Vomiting and malabsorption 1 (PS & GOR) Flashcards

1
Q

What are the physiological phases of vomiting?

What symptoms/signs define each stage

A

Pre-ejection phase:

  • Pallor
  • Nausea
  • Tachycardia

Ejection phase:

  • Retch
  • Vomit

Post-ejection phase:

  • may feel better
  • Shivering
  • Lethargy
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2
Q

What are the potential triggers of vomiting?

A

GI triggers - enteric pathogens, allergies, obstructions

Infections

Head injuries / raised ICP

Inner ear stimuli (motion sickness, vertigo etc)

Visual / olfactory stimuli or fear

Metabolic derangements, chemotherapy

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3
Q

What are the different types of vomiting?

A

Vomiting with retching

Projectile vomiting

Bilious vomiting

Effortless vomiting (regurgitation)

Haemetemesis

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4
Q

How does retching work?

A

Deep inspiration against closed glottis

Abdominal contraction

Together^ pressure difference displaces gastric contents up

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5
Q

What are the main causes of vomiting in infants?

A

GOR

cows milk allergies

infection

intestinal obstruction

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6
Q

What are the main causes of vomiting in children?

A

gastroenteritis

appendicitis

infection

intestinal obstruction

raised ICP

coeliac disease

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7
Q

What are causes of vomitng in young adults?

A

Gastroenteritis

Infection

H.Pylori infection

Appendicitis

Raised ICP

DKA

Cyclical vomiting syndrome

Bulimia

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8
Q

What is pyloric stenosis?

When does it tend to present in a baby’s life?

What sex is more likely to get it?

A

Thickened narrowing of the pyloric sphincter

Babies 4-12 weeks

Boys > girls

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9
Q

Give the typical presentation for pyloric stenosis

A

Baby boy, 4-12 weeks old

Projectile, non-billious vomiting - after every feed

Weight loss

Dehydration +/- shock

Electrolyte disturbance

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10
Q

What is the characteristic electrolyte disturbance seen in pyloric stenosis?

A

Hypokalaemic, hypocholeremic metabolic alkalosis

Decreased potassium

Decreased chloride

Increased pH

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11
Q

What feature on examination of a beby is characteristic of pyloric stenosis

A

Olive mass - on palpation of epigastrum

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12
Q

Describe the clinical significance of effortless vomiting

What usually causes it?

What are the rarer causes?

A

Happens to near enough all babies - most commonly caused by GOR

Usually self limiting and will resolve - with the exception of:

Cerebral palsy

Progessive neurological problems

Oesophageal atresia +/- Tracheosophageal fistula operation

Generalised GI motility problem

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13
Q

Why does GOR happen in babies?

A

Relaxed LOS

Babies are supine a lot

Liquid feed

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14
Q

How might neonatal GORD present?

A

Vomiting - rarely haemetemesis

Feeding problems & failure to thrive

Respiratory symptoms - apnoea, cough, wheeze, chest infections

Sandifer’s syndrome - spastic torticollis (neck bending) and dystonic body movements

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15
Q

What age range is GOR expected in infants?

From what age would investigation be needed?

Why might investigation be warrented earlier?

A

Starts at 2 weeks

Worst 4-6 months

Stops after a year

If it does not improve after a year of age then investigation is indicated

Can be indicated <1 year if growth faltering

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16
Q

How is reflux diagnosed in yungers?

A

History & examination - often sufficient

Oesophageal pH & impedance monitoring

Radiological investigations - video fluroscopy, barium swallow

UGIE

17
Q

What problems can a Barium swallow indicate?

A

Hiatus hernia

Oesophageal dysmotility

Reflux

Gastric emptying

Strictures

18
Q

How is infant GORD treated?

A

Usually - feeding advice & nutritional support

Rarely - medical management

V rarely - Surgery

19
Q

One of the aspects of feeding advice for GOR involves ensuring the feeding volumes for the child are correct

What are the correct feeding volumes for:

a) Neonates
b) Infants

A

a) Neonates

150 mls/kg/day

b) Infants

100 mls/kg/day

20
Q

Describe the nutrional support offered to patients with persistent GOR

How about in patients with persistent GOR due to cerebral palsy ?

A

1) Calorie supplements

if not working…

2) Exclusion diet trial (cows milk protein free diet) - for 4 weeks and review

For kids with CP - Nasogastric tube

Gastrostomy

21
Q

What medical treatments may be offered to infants with persistent GOR?

A

H2 receptor antagonists - Ranitidine etc

PPI - Omeprazole

22
Q

What are the indications for surgical treatment of GOR?

A

If persistent - despite feeding advice, nutritional support and medical treatment

and

If presence of:

  • failure to thrive
  • persistent aspiration
  • oesophagitis
23
Q

What surgical procedure is done for GOR in kids?

A

Nissen fundoplication (same as for hiatus hernia in adults)