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Psych 403 > W1 > Flashcards

W1 Flashcards

1
Q

what kind of decline do aging-related trajectories show?

A

modest and gradual

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2
Q

at what age does normal to gradual decline usually start at?

A

30-40

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3
Q

at what age does significant impairment levels and rapid decline to dementia start at?

A

40-50

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4
Q

AD

A

Alzheimer’s disease

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5
Q

ADRD

A

AD and Related Disorders

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6
Q

NDD

A

Neurodegenerative disease

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7
Q

NA

A

normal aging

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8
Q

MCI

A

mild cog impairment

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9
Q

BCA/BCAD

A

brain, cog, aging, dementia

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10
Q

NIH

A

US National Institutes of Health

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11
Q

CIHR

A

Canadian Institutes of Health Research

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12
Q

CCNA

A

Canadia Consortium on Neurodegeneration in Aging

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13
Q

ASC

A

Alzheimer Society of Canada

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14
Q

what are the 4 transitional “phenotypes” of BCA?

A
  • healthy/exceptional brain/cog aging
  • normal/typical brain/cog aging
  • impaired/preclinical brain/cog aging
  • diagnosed NDD and Dementia
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15
Q

how many years prior to diagnosis can NDD start?

A

5-10 yrs

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16
Q

what is the purpose of risk factors?

A

support trajectories direction

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17
Q

what is the trajectory and outcome for normal unimpaired BCA?

A
  • NA and CU
  • maintenance and typical decline
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18
Q

what is the trajectory and outcome for MCI?

A
  • at-risk state
  • potential transitional to NDD
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19
Q

what is the trajectory and outcome of NDD?

A
  • AD and Demntia
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20
Q

which group is exceptional brain grouped with?

A

normal cog aging - just diff phenotype

21
Q

what is the trajectory and outcome of exceptional brain and cog aging?

A

sustained lvls into late life

22
Q

what is the avg age of decline?

23
Q

what was the groundbreaking lecture?

A

1906
- Dr. Alois Alzheimer identified “unusual disease of cerebral cortex”
-> identified in 55 yr old woman who died

24
Q

what did Dr. Alz discover in the tissue?

A

many globs of sticky proteins in spaces b/w neurons and tangled bundle of fibrils within neurons
- beta-amyloid plaques
- neurofibrillary tangles

25
Q

what was the hallmark of AD?

A

plaques and tangles

26
Q

who was Frau August D?

A

51 yr old lady with serious memory problems, sus behavior (thought ppl were conspiring against her), language problems

27
Q

what was the trajectory for Frau Auguste D?

A

rapid degeneration of all symptoms
spreading decline across other domains
bedridden

28
Q

ich habe mich verloren

A

i have lost myself
- identity and memory

29
Q

what did Frau’s autopsy show?

A

AD observed - dramatic shrinkage in cerebral cortex
- abnormal deposits in and around cells
- fatty deposits in small blood cells

30
Q

risk factor

A

increases risk of disease/condition

31
Q

protection factor

A

decreases risk of disease/condition

32
Q

incidence

A

number/rate of disease in time frame

33
Q

prevalence

A

total number of cases at specified time
- larger than incidence

34
Q

what was Dr.Goldman’s rationale?

A

dementia is the greatest health challenge of Canada’s aging. we don’t know the scale of the challenge and the impact on Canadians

35
Q

how many Canadians have dementia?

36
Q

what are the 5 main goals of the Landmark study?

A
  • clarify the path forward: update public knowledge and how we expect numbers to change over next 30 yrs
  • improve knowledge: break down complexity and highlight key areas of risk reduction
  • advocate: many ppl support ppl w dementia and provide formal and informal care
  • create action: inspire many type of ppl including gov’t to support and work towards programs and policies to promote better brain health
  • push for change: need for action -> funding, changes, reduce stigma and stereotypes and implement solutions
37
Q

how many ppl each day in 2022 were diagnosed with dementia?

38
Q

how many hours per week does someone spend taking take of a person with dementia?

A

26 hours a week

39
Q

what are the key gaps needed to be addressed?

A
  • incomplete understanding of risk and protective factors
  • home care and long-term care sys -> under strain and facing crises, need a remodel of care sys
  • the challenges associated with providing care (financial, burnout, depression, isolation)
40
Q

how many cases between 2020-2049?

41
Q

what is the major risk factor for dementia?

42
Q

who is more likely to get dementia?

43
Q

what 4 provinces have the highest number of cases?

A

ontario
quebec
bc
ab
-> fastest growing provinces

44
Q

t or f: the project prevalence and incidence for AB citizens is consistent

45
Q

what is Alz Association motto?

A

our vision is a world without Alz disease

46
Q

what is the 6th leading cause of death?

47
Q

how much could ADRD cost by 2050?

A

1.1 trillion

48
Q

how many Americans will have AD by 2050?

49
Q

what did Dr.Khachaturian do?

A

discovered a crucial historical link in emergence of AD public awareness, scientific research and intervention efforts

Psych 403 (10 decks)

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