised location

Are packed into the nucleus in a random, chaotic way

A

Are not necessarily in pairs but are in a defined, organised location

23
Q

Which statement is true regarding euchromatin and heterochromatin:

Euchromatin is more condensed than heterochromatin; euchromatin only contains genes involved in transcription

Euchromatin is less condensed than heterochromatin; euchromatin only contains genes involved in transcription

Euchromatin is more condensed than heterochromatin; heterochromatin only contains genes involved in transcription

Euchromatin is less condensed than heterochromatin; heterochromatin only contains genes involved in transcription

Euchromatin is less condensed than heterochromatin; euchromatin and heterochromatin both contain genes involved in transcription

A

Euchromatin is less condensed than heterochromatin; euchromatin only contains genes involved in transcription

24
Q

How many times does DNA wrap around the histone core/nucleosome?

1x

1.65x

2x

10x

16.5x

1000x

It’s not always the same

A

1.65x