VTE

Question 1

Standard dose of LDUH

for VTE PPX

Answer 1

5000 units SC BID

5000 units SC q8hr

Question 2

Standard Dose of LMWH (Lovenox)

for VTE PPX

Answer 2

40 mg SC QDay
or
30 mg SC BID

Obesity: 0.5 mg/kg SC
Renal Failure: 30 mg QDay

Question 3

Thromboprophylaxis in major abdominal surgery patients

Answer 3

Low-dose unfractionated heparin
or
LMWH + SCDs

Question 4

Work-up for PE

Answer 4

1. Proximal leg venous compressive & doppler US
2. CT angio
3. Radionuclide lung scan

Question 5

Treatment of non life-threatening VTE

Answer 5

Initial bolus of 80 IU/kg

Continuos infusion of 18 IU/kg/hr

Question 6

Reversal of heparin

Answer 6

Protamine sulfate (1mg/100 units heparin)

protein from fish sperm

Question 7

Thrombolytic therapy in acute PE

Answer 7

Alteplase (100mg infused over 2hr)

Embolectomy

Vena cava filter

Question 8

Indications for vena cava filter

Answer 8

DVT + absolute contraindication to anticoag

PE while on full anticoagulation

Large free-floating thrombus

Low cardiopulmonary reserve/pulmonary HTN

Spinal cord injury