Extra from W6

Question 1

what are the 3 themes for the CCNA?

Answer 1

prevention
treatment and secondary prevention
quality of life

Question 2

what is the purpose of the knowledge translation and exchange?

Answer 2

to explain what is being done in everday words

Question 3

what is the basic foundation of CCNA research?

Answer 3

neuroimaging- national standardized MRI dementia protocol

Question 4

what is the canadian version of FINGER?

Answer 4

CAN-THUMBS UP: prevention study for persons at risk of dementia

Question 5

what is used as a general data collection?

Answer 5

LORIS

Question 6

what are the 2 spectra of ADRD?

Answer 6

AD (SCI, MCI, AD) and LBD (PD, PD-MCI, PDD, LBD)

Question 7

what is the goal of T9 biomarker and RA research?

Answer 7

characterize and discriminate phenotype heterogeneity
- detect early markers
- differentiate clinical groups with biomarkers and RF
- monitor and predict clinical progression

contribute to identifying secondary phenotypes (detected) - trajectories toward and away from AD

contribute to biomarkers for prevention trials
- synergic, can thumbs up
emphasis on precision, generalizability and representation

focus on modern approaches and new technologies

Question 8

what are the seven dimensions of biomarker and risk factors that influence NDD?

Answer 8

intensity
evidence
complexity - multiple dimensions
interactive
general/precision
dynamic
risk/protection

Question 9

who was the lead for women, sex, gender and dementia?

Answer 9

Dr gillian einstein

Question 10

what was the goal of Einstein?

Answer 10

work with CCNA to ensure sex and gender research questions will be studied across spectrum in human and animal

Question 11

why is it important to learn about sex and gender differences?

Answer 11

the interaction is critical for developing interventions for both prevention and treatment of ND

Question 12

what is the role of CCNA in WSGD?

Answer 12

monitor sex and gender
-> support and encourage all researchers to consider sex and gender differences in aging, cognition, dementia, dementia care and caregiving (review manuscripts)
- highlight and advocate

Question 13

what are the emerging notes about WSGD?

Answer 13

• globally mixed results about W>M
• rf vary in 4 ways:
  same frequency, diff effect (APOE4 and 2)
  same effect, diff freq (ed, smoking, exercise)
  both diff freq and effect (head trauma)
  restricted to W or M (oophorectomy, prostate cancer)
• menopause (early is a rf)
  -> ovary removed before 40 have greater risk for AD
  40-45 = slightly greater risk bc of estrogen

Question 14

what is the ICHP?

Answer 14

indigenous cognitive health program

Question 15

what is the purpose of ICHP?

Answer 15

building capacity to support respectful and safe dementia research partnerships
-> culturally safe

Question 16

what is the culturally-safe cognitive assessment tool?

Answer 16

CICA
- canadian indigenous cognitive assessment

Question 17

what is the comprehensive suite of online learning resources?

Answer 17

pathway to culturally safe indigenous health research practices

Question 18

who talked about ICH?

Answer 18

dr jennifer walker

Question 19

what are the main goals of ICH within CCNA?

Answer 19

• support healthy, respectful, dementia research partnerships b/w communities and researchers
• provide foundational knowledge on developing relationships and engaging with Indigenous communities and health organizations
• offer resources and opportunities to learn about culturally safe approaches
• explore data sovereignty principles

Question 20

what is key to indigenous research?

Answer 20

ethics
- prevents deciding to do research without communication and careful consideration of safe and respectful practices

Question 21

what are the 4 steps in CCNA ICH program?

Answer 21

1. establish foundational knowledge on impacts of colonization on Indigenous health
2. enhance knowledge on Indigenous health research
3. learn about FN, M, Inuit Data Sovereignty Principles in research
4. complete training on conducting ethical research with Indigenous peoples

Question 22

what are some ways to prevent D by aging well?

Answer 22

• healthy body - healthy mind
• stay connected (social and physical engagement)
• take time to heal
• learn to age well across life course: elders and youth connect by teaching words from language

Question 23

what is CCNA?

Answer 23

continuing large-scale national initiative to address issues regarding aging, NDD and D

Question 24

what is the current phase of CCNA?

Answer 24

new data collection with selected cohorts (current phase)
- focus on balancing sex/gender and education/SES differences

Question 25

what has the CCNA been a catalyst for?

Answer 25

hub for Canadian dementia research, practice, translation, and representation
- pivotal player in international efforts to address global rising tide of dementia

Question 26

what is the goal of the NDS?

Answer 26

aspiration
- annual investment in dementia research in Canada exceeds one percent of dementia care costs

Question 27

what is the annual cost of dementia care in canada?

Answer 27

10-12 billion

Question 28

how much does federal cost estimate to?

Answer 28

0.4% of annual costs to Canada’s economy

Question 29

what does decreasing AD prevalence by 50% require?

Answer 29

decrease AD costs by 50%

Question 30

how much money does federal need for research to reach the 1% goal

Answer 30

100M/yr