Vulval/vaginal lump Flashcards

1
Q

What are the causes of a vulval/vaginal lump

A

Bartholin’s gland cyst or abascess
Vaginal cyst
vulval cancer
Infection: herpes simplex, syphilis, HPV, molluscum
Labial abscess
Sebaceous/epidermoid cyst
Skin tag

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2
Q

What is a Bartholin cyst

A

Common, benign lesion of the vulva, representing a dilatation of the duct of Bartholin’s glands

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3
Q

What is the difference between a cyst and abscess

A

Cyst = collection of fluid within a sac
Abscess = collection of pus resulting from infection

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4
Q

What is the cause of Bartholin Cyst/abscess

A

If the Bartholin’s duct is obstructed, a cyst forms which contains sterile muscus
Mucus becomes colonised and therefore infected, an abscess will form.
The most common causative organisms are staphylococcus, streptococcus and E. Coli. Gonococci can also rarely cause an abscess.

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5
Q

What is the epidemiology of Bartholin cyst

A

Affects 1 in 50 women
Higher risk in sexually active women aged 20-30
STIs are a risk factor
Uncommon in children/after menopause

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6
Q

What are the signs and symptoms of Bartholin cysts

A

Tender unilateral swelling, unable to sit or walk
- lower part of the vestibule
Dyspareunia and vague pelvic pain
Surrounding labial oedema, palpable lymph nodes
Systemically unwell e.g. fever
Urinary irritation

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7
Q

What is the management for Bartholin cyst

A

Conservative: analgesia, warm soak/compress
Medical: swab for MC&S and Abx
Surgical:
- Incision and drainage under LA or GA
- Balloon (Word) catheter insertion: LA, left to drain for 2 weeks with Abx
- Marsupialisation
- Bartholin’s gland removal

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8
Q

Describe marsupialisation

A

Minor surgical procedure used to treat Bartholin cysts, where the cyst is cut and drained. The edge of the cyst are sutured to the surrounding tissue, forming a small pouch, which allows fluid to drain freely

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9
Q

Describe vaginal cysts

A

Congenital cysts
Smooth white appearance, may be as large as a golf ball
When in the vagina it is often mistaken as a prolapse

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10
Q

Describe vaginal adenosis

A

Columnar epithelium found in the squamous epithelium of the vagina
Commonly occurs in women whose mothers receive diethylstilboestrol (DES) in pregnancy
- Women with DES exposure in utero are screened annually by colposcopy
Usually resolves spontaneously but has a small risk of turning malignant - clear cell carcinoma of the vagina

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11
Q

Define VIN

A

Vulvar intraepithelial neoplasia (VIN) = presence of atypical cells in the vulval epithelium

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12
Q

What are the types of VIN

A

Usual type
- Warty, basaloid, mixed
- Common in women aged 35-55
- RF: HPV (esp. HPV-16) | cervical intraepithelial neoplasia CIN | smoking | chronic immunosuppression
- Multifocal: Appearance varies widely: red, white, pigmented, plaques, papules, patches, erosions, nodules, warty, hyperkeratosis

Differentiated type
- Associated with lichen sclerosis
- Seen in older women
- Unifocal: ulcer or plaque
- Associated with keratinising squamous cell carcinomas of the vulva
- Risk of progression to cancer is higher than usual type VIN

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13
Q

What is the management for VIN

A

Local surgical excision to relieve symptoms
Supportive: emollients, mild topical steroid

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14
Q

What are the most common carcinomas of the vulva and what are the risk factors

A

95% of vulval malignancies are squamous cell carcinomas, the rest are melanomas, basal cells carcinomas, adenocarcinomas, and a variety of others

RF: lichen sclerosis | immunosuppression | smoking | Paget’s disease of the vulva

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15
Q

What are the signs and symptoms of vulval carcinoma

A

Presentation: pruritus, bleeding, discharge, mass found
Examination: ulcer or mass (most commonly labia majora, clitoris) | tender and/or hard inguinal lymphadenopathy

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16
Q

What investigations should be done for vulval carcinoma

A

2ww referral
Biopsy of lesion
Fitness for surgery: CXR, ECG, FBC, U&Es, cross match

17
Q

What is the staging for vulval carcinoma

A

1a: confined to vulva/perineum <2cm, stromal invasion <1mm
1b: confined to vulva/perineum >2cm, stromal invasion >1mm
2: adjacent spread (urethra, vagina, anus)
3. Positive inguinofemoral nodes
4: invades upper urethra/vagina, rectum, mets

18
Q

What is the management for vulval carcinoma

A

1a: local excision ± plastic surgeon
1b/2/3/4:
- sentinel lymph node biopsy
- Wide local excision and groin lymphadenectomy (triple incision radical vulvectomy)
± Plastic surgeon input

19
Q

What is the management for:
- Vaginal mass (unexplained and palpable) in or at the entrance to the vagina
- Vulval bleeding (unexplained) in women
- Vulval lump or ulceration (unexplained)

A

All: consider 2 week wait pathway referral